ID A0A197K7R0_9FUNG Unreviewed; 2189 AA.
AC A0A197K7R0;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 24-JAN-2024, entry version 33.
DE SubName: Full=Sec63-domain-containing protein {ECO:0000313|EMBL:OAQ33198.1};
GN ORFNames=K457DRAFT_256504 {ECO:0000313|EMBL:OAQ33198.1};
OS Linnemannia elongata AG-77.
OC Eukaryota; Fungi; Fungi incertae sedis; Mucoromycota; Mortierellomycotina;
OC Mortierellomycetes; Mortierellales; Mortierellaceae; Linnemannia.
OX NCBI_TaxID=1314771 {ECO:0000313|EMBL:OAQ33198.1, ECO:0000313|Proteomes:UP000078512};
RN [1] {ECO:0000313|EMBL:OAQ33198.1, ECO:0000313|Proteomes:UP000078512}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AG-77 {ECO:0000313|EMBL:OAQ33198.1,
RC ECO:0000313|Proteomes:UP000078512};
RG DOE Joint Genome Institute;
RA Uehling J., Gryganskyi A., Hameed K., Tschaplinski T., Misztal P., Wu S.,
RA Desiro A., Vande Pol N., Du Z.-Y., Zienkiewicz A., Zienkiewicz K.,
RA Morin E., Tisserant E., Splivallo R., Hainaut M., Henrissat B., Ohm R.,
RA Kuo A., Yan J., Lipzen A., Nolan M., Labutti K., Barry K., Goldstein A.,
RA Labbe J., Schadt C., Tuskan G., Grigoriev I., Martin F., Vilgalys R.,
RA Bonito G.;
RT "Genome sequencing reveals origins of a unique bacterial endosymbiosis in
RT the earliest lineages of terrestrial Fungi.";
RL Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KV442022; OAQ33198.1; -; Genomic_DNA.
DR STRING; 1314771.A0A197K7R0; -.
DR OrthoDB; 57056at2759; -.
DR Proteomes; UP000078512; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0006397; P:mRNA processing; IEA:UniProt.
DR CDD; cd18019; DEXHc_Brr2_1; 1.
DR CDD; cd18021; DEXHc_Brr2_2; 1.
DR CDD; cd18795; SF2_C_Ski2; 2.
DR Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 2.
DR Gene3D; 2.60.40.150; C2 domain; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 4.
DR Gene3D; 1.10.3380.10; Sec63 N-terminal domain-like domain; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR041094; Brr2_helicase_PWI.
DR InterPro; IPR048863; BRR2_plug.
DR InterPro; IPR035892; C2_domain_sf.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR014756; Ig_E-set.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR004179; Sec63-dom.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR47961; DNA POLYMERASE THETA, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G05260)-RELATED; 1.
DR PANTHER; PTHR47961:SF4; U5 SMALL NUCLEAR RIBONUCLEOPROTEIN HELICASE; 1.
DR Pfam; PF21188; BRR2_plug; 1.
DR Pfam; PF00270; DEAD; 2.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF18149; Helicase_PWI; 1.
DR Pfam; PF02889; Sec63; 2.
DR PIRSF; PIRSF039073; BRR2; 1.
DR SMART; SM00382; AAA; 2.
DR SMART; SM00487; DEXDc; 2.
DR SMART; SM00490; HELICc; 2.
DR SMART; SM00973; Sec63; 2.
DR SUPFAM; SSF81296; E set domains; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 3.
DR SUPFAM; SSF158702; Sec63 N-terminal domain-like; 2.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 2.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 2.
DR PROSITE; PS51194; HELICASE_CTER; 2.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000256|ARBA:ARBA00022806};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000078512}.
FT DOMAIN 519..703
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 741..934
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT DOMAIN 1370..1550
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 1580..1791
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 16..85
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 402..435
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2167..2189
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 43..85
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2189 AA; 248681 MW; 7C41F3D01613BEAA CRC64;
MADKVAKDQQ YQYALNSNLV LHSNRSDNPR RGNEPTGEAE SLYGRIDPKE FGSRAMRDTA
KIDEAKKKKS EPTEKDLERR KKRAEDKALR SAYGYSSVLA ATEDRESGGY RPRTRETRQT
YELILTFVQR YLGDVAHDIV RSAGDIVLEI LHTDTLKDFD KKKGVEEVLG PVDSDQFSVL
LNLGKKITDY APGAEETSTV GQDGEVKNVG DIDEQYGVAV VFDEEEEDED IYSLHSESEH
EDEDTGLDTA QDVVVGGAGK ANQEEEEEAM EVDEDVAVRV GATEGKVDTS KKLQPHQVDA
YWLQRFIATF YKDEIVAQEK TDAAMEIIAS ETINMRDCEN ELMALFDYDK FELVSMLTRN
REVIVWCTRL GKASEQERTE IEANMREIGL DWIIKGLGHQ TGKKSDLRRR GAGQAPTAAG
PTAVLPKEKG PAPTTSAPRQ LIDLDAMAFA QGSHLMSNKS VHVPEGSFRR QKKGYEEVHV
PQPKKPTTDR PLKGKDELPA WIQDCFPDGL NQIQTAVYDV AYGSEENMLL CAPTGAGKTN
CAMLTVLNEI EKHRDPETGV IDKDNFKVVY IAPMKALVQE MVENFGKRLK PFGLSVQELT
GDRQMNKQQI AETQMIVTTP EKWDIITRKA TDRSYTNLVR LIIIDEIHLL HDDRGPVLES
IVARTLRHME QSQELIRLVG LSATLPNYID VATFLRVDTN RGMFHFDGTW RPCPLKQEFI
GITEKKAIKR FQVMNEVTYE KVMEHVVQTE GDQVLIFVHS RKETAKTAQA IRDMALEKDT
IAHFARPDGG AREILLSEAE QASDPALKDI LPYGFATHHA GMTRPDREAV EELFTAGHIK
VLVSTATLAW GVNLPAHTVI IKGTQVYSPE KGRWAELSPQ DVLQMLGRAG RPQFDKFGEG
IIITNHSELQ YYLSLMNQQL PIESQFVTKL ADNLNAEIVL GTIKNRDEAV QWLGYTYLYV
RMLRNPSLYG VSPDDLDDDP YLQKKRVDII HSAATILDKC NMIKYDKRTG KFQGTELGRI
ASHYYISHNS MATYNQHLKP MMSHIELFRV FSLSDEFKYI PVREEEKAEL QKWLEQVPVP
VKESIEEPTA KINVLLQSYI SQLKLEGFAL VSDMVYVTQS SGRILRAIFE ICLRRGWAQL
TRKALDLCKM VEKRQWLSMT PLRQFKGINP ELIKKIERKE FEWVRYFDLS SQEIGELVGV
PKAGKLLERY VHEFPKLDLQ SHVQPLTRSI LKVELTITPD FKWDEKVHGT AEAFWILVED
VDGEMILHQE SFILKQQYAE EEHLMTFTVP LFDPLPPNYF VSIVSDRWLH SETRFPISFK
HLILPEKYPP HTELLDLQSL PVTALRNREF EEIYSQTLSK FNPIQTQTFN TLYTLDDNVF
VGAPTGSGKT ICAEFAMMRQ WNKKPVKGVR GRIVYIAPHQ EVVDARRQEW HAKFGDVQGG
KTILSLTGET SADLKILERG DVILATPGQW DVISRRWKQR KNVQTVQLFI ADELHMIGGD
IGPTYEVIVS RMRYIASQVE SKIRIVALST SLANARDLGE WIGATSHSVF NFHPMVRPLP
LDVHIQSYTI PHFASWMIAM AKPTYTAITT HSPEKPVIVF VPSRKQCRLT VTELLTLCAA
DDTPKRFLHC EEDVLRAHLE HVQDSALASA LEHGIGFFHE ALSKSDKRVV EKLFESGAIQ
VVVASRDTCW GIPLSSYMVV VMGTQYYDGK DHRYADYPTT DVLQMMGRAC RPQEDESSRC
VLMCQSNRKE FYKKFLFEAL PVESHLDHFL HDHFNAEIVT KTIENKQDAV DYLTWTFLYR
RMAQNPNYYN LQGVTHRHLS DHLSELVETT INDLVTSKCI AIEDEMDVSP LNLGMIAAYY
NINFSTVELF SSSLTPTTKL KGLLEIISTA AEYESIPIRH HEDQVLKRIY ERLPVKLSNV
KFNSPHHKAN ILLQAHFSRT QLPADLASDQ ALVVGQVIPL LQACVDVISS NGWLPPALAA
MELAQMSVQA MWDRDSPLKQ IPYMTNERVK RCEAKGVESV FDIQDLEDKD RDAALQVDER
QMRAIAAFVN RYPSIEAEYG IEDENDIKAG QPVVIEVQLE RDGDEDDGEL SSVPAPFFPG
KKDEGWWIVV GDPSTKTLLA IKRITLQRKL RVKLEFVCPR AGNQTYKLYT MCDSFLGCDQ
EFDLELEVGE AEDDSDEEDE EDSDVEMQE
//
