ID A0A196SF70_BLAHN Unreviewed; 244 AA.
AC A0A196SF70;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=DNA repair endonuclease ERCC1 {ECO:0000313|EMBL:OAO14792.1};
GN ORFNames=AV274_3496 {ECO:0000313|EMBL:OAO14792.1};
OS Blastocystis sp. subtype 1 (strain ATCC 50177 / NandII).
OC Eukaryota; Sar; Stramenopiles; Bigyra; Opalozoa; Opalinata; Blastocystidae;
OC Blastocystis.
OX NCBI_TaxID=478820 {ECO:0000313|EMBL:OAO14792.1, ECO:0000313|Proteomes:UP000078348};
RN [1] {ECO:0000313|EMBL:OAO14792.1, ECO:0000313|Proteomes:UP000078348}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 50177 / NandII {ECO:0000313|Proteomes:UP000078348};
RA Gentekaki E., Curtis B., Stairs C., Eme L., Herman E., Klimes V.,
RA Arias M.C., Elias M., Hilliou F., Klute M., Malik S.-B., Pightling A.,
RA Rachubinski R., Salas D., Schlacht A., Suga H., Archibald J., Ball S.G.,
RA Clark G., Dacks J., Van Der Giezen M., Tsaousis A., Roger A.;
RT "Nuclear genome of Blastocystis sp. subtype 1 NandII.";
RL Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the ERCC1/RAD10/SWI10 family.
CC {ECO:0000256|ARBA:ARBA00008283}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OAO14792.1}.
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DR EMBL; LXWW01000210; OAO14792.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A196SF70; -.
DR STRING; 478820.A0A196SF70; -.
DR OrthoDB; 103226at2759; -.
DR Proteomes; UP000078348; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003684; F:damaged DNA binding; IEA:InterPro.
DR GO; GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0006310; P:DNA recombination; IEA:UniProt.
DR GO; GO:0006302; P:double-strand break repair; IEA:UniProt.
DR Gene3D; 3.40.50.10130; -; 1.
DR Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR InterPro; IPR047260; ERCC1-like_central_dom.
DR InterPro; IPR004579; ERCC1/RAD10/SWI10.
DR InterPro; IPR011335; Restrct_endonuc-II-like.
DR InterPro; IPR010994; RuvA_2-like.
DR PANTHER; PTHR12749:SF0; DNA EXCISION REPAIR PROTEIN ERCC-1; 1.
DR PANTHER; PTHR12749; EXCISION REPAIR CROSS-COMPLEMENTING 1 ERCC1; 1.
DR Pfam; PF14520; HHH_5; 1.
DR Pfam; PF03834; Rad10; 1.
DR SUPFAM; SSF52980; Restriction endonuclease-like; 1.
DR SUPFAM; SSF47781; RuvA domain 2-like; 1.
PE 3: Inferred from homology;
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Endonuclease {ECO:0000313|EMBL:OAO14792.1};
KW Hydrolase {ECO:0000313|EMBL:OAO14792.1};
KW Nuclease {ECO:0000313|EMBL:OAO14792.1};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000078348}.
FT DOMAIN 63..161
FT /note="ERCC1-like central"
FT /evidence="ECO:0000259|Pfam:PF03834"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..19
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 244 AA; 27774 MW; A94674D1F25CDA37 CRC64;
MKRSAPEGTP SSGSLSDKRN AGVTFYMEEE KEYTVNERMV YYKPNPLNNR IVSNSPSLKM
IKKFGMLPDF EINDDICVFV RDISDYTKRP EEVFSMHRKL SAPNQPTSHS YVLSVFLLIL
GRDAMNTIAV EEVSAKCVFE GLSFLICWSV EEAASYLNTI KAYETRGSDI IQKHTHKDLE
SQAVRVLTNI NGVNVNNATD LMKKYRTMSD IMTASLDDLS ELPGMGDKRV LNVYRAFQQQ
KREE
//
