ID A0A196R018_9RHOB Unreviewed; 740 AA.
AC A0A196R018;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=A8B74_00315 {ECO:0000313|EMBL:OAN98132.1};
OS Sulfitobacter geojensis.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Roseobacteraceae; Sulfitobacter.
OX NCBI_TaxID=1342299 {ECO:0000313|EMBL:OAN98132.1, ECO:0000313|Proteomes:UP000078317};
RN [1] {ECO:0000313|Proteomes:UP000078317}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=EhN01 {ECO:0000313|Proteomes:UP000078317};
RA Rosana A., Orata F., Boucher Y., Case R.;
RL Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OAN98132.1}.
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DR EMBL; LXYM01000001; OAN98132.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A196R018; -.
DR STRING; 1342299.Z947_2588; -.
DR eggNOG; COG5000; Bacteria.
DR Proteomes; UP000078317; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd06225; HAMP; 1.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd00130; PAS; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 6.10.340.10; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR017232; NtrY.
DR InterPro; IPR045671; NtrY-like_N.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013767; PAS_fold.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR PANTHER; PTHR43065:SF10; PEROXIDE STRESS-ACTIVATED HISTIDINE KINASE MAK3; 1.
DR PANTHER; PTHR43065; SENSOR HISTIDINE KINASE; 1.
DR Pfam; PF00672; HAMP; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF19312; NtrY_N; 1.
DR Pfam; PF00989; PAS; 1.
DR PIRSF; PIRSF037532; STHK_NtrY; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00304; HAMP; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF158472; HAMP domain-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50885; HAMP; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50112; PAS; 1.
PE 4: Predicted;
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:OAN98132.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000078317};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 16..36
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 56..75
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 87..111
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 290..311
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 312..365
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 377..418
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 502..727
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 740 AA; 81358 MW; 8D86F104F951E3CE CRC64;
MERLGRLRRL KRVRNLSTLG LVVLGPVLAM ATYLALGPLG QGANTLSLRL VLLTDLVYVL
LVAALVLSQV ARLIAARRAK SAGSRLHLRL TGVFALMALI PTVTVAVFAG LTVNVGLEGW
FSDRVRGVVG SSLAAAQAYE AEQRQDLIED ARALARNIDN ARNQGINLSD SQLLGEGQRQ
IQRGLREAYL IDSTAEIRAR GDRSYLFDYE KPTGAQLTAA ADQGLLVIED WPNNEFRALV
PMQSFLDRYL YVSRDVDGKI LSLLDETTET VRLYQQLESD RGRLLFEFGL LYLGFAVILI
LAAVWLGLWF AERLSGPVGR LTGAAQQVGA GNLNVQVREE DGDDEIAMLG RYFNQMTKQL
QGQRETLLDN TRQIERRRRL FDSVLSSVTS GVVGLDPEGR VTFVNRSAMR LLDWSEEQQS
VSLSVAVPEF GPLFETISAK QGDTAQEEIK VSRQGAMENL LVRMATRRTG DGRLEGYVVA
FDDVTDLVSA QRMAAWGDVA QRIAHEIKNP LTPIQLSAER IRRKFAPKLG DDSDSLEQMT
GVIIRQTGDL RRIVDEFSKF ARMPEPETSE HNLTQLVKDA VFLQQSGQPE VKILSDLGEG
VVMADIDATM ISQALNNLIK NAGEAIESLQ KSDAPENLKP QIRVTLQHSD ASATLTIADN
GIGLPEDRAR LFEPYVTTRS EGTGLGLPIV KKIIEEHGGT LTLDNAPVFE GQDHFGAMAV
ISLPLVPSPQ PAKRVETADE
//
