ID A0A199UE07_ANACO Unreviewed; 1312 AA.
AC A0A199UE07;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 24-JAN-2024, entry version 26.
DE SubName: Full=Varicose-related protein {ECO:0000313|EMBL:OAY63102.1};
GN ORFNames=ACMD2_11578 {ECO:0000313|EMBL:OAY63102.1};
OS Ananas comosus (Pineapple) (Ananas ananas).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Bromeliaceae;
OC Bromelioideae; Ananas.
OX NCBI_TaxID=4615 {ECO:0000313|EMBL:OAY63102.1, ECO:0000313|Proteomes:UP000092600};
RN [1] {ECO:0000313|EMBL:OAY63102.1, ECO:0000313|Proteomes:UP000092600}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. MD2 {ECO:0000313|Proteomes:UP000092600};
RC TISSUE=Leaf {ECO:0000313|EMBL:OAY63102.1};
RX PubMed=27374615; DOI=10.1093/dnares/dsw026;
RA Redwan R.M., Saidin A., Kumar S.V.;
RT "The draft genome of MD-2 pineapple using hybrid error correction of long
RT reads.";
RL DNA Res. 0:0-0(2016).
CC -!- SUBCELLULAR LOCATION: Cytoplasm, P-body
CC {ECO:0000256|ARBA:ARBA00004201}.
CC -!- SIMILARITY: Belongs to the WD repeat EDC4 family.
CC {ECO:0000256|ARBA:ARBA00009639}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OAY63102.1}.
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DR EMBL; LSRQ01008391; OAY63102.1; -; Genomic_DNA.
DR STRING; 4615.A0A199UE07; -.
DR Proteomes; UP000092600; Unassembled WGS sequence.
DR GO; GO:0000932; C:P-body; IEA:UniProtKB-SubCell.
DR GO; GO:0031087; P:deadenylation-independent decapping of nuclear-transcribed mRNA; IEA:InterPro.
DR Gene3D; 1.10.220.100; conserved c-terminal region of ge- 1; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR InterPro; IPR045152; EDC4-like.
DR InterPro; IPR049404; EDC4_C.
DR InterPro; IPR044938; EDC4_C_sf.
DR InterPro; IPR032401; EDC4_WD40.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR15598; ENHANCER OF MRNA-DECAPPING PROTEIN 4; 1.
DR PANTHER; PTHR15598:SF5; ENHANCER OF MRNA-DECAPPING PROTEIN 4; 1.
DR Pfam; PF21289; EDC4_C; 1.
DR Pfam; PF16529; Ge1_WD40; 1.
DR SMART; SM00320; WD40; 3.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 2.
DR PROSITE; PS50294; WD_REPEATS_REGION; 2.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Reference proteome {ECO:0000313|Proteomes:UP000092600};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT DOMAIN 170..483
FT /note="Enhancer of mRNA-decapping protein 4 WD40 repeat
FT region"
FT /evidence="ECO:0000259|Pfam:PF16529"
FT REPEAT 217..259
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 336..378
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT DOMAIN 1180..1283
FT /note="Enhancer of mRNA-decapping protein 4 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF21289"
FT REGION 1..64
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 108..149
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 553..582
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 608..670
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 758..779
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 793..872
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..36
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 111..133
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 555..571
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 620..670
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 809..827
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 850..872
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1312 AA; 141935 MW; 7B2272C9981DD446 CRC64;
MASSPGTPTT SAPFELSKLL KTPTTNTTTT TTATTTSSPP TPPPSASSAA SPPPLSSAGP
FSYAPATPPI LHHLHPFLHR PAATPNPNPN PIPGARITQH LHAASPIESA VSQPPPFPLN
PSTPPPPAPS PARVLSGKKP RGRRLGGGER AVHDVDWRMQ GEAEPPQLEV TPITKYTSDP
DLVLGRQIAV NRSYIVYGLK LGNIRVLNIN TALRSLLRGH TQRVTDMAFF AEDVQLLASA
SADGRVFIWK IDEGPDKENK PQITAKIVTA IQIVGDGESY HPRICWHSHK QEILFVGIGS
IVLKIDTIKV GRGKGFSAEE PLKCPIEKLI DGVQLIGKHD GDVTDLSISQ WMTTRLASAS
KDGTVKIWDE RKAVALSTLR PHDGQAVNSV AFLTSPDRPD HINLVTAGPL SREVKIWAST
SDEGWLLPSD SESWRCNQTL ELRSTSESQL EEAFFNQVVI LPRTSLLILA NAKKNAIYAI
HIDYSPCPAS TRMDYIADFT VAMPILSLTA NSDCLDGEQV VQLYCVQTMA IQQYALDLAL
CLPPPIDNAG IKRDPSYSHI SNKSNSGGVA EPSLGSPLLK PSPIDCSNEK TITSTLSADA
SATEITTSPV PLLFGPSGRL PSLKSSSQGS EQGQSLGDHD TLITSASDVS SVNNKSGKDE
TSAGQNQTDT SFVPATHVMF KVGGNTTHLV TPSEILSGAI SSSEDNHVNQ GLKCEEEKIQ
GVVADNNNER AGVEVKVVEK SRSNENLELD GRKIPEVLQE ENNEKLPKSL ESNSQMVNRG
PLLTDTHRVE ESRFAEDSAI SESLEHSSVT GWEADKDSSK DMPEKFEESA VATASDSLLF
DKEEQKVKKS QVPSTQSPSS SPYNSTDSVN EPGNREIVFL SDVALPQISA VQDALNQLIT
MQKDMQMKLS DMVAVPVAKE GKRIEAALGR SMEKSVKANF DALWARFQEE NAKREKIEKD
RLQHIANVIT NCINKDLPSL LERALKKEIS ALGPIVARAL TPVIEKAISS AVADSFQRGV
VDKAVNQLDK SLNSKLEVSL TRQIQTQFQT SGKQALQDAL KSSLESSVIP AFEQACKSTF
EQIDAAFRKG MSERATAAQQ QLEAAHTPLA IALRDAINSA SSITQSFTAE LVDGQRKLLA
LVAAGNTKAL NPIAVQTNNG LIAARPEMAE TPLDPKRELS RLISEHKYEE AFMSALQRSD
VSIVSWLCSQ VDLRKICSTV PLCLNQGVLL ALLQQLACDI ANDTSRKVAW MTDVAVAINP
SDPMISLHVR PIFEQVYNIL GHQRSLPTVT PAESSNIRLL MHVVNSVLLS CK
//
