ID   A0A199VA06_ANACO        Unreviewed;       413 AA.
AC   A0A199VA06;
DT   05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2016, sequence version 1.
DT   27-MAR-2024, entry version 34.
DE   RecName: Full=U-box domain-containing protein {ECO:0000256|RuleBase:RU369093};
DE            EC=2.3.2.27 {ECO:0000256|RuleBase:RU369093};
DE   AltName: Full=RING-type E3 ubiquitin transferase PUB {ECO:0000256|RuleBase:RU369093};
GN   Name=LOC109715788 {ECO:0000313|RefSeq:XP_020096550.1};
GN   ORFNames=ACMD2_01311 {ECO:0000313|EMBL:OAY73942.1};
OS   Ananas comosus (Pineapple) (Ananas ananas).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Bromeliaceae;
OC   Bromelioideae; Ananas.
OX   NCBI_TaxID=4615 {ECO:0000313|EMBL:OAY73942.1, ECO:0000313|Proteomes:UP000092600};
RN   [1] {ECO:0000313|EMBL:OAY73942.1, ECO:0000313|Proteomes:UP000092600}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. MD2 {ECO:0000313|Proteomes:UP000092600};
RC   TISSUE=Leaf {ECO:0000313|EMBL:OAY73942.1};
RX   PubMed=27374615; DOI=10.1093/dnares/dsw026;
RA   Redwan R.M., Saidin A., Kumar S.V.;
RT   "The draft genome of MD-2 pineapple using hybrid error correction of long
RT   reads.";
RL   DNA Res. 0:0-0(2016).
RN   [2] {ECO:0000313|RefSeq:XP_020096550.1}
RP   IDENTIFICATION.
RC   TISSUE=Leaf {ECO:0000313|RefSeq:XP_020096550.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- FUNCTION: Functions as an E3 ubiquitin ligase.
CC       {ECO:0000256|RuleBase:RU369093}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine +
CC         [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-
CC         cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.;
CC         EC=2.3.2.27; Evidence={ECO:0000256|ARBA:ARBA00000900,
CC         ECO:0000256|RuleBase:RU369093};
CC   -!- PATHWAY: Protein modification; protein ubiquitination.
CC       {ECO:0000256|ARBA:ARBA00004906, ECO:0000256|RuleBase:RU369093}.
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DR   EMBL; LSRQ01002555; OAY73942.1; -; Genomic_DNA.
DR   RefSeq; XP_020096550.1; XM_020240961.1.
DR   STRING; 4615.A0A199VA06; -.
DR   EnsemblPlants; Aco020835.1.mrna1; Aco020835.1.mrna1.cds1; Aco020835.1.path1.
DR   GeneID; 109715788; -.
DR   Gramene; Aco020835.1.mrna1; Aco020835.1.mrna1.cds1; Aco020835.1.path1.
DR   OrthoDB; 5489991at2759; -.
DR   UniPathway; UPA00143; -.
DR   Proteomes; UP000092600; Unassembled WGS sequence.
DR   Proteomes; UP000515123; Linkage group 9.
DR   GO; GO:0061630; F:ubiquitin protein ligase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniRule.
DR   CDD; cd16664; RING-Ubox_PUB; 1.
DR   Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 2.
DR   Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR045185; PUB22/23/24-like.
DR   InterPro; IPR045210; RING-Ubox_PUB.
DR   InterPro; IPR003613; Ubox_domain.
DR   InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR   PANTHER; PTHR22849:SF23; RING-TYPE E3 UBIQUITIN TRANSFERASE; 1.
DR   PANTHER; PTHR22849; WDSAM1 PROTEIN; 1.
DR   Pfam; PF04564; U-box; 1.
DR   SMART; SM00504; Ubox; 1.
DR   SUPFAM; SSF48371; ARM repeat; 1.
DR   SUPFAM; SSF57850; RING/U-box; 1.
DR   PROSITE; PS51698; U_BOX; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000092600};
KW   Transferase {ECO:0000256|RuleBase:RU369093};
KW   Ubl conjugation pathway {ECO:0000256|RuleBase:RU369093}.
FT   DOMAIN          5..80
FT                   /note="U-box"
FT                   /evidence="ECO:0000259|PROSITE:PS51698"
SQ   SEQUENCE   413 AA;  45713 MW;  9B6470E2B9A081F2 CRC64;
     MEEEEAPLLF RCPISMDLMA DPVTIATGVS YERKNIEKWL LTYKRSTCPA TMQHLDTLDL
     TPNHTLKRLI STWLDKQSAN PNTTDQRSTG DLISRLTDIE SSPFKVNSLR SLKSMLETSE
     EMQNRLLRSG GIEVLARIMS QATAAADITD FSAFRACEEA AGVVSVLPLY DEASSSAAEI
     LLRPKCVKPM TAILQRGSAE ARIATMDILV KMARINRKWI DALGDDQNTE VLKSLLDLLS
     DEISTRKLSS LSLEVLLSIV AGSKGGRSRA VDVGAVPVLI ELLPDADRHT CERILLLLKR
     LCECPEGRSA FAEHAMGVAA VAKKILRVSD GGTKVGVKIL WLVCSFFPTE KVLDEMMASG
     AVKKLLALVH VDGRPSTKEK AIKIIRMHGM TWRQYPCFPG ELRDYLRLMH ETC
//