ID A0A199V6K1_ANACO Unreviewed; 341 AA.
AC A0A199V6K1;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Senescence-specific cysteine protease SAG39 {ECO:0000313|EMBL:OAY72694.1};
GN ORFNames=ACMD2_25817 {ECO:0000313|EMBL:OAY72694.1};
OS Ananas comosus (Pineapple) (Ananas ananas).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Bromeliaceae;
OC Bromelioideae; Ananas.
OX NCBI_TaxID=4615 {ECO:0000313|EMBL:OAY72694.1, ECO:0000313|Proteomes:UP000092600};
RN [1] {ECO:0000313|EMBL:OAY72694.1, ECO:0000313|Proteomes:UP000092600}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. MD2 {ECO:0000313|Proteomes:UP000092600};
RC TISSUE=Leaf {ECO:0000313|EMBL:OAY72694.1};
RX PubMed=27374615; DOI=10.1093/dnares/dsw026;
RA Redwan R.M., Saidin A., Kumar S.V.;
RT "The draft genome of MD-2 pineapple using hybrid error correction of long
RT reads.";
RL DNA Res. 0:0-0(2016).
CC -!- SIMILARITY: Belongs to the peptidase C1 family.
CC {ECO:0000256|ARBA:ARBA00008455}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OAY72694.1}.
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DR EMBL; LSRQ01003004; OAY72694.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A199V6K1; -.
DR STRING; 4615.A0A199V6K1; -.
DR Proteomes; UP000092600; Unassembled WGS sequence.
DR GO; GO:0008234; F:cysteine-type peptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd02248; Peptidase_C1A; 1.
DR Gene3D; 3.90.70.10; Cysteine proteinases; 1.
DR InterPro; IPR038765; Papain-like_cys_pep_sf.
DR InterPro; IPR025661; Pept_asp_AS.
DR InterPro; IPR000169; Pept_cys_AS.
DR InterPro; IPR025660; Pept_his_AS.
DR InterPro; IPR013128; Peptidase_C1A.
DR InterPro; IPR000668; Peptidase_C1A_C.
DR InterPro; IPR039417; Peptidase_C1A_papain-like.
DR InterPro; IPR013201; Prot_inhib_I29.
DR PANTHER; PTHR12411:SF741; CATHEPSIN K; 1.
DR PANTHER; PTHR12411; CYSTEINE PROTEASE FAMILY C1-RELATED; 1.
DR Pfam; PF08246; Inhibitor_I29; 1.
DR Pfam; PF00112; Peptidase_C1; 1.
DR PRINTS; PR00705; PAPAIN.
DR SMART; SM00848; Inhibitor_I29; 1.
DR SMART; SM00645; Pept_C1; 1.
DR SUPFAM; SSF54001; Cysteine proteinases; 1.
DR PROSITE; PS00640; THIOL_PROTEASE_ASN; 1.
DR PROSITE; PS00139; THIOL_PROTEASE_CYS; 1.
DR PROSITE; PS00639; THIOL_PROTEASE_HIS; 1.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Hydrolase {ECO:0000313|EMBL:OAY72694.1};
KW Protease {ECO:0000313|EMBL:OAY72694.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000092600};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..26
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 27..341
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5018532859"
FT DOMAIN 39..95
FT /note="Cathepsin propeptide inhibitor"
FT /evidence="ECO:0000259|SMART:SM00848"
FT DOMAIN 124..340
FT /note="Peptidase C1A papain C-terminal"
FT /evidence="ECO:0000259|SMART:SM00645"
SQ SEQUENCE 341 AA; 36985 MW; A673AB571809BE21 CRC64;
MAFPTIFQGR CMALLVLTLW ASFASASREL GEMSMLERHE RWMAQHGKAY EDAAEKERRF
EIFKSNFELI QTFNKGNHKF RLGLNQFADL TNDEFRATHN GFKPKSGAAA STAKRFRYEN
VTAVPASMDW RAKGAVTPVK DQGQCGCCWA FSAVAATEGI TKLATGKLVS LSEQELVDCD
VHGDDQGCDG GLMDSAFDFI VKNRGLTTEA NYPYKGADGK CNARKAAAAA SISGYEDVPA
NHESALLKAV ARQPVSVAID AGGFAFQMYK GGVFTGDCGT DLDHGVTAVG YGVASDGTKY
WLIKNSWGSS WGENGYIRME RDVNSKEGLC GIAMEASYPT A
//
