ID A0A196SAM3_BLAHN Unreviewed; 306 AA.
AC A0A196SAM3;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=Lupus La protein {ECO:0000313|EMBL:OAO13152.1};
GN ORFNames=AV274_5156 {ECO:0000313|EMBL:OAO13152.1};
OS Blastocystis sp. subtype 1 (strain ATCC 50177 / NandII).
OC Eukaryota; Sar; Stramenopiles; Bigyra; Opalozoa; Opalinata; Blastocystidae;
OC Blastocystis.
OX NCBI_TaxID=478820 {ECO:0000313|EMBL:OAO13152.1, ECO:0000313|Proteomes:UP000078348};
RN [1] {ECO:0000313|EMBL:OAO13152.1, ECO:0000313|Proteomes:UP000078348}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 50177 / NandII {ECO:0000313|Proteomes:UP000078348};
RA Gentekaki E., Curtis B., Stairs C., Eme L., Herman E., Klimes V.,
RA Arias M.C., Elias M., Hilliou F., Klute M., Malik S.-B., Pightling A.,
RA Rachubinski R., Salas D., Schlacht A., Suga H., Archibald J., Ball S.G.,
RA Clark G., Dacks J., Van Der Giezen M., Tsaousis A., Roger A.;
RT "Nuclear genome of Blastocystis sp. subtype 1 NandII.";
RL Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OAO13152.1}.
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DR EMBL; LXWW01000454; OAO13152.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A196SAM3; -.
DR STRING; 478820.A0A196SAM3; -.
DR OrthoDB; 5477115at2759; -.
DR Proteomes; UP000078348; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:InterPro.
DR GO; GO:1990904; C:ribonucleoprotein complex; IEA:UniProtKB-UniRule.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006396; P:RNA processing; IEA:InterPro.
DR CDD; cd07323; LAM; 1.
DR CDD; cd12291; RRM1_La; 1.
DR CDD; cd00590; RRM_SF; 1.
DR Gene3D; 3.30.70.330; -; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR045180; La_dom_prot.
DR InterPro; IPR006630; La_HTH.
DR InterPro; IPR014886; La_xRRM.
DR InterPro; IPR002344; Lupus_La.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR22792:SF172; LUPUS LA PROTEIN HOMOLOG; 1.
DR PANTHER; PTHR22792; LUPUS LA PROTEIN-RELATED; 1.
DR Pfam; PF05383; La; 1.
DR Pfam; PF00076; RRM_1; 1.
DR Pfam; PF08777; RRM_3; 1.
DR PRINTS; PR00302; LUPUSLA.
DR SMART; SM00715; LA; 1.
DR SMART; SM00360; RRM; 2.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50961; HTH_LA; 1.
DR PROSITE; PS50102; RRM; 2.
DR PROSITE; PS51939; XRRM; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000078348};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW ProRule:PRU00332}.
FT DOMAIN 1..90
FT /note="HTH La-type RNA-binding"
FT /evidence="ECO:0000259|PROSITE:PS50961"
FT DOMAIN 96..177
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 186..306
FT /note="XRRM"
FT /evidence="ECO:0000259|PROSITE:PS51939"
FT DOMAIN 191..264
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT REGION 282..306
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 284..306
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 306 AA; 35465 MW; 79FB7565580E6864 CRC64;
MSEDLATKIR RQVEFYFSGL NLNRDKFMRE KMSADPDGFM PIETLLTFNR LKQLTTDMKV
VVDAIKKSDK LAFNDDFTKV KSNIDFRKPE NNVALRTVHM RGFPTSATLD DLLEGLKPYG
NIRFIEMRRF ISNKEFKGSV NVEFNTKEEA EEFMKKKIMF AGVEIMEKEL LADREKSFDE
KNKRYKYTPD SLLQIRNIGK DTTAEALQEF LKPYMDQYSY IFRTEGDNQA VVRFATSQEA
AKALNELKDK TLSDKPLKLM ILRGKKANGM WTKIKSLMLS EEAAKKTSQK RENEAEEGGE
KKAKTD
//
