ID A0A199UFB0_ANACO Unreviewed; 1133 AA.
AC A0A199UFB0;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=non-specific serine/threonine protein kinase {ECO:0000256|ARBA:ARBA00012513};
DE EC=2.7.11.1 {ECO:0000256|ARBA:ARBA00012513};
GN ORFNames=ACMD2_17119 {ECO:0000313|EMBL:OAY63401.1};
OS Ananas comosus (Pineapple) (Ananas ananas).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Bromeliaceae;
OC Bromelioideae; Ananas.
OX NCBI_TaxID=4615 {ECO:0000313|EMBL:OAY63401.1, ECO:0000313|Proteomes:UP000092600};
RN [1] {ECO:0000313|EMBL:OAY63401.1, ECO:0000313|Proteomes:UP000092600}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. MD2 {ECO:0000313|Proteomes:UP000092600};
RC TISSUE=Leaf {ECO:0000313|EMBL:OAY63401.1};
RX PubMed=27374615; DOI=10.1093/dnares/dsw026;
RA Redwan R.M., Saidin A., Kumar S.V.;
RT "The draft genome of MD-2 pineapple using hybrid error correction of long
RT reads.";
RL DNA Res. 0:0-0(2016).
CC -!- SIMILARITY: Belongs to the protein kinase superfamily. Ser/Thr protein
CC kinase family. {ECO:0000256|ARBA:ARBA00008684}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OAY63401.1}.
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DR EMBL; LSRQ01008346; OAY63401.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A199UFB0; -.
DR STRING; 4615.A0A199UFB0; -.
DR Proteomes; UP000092600; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd14066; STKc_IRAK; 1.
DR Gene3D; 3.30.1490.310; -; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR045381; BRI1_island_dom.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR025875; Leu-rich_rpt_4.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR013210; LRR_N_plant-typ.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR017441; Protein_kinase_ATP_BS.
DR InterPro; IPR001245; Ser-Thr/Tyr_kinase_cat_dom.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR PANTHER; PTHR48005; LEUCINE RICH REPEAT KINASE 2; 1.
DR PANTHER; PTHR48005:SF88; OS02G0154200 PROTEIN; 1.
DR Pfam; PF20141; Island; 1.
DR Pfam; PF00560; LRR_1; 7.
DR Pfam; PF12799; LRR_4; 1.
DR Pfam; PF13855; LRR_8; 2.
DR Pfam; PF08263; LRRNT_2; 1.
DR Pfam; PF07714; PK_Tyr_Ser-Thr; 1.
DR PRINTS; PR00019; LEURICHRPT.
DR SMART; SM00369; LRR_TYP; 7.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF52058; L domain-like; 2.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR SUPFAM; SSF52047; RNI-like; 1.
DR PROSITE; PS51450; LRR; 1.
DR PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU10141};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:OAY63401.1};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU10141}; Reference proteome {ECO:0000313|Proteomes:UP000092600};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Serine/threonine-protein kinase {ECO:0000256|ARBA:ARBA00022527};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..1133
FT /note="non-specific serine/threonine protein kinase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5008285199"
FT TRANSMEM 753..777
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 838..1116
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT BINDING 867
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10141"
SQ SEQUENCE 1133 AA; 123769 MW; F9F888C4A30B7ABA CRC64;
MDTFYLLLLL LLFLFEYSAP SSTVDRKQEA LSSMKRDAEA LLRFKSSVHD PKGFLSNWQV
KYRSPCSWNG VLCTTQGRAT QLNLTRCDLS GALSLYALSP VDELSILDLS HNPSLYINTT
SLFQLPLALT QLDLSSSGLT GLLPEPLVTS YPNLTYLNLS HNNITGSLPS NFLSKSQNLQ
VLDLSFNNLS GSASNLSFEF PCKSLIYFDL SVNYISDEIP FALTSCANLK TLNLSFNSLI
GEIPESFSEL RGLESLDLSN NHLSGSIPYG LGNSCGSLQE LKISTNNISG SIPSSFSSCY
SLRSIDLANN NLSGPFPNDV LQNLFSLETL LVSNNFISGP FPSSISSCKH LRIADFSSNK
LVGDLPPSVC SSPSSLEELR IPDNSITGQI PSDLSNCSQL RVIDLSINYL RGPIPKELGN
LYSLEHLMLW FNGLQGRIPQ ELGQCSKLRT LILNNNLIEG EIPIQLFNCV NLEWVSLTSN
VISGKIPAEF GLLSRLAVLQ LANNSLSGEI PEALGNCSSL MWLDLNSNKL TGEIPARLGR
QLGAKALSGI LSGNTLAFVR NVGNSCKGVG GLLEFAGIRP ERLLQVPTLK TCDFTRLYSG
AALSDWTHYQ TLEYLDLSYN DLSGEIPTEF GDMVVLQVLD LARNNLSGEI PDSLGRLRNL
GVFDASRNQL QGRIPDSFSN LSFLVQIDLS DNNLTGPIPS RGQLSTLPAS QYKNNPGLCG
VPLPPCEAPT SIPTAADFDG KGGERRRSSA MAWANSVILG VLVSVASLCI IVIWAIAVRA
RRREKEEAKM LDSLQANECA TTWKIGKEKE PLSINVATFQ RQLRKLTFSQ LIEATNGFST
ASLIGCGGFG EVFKATLRDG SCVAIKKLIH LSYQGDREFM AEMETLGKIK HKNLVPLLGY
CKIGEERLLV YEYMAHGSLE DALHGKKRRL TWGERKKIAL GAAKGLCFLH HNCIPHIIHR
DMKSSNVLLD GEMEARVADF GMARLISALD THLSVSTLAG TPGYVPPEYY QSFRCTAKGD
VYSFGVVMLE LVTGRRPTDK EDFGDSNLVG WVKEKAMVRE GNCREVFDEE VVRENGGEEE
QEKEMARFLE IALRCVDELL SKRPNMTQVV AMLRQLCSGG GGGGGGEGEG DGA
//
