ID A0A197JQ77_9FUNG Unreviewed; 1031 AA.
AC A0A197JQ77;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 22-FEB-2023, entry version 23.
DE RecName: Full=ER membrane protein complex subunit 1 {ECO:0000256|ARBA:ARBA00020824};
GN ORFNames=K457DRAFT_157460 {ECO:0000313|EMBL:OAQ26616.1};
OS Linnemannia elongata AG-77.
OC Eukaryota; Fungi; Fungi incertae sedis; Mucoromycota; Mortierellomycotina;
OC Mortierellomycetes; Mortierellales; Mortierellaceae; Linnemannia.
OX NCBI_TaxID=1314771 {ECO:0000313|EMBL:OAQ26616.1, ECO:0000313|Proteomes:UP000078512};
RN [1] {ECO:0000313|EMBL:OAQ26616.1, ECO:0000313|Proteomes:UP000078512}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AG-77 {ECO:0000313|EMBL:OAQ26616.1,
RC ECO:0000313|Proteomes:UP000078512};
RG DOE Joint Genome Institute;
RA Uehling J., Gryganskyi A., Hameed K., Tschaplinski T., Misztal P., Wu S.,
RA Desiro A., Vande Pol N., Du Z.-Y., Zienkiewicz A., Zienkiewicz K.,
RA Morin E., Tisserant E., Splivallo R., Hainaut M., Henrissat B., Ohm R.,
RA Kuo A., Yan J., Lipzen A., Nolan M., Labutti K., Barry K., Goldstein A.,
RA Labbe J., Schadt C., Tuskan G., Grigoriev I., Martin F., Vilgalys R.,
RA Bonito G.;
RT "Genome sequencing reveals origins of a unique bacterial endosymbiosis in
RT the earliest lineages of terrestrial Fungi.";
RL Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBUNIT: Component of the ER membrane protein complex (EMC).
CC {ECO:0000256|ARBA:ARBA00011276}.
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000256|ARBA:ARBA00004115}; Single-pass type I membrane protein
CC {ECO:0000256|ARBA:ARBA00004115}. Membrane
CC {ECO:0000256|ARBA:ARBA00004479}; Single-pass type I membrane protein
CC {ECO:0000256|ARBA:ARBA00004479}.
CC -!- SIMILARITY: Belongs to the EMC1 family.
CC {ECO:0000256|ARBA:ARBA00007904}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KV442065; OAQ26616.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A197JQ77; -.
DR STRING; 1314771.A0A197JQ77; -.
DR OrthoDB; 37872at2759; -.
DR Proteomes; UP000078512; Unassembled WGS sequence.
DR GO; GO:0072546; C:EMC complex; IEA:InterPro.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR026895; EMC1.
DR InterPro; IPR011678; EMC1_C.
DR InterPro; IPR018391; PQQ_beta_propeller_repeat.
DR InterPro; IPR002372; PQQ_repeat.
DR InterPro; IPR011047; Quinoprotein_ADH-like_supfam.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR PANTHER; PTHR21573:SF0; ER MEMBRANE PROTEIN COMPLEX SUBUNIT 1; 1.
DR PANTHER; PTHR21573; UNCHARACTERIZED; 1.
DR Pfam; PF07774; EMC1_C; 1.
DR Pfam; PF13360; PQQ_2; 1.
DR SMART; SM00564; PQQ; 4.
DR SUPFAM; SSF50998; Quinoprotein alcohol dehydrogenase-like; 1.
PE 3: Inferred from homology;
KW Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000078512};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..30
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 31..1031
FT /note="ER membrane protein complex subunit 1"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5008276158"
FT TRANSMEM 1003..1021
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 819..1030
FT /note="ER membrane protein complex subunit 1 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF07774"
SQ SEQUENCE 1031 AA; 114052 MW; BF0362F8A87C6FD3 CRC64;
MAPSPPRGLA IWSVALWTIL LALTATTVSA LVESQAGVID WHHRWIGTPH MAANARTVRG
SNSIYVATDK NVVASIKTKS GELLWRQVLR EDETVHAIRA LAGNVVSLTG TKDFHVRLLD
SKTGQPHWDF SPAGEGSSEF GQAVTSTKED GNLIILNEGA NVRKLNSKTG AQIWQWKTEA
GSPTTYFSVV EANGFTGAED VVYVLGLQRG IAAFSLEVVA LESATGKHIK TFNIKSKIDK
VEDVLTLGGG SPLKNGYVAW LEQDYLKILH LGTDKTTQTT LKVLISHVPA FEQLQAPLSF
VDLSLPEGHT QFLLAGTVGE YNDAKAAVLL EIDQSNGKAE IVYDFGERTG FSSWSATIIP
GTEEVAVLRA YRNDPDFAVL EVVNAKERKV TLEQVIPLDF DKFAHFTFAS LEQYTKGQGV
QTRIYFSTMD GSFHAFSDVE SESWYREESL AYAKDVEIVD LPERKLWTQD VNEAGHVKSA
KNESIVAHYM ERLTSHVHQL KDLPAFILSY ANPSSLFTKA PVAVPYSEVQ IGVNNTIQPL
YRDQFGLRKI LIFSTEKGKI VAVDSANKGQ IIWSRFFSMG HDIKNLVIIR HANVRLPPVL
AVIAQTEDGG HNKVVRMYRI NALTGKDHES GNFFFPSASW IPAGYLSAFK LPIEDPDEKT
QVLCLVDDRM HITTFPTTEP VEQAFKALSE DLYFTLENKI GGKKVSGYKA IVSAETDRMD
VEPTWTVPFP DGEEIVALAE KPSYEVMASL GRVLGDRGVL YKYQNPNYAT VVTANKTPKN
GMAPYITVYL IDTVKGSILY QATHENVGAE HKVLATQFEN NVVYTFWSEG ETSTSAKGFQ
AVSLELYESN LRNQRTKSDT FSSFTAEKPH VIAQSFPFSQ AASAIGVTTT KAGISAKDIL
FGLSRHSIMA INQRYLDPRR PTGAPTAMEK EEMLIPYSPI PDDARLYLSY NLEVANVKKI
VTSPTLLEST TVVVAFGQDV FVTRHAPSKT FDILNEDFSK SQLMLTIVAL VVVLFVTKPM
VVNKQLKELW Y
//
