ID   A0A196S406_BLAHN        Unreviewed;       937 AA.
AC   A0A196S406;
DT   05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2016, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   SubName: Full=Vam6/Vps39-like protein {ECO:0000313|EMBL:OAO11885.1};
GN   ORFNames=AV274_6435 {ECO:0000313|EMBL:OAO11885.1};
OS   Blastocystis sp. subtype 1 (strain ATCC 50177 / NandII).
OC   Eukaryota; Sar; Stramenopiles; Bigyra; Opalozoa; Opalinata; Blastocystidae;
OC   Blastocystis.
OX   NCBI_TaxID=478820 {ECO:0000313|EMBL:OAO11885.1, ECO:0000313|Proteomes:UP000078348};
RN   [1] {ECO:0000313|EMBL:OAO11885.1, ECO:0000313|Proteomes:UP000078348}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 50177 / NandII {ECO:0000313|Proteomes:UP000078348};
RA   Gentekaki E., Curtis B., Stairs C., Eme L., Herman E., Klimes V.,
RA   Arias M.C., Elias M., Hilliou F., Klute M., Malik S.-B., Pightling A.,
RA   Rachubinski R., Salas D., Schlacht A., Suga H., Archibald J., Ball S.G.,
RA   Clark G., Dacks J., Van Der Giezen M., Tsaousis A., Roger A.;
RT   "Nuclear genome of Blastocystis sp. subtype 1 NandII.";
RL   Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OAO11885.1}.
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DR   EMBL; LXWW01000576; OAO11885.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A196S406; -.
DR   STRING; 478820.A0A196S406; -.
DR   OrthoDB; 38195at2759; -.
DR   Proteomes; UP000078348; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR   GO; GO:0043231; C:intracellular membrane-bounded organelle; IEA:UniProt.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:UniProtKB-UniRule.
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
DR   Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR   InterPro; IPR000547; Clathrin_H-chain/VPS_repeat.
DR   InterPro; IPR001180; CNH_dom.
DR   InterPro; IPR032914; Vam6/VPS39/TRAP1.
DR   InterPro; IPR019452; VPS39/TGF_beta_rcpt-assoc_1.
DR   InterPro; IPR019453; VPS39/TGF_beta_rcpt-assoc_2.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   PANTHER; PTHR12894; CNH DOMAIN CONTAINING; 1.
DR   PANTHER; PTHR12894:SF27; TRANSFORMING GROWTH FACTOR-BETA RECEPTOR-ASSOCIATED PROTEIN 1; 1.
DR   Pfam; PF00780; CNH; 1.
DR   Pfam; PF10366; Vps39_1; 1.
DR   Pfam; PF10367; Vps39_2; 1.
DR   SUPFAM; SSF50978; WD40 repeat-like; 1.
DR   PROSITE; PS50236; CHCR; 1.
DR   PROSITE; PS50219; CNH; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Reference proteome {ECO:0000313|Proteomes:UP000078348}.
FT   DOMAIN          16..299
FT                   /note="CNH"
FT                   /evidence="ECO:0000259|PROSITE:PS50219"
FT   COILED          677..704
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   937 AA;  106763 MW;  9ADBE9B237B4A0D9 CRC64;
     MSIQVFNESK VVTSGRNKIT SVTSDTTHIY VSLKDGKLFV YERIDGPGLQ FRESGEIPNF
     SGCKKGAIMM HCVEKWNLLF ALNDKGIAIH ELNNLQNGSY LPNTSGCSLM AFDENRHVVV
     ASWKRKIYVF QLRDQVPLNK CFVKEIILPD TVLCMEFLNS LLFVGYKREY CLVDINQGRS
     CKDICEISKS TSKPFCVRIQ QGEGICNGNG DENDTKEQGE MLLANDRKGL FYDFVGSPAR
     GKGQHLEWQT DAIGGAYLCP YFLALTTNGV EVFNSWRYQP IQTIPMSSPK YIEEAHFLSN
     GQSVDGCLVC TQQVVYVLQM LSLPQQITTL ISDQYKCFDD ALTLCSLFPR GKEQLRDQFK
     TQISRLKGLY LFSEGKYDSA ISFLQRGMVP TQQVLSLYPS IIPDSLPTNI SPYPQRVFQS
     RYEENQAIEA LLPLLNTRRQ QLLMKLSQLK SLQDKDNTDP DASGLGYSSV IHLSVAEEDT
     TQIWQDLTLI DTVLLRAYVR TNRPAIIPFL RHENFVPFDD AQQLLAGAGM EPELIALYST
     HHKHDLAIAQ ILQPLRDTTL SPTERQQRLM DLVHYLQQLG SDYQELIFDC SRMFYKESRQ
     LVLELFVNYH PVDGGQPIDC ETIRQHLHDL SEGDEQLKND WEKNALEITY LRHCIGDKNE
     GSPNFHTRLV LLYAQSISSL SASIQTLKKK CEEVETKEED KEADYSSMLN GMSLMITQRE
     ELLLRSKKEL LEFLELSDQY DITLILEKLS GNEFLEEQAI ILSKSGEYLN ALSIIAHRLG
     NINMADAYCT KIFNSGKNPD IFLHLIKTYL YPPKDSTLSK EDSIHLALRV FSSHFDKVDP
     IVVFNLLPDS LPLEEVMECI EVNLTKLDEK RRNMLMLRQL AEVRRLAVSE EYMNMRNSSF
     ENTSTTICPV CKRVIGDSVF TWNPNGVIMH TACAIPK
//