ID A0A197KG64_9FUNG Unreviewed; 559 AA.
AC A0A197KG64;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 08-NOV-2023, entry version 19.
DE SubName: Full=Carotenoid oxygenase {ECO:0000313|EMBL:OAQ36717.1};
GN ORFNames=K457DRAFT_103338 {ECO:0000313|EMBL:OAQ36717.1};
OS Linnemannia elongata AG-77.
OC Eukaryota; Fungi; Fungi incertae sedis; Mucoromycota; Mortierellomycotina;
OC Mortierellomycetes; Mortierellales; Mortierellaceae; Linnemannia.
OX NCBI_TaxID=1314771 {ECO:0000313|EMBL:OAQ36717.1, ECO:0000313|Proteomes:UP000078512};
RN [1] {ECO:0000313|EMBL:OAQ36717.1, ECO:0000313|Proteomes:UP000078512}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AG-77 {ECO:0000313|EMBL:OAQ36717.1,
RC ECO:0000313|Proteomes:UP000078512};
RG DOE Joint Genome Institute;
RA Uehling J., Gryganskyi A., Hameed K., Tschaplinski T., Misztal P., Wu S.,
RA Desiro A., Vande Pol N., Du Z.-Y., Zienkiewicz A., Zienkiewicz K.,
RA Morin E., Tisserant E., Splivallo R., Hainaut M., Henrissat B., Ohm R.,
RA Kuo A., Yan J., Lipzen A., Nolan M., Labutti K., Barry K., Goldstein A.,
RA Labbe J., Schadt C., Tuskan G., Grigoriev I., Martin F., Vilgalys R.,
RA Bonito G.;
RT "Genome sequencing reveals origins of a unique bacterial endosymbiosis in
RT the earliest lineages of terrestrial Fungi.";
RL Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Fe(2+); Xref=ChEBI:CHEBI:29033;
CC Evidence={ECO:0000256|PIRSR:PIRSR604294-1};
CC Note=Binds 1 Fe(2+) ion per subunit. {ECO:0000256|PIRSR:PIRSR604294-1};
CC -!- SIMILARITY: Belongs to the carotenoid oxygenase family.
CC {ECO:0000256|ARBA:ARBA00006787}.
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DR EMBL; KV442011; OAQ36717.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A197KG64; -.
DR STRING; 1314771.A0A197KG64; -.
DR OrthoDB; 294919at2759; -.
DR Proteomes; UP000078512; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:InterPro.
DR InterPro; IPR004294; Carotenoid_Oase.
DR PANTHER; PTHR10543; BETA-CAROTENE DIOXYGENASE; 1.
DR PANTHER; PTHR10543:SF24; CAROTENOID ISOMEROOXYGENASE; 1.
DR Pfam; PF03055; RPE65; 1.
PE 3: Inferred from homology;
KW Iron {ECO:0000256|ARBA:ARBA00023004, ECO:0000256|PIRSR:PIRSR604294-1};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW ECO:0000256|PIRSR:PIRSR604294-1};
KW Reference proteome {ECO:0000313|Proteomes:UP000078512}.
FT BINDING 218
FT /ligand="Fe cation"
FT /ligand_id="ChEBI:CHEBI:24875"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000256|PIRSR:PIRSR604294-1"
FT BINDING 274
FT /ligand="Fe cation"
FT /ligand_id="ChEBI:CHEBI:24875"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000256|PIRSR:PIRSR604294-1"
FT BINDING 343
FT /ligand="Fe cation"
FT /ligand_id="ChEBI:CHEBI:24875"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000256|PIRSR:PIRSR604294-1"
FT BINDING 550
FT /ligand="Fe cation"
FT /ligand_id="ChEBI:CHEBI:24875"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000256|PIRSR:PIRSR604294-1"
SQ SEQUENCE 559 AA; 62175 MW; 9AC03F5936769803 CRC64;
MTKATDAPVN NGPWPYAAGY DNCPEVLDPI SLSVKGTIPP WLEGALYRSG PGTYDLKTES
GKDVHIQHWF DGLAQVHRYE IQKGGQVSYR SRNTSNDLRA EYIKEEKVTG VTFCQRDPCK
TIFNKFFTTF KTAALGGGHV LGGTNTNVAV IPTPNFPGLM DKKDGSKKSG NPNIRNLIMT
TDGNAIQELD PVTLEPKGLF SYGAIDDSLL ASNLAPAHPC VDPETGDYFT VLLTFGPTAV
YKVVRIRQSV KGPAREPDLD VLAEIQSPRP TYMHSFCLTK RYVVVTHWQC DFAAWGVSVL
WTGNAWESFK NHDPNVKAQF YVVDRQHGRH VATFECDPYY AFHAVNAWDE GDDIVLDLAS
YKDHTVIGDY YIDNLRNEAS GIPPQQAVLR RYRLSAISKQ ASLSNLNRKQ PPTPVPATID
FQLDESINFE LPSINPSRYL HPYRYAFGVN RSGLNKTLIY DRIIKVDLAK VQQGDMSGSA
TFWVQDQCTP SEPVFVPTPN ATDEDDGVLL SIVLDGRRRT GFLLVLDAKT LTEIARADMP
EGKVAPHNFH GMFIPNLVN
//
