ID A0A199VPX9_ANACO Unreviewed; 2558 AA.
AC A0A199VPX9;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE SubName: Full=Putative disease resistance protein RGA4 {ECO:0000313|EMBL:OAY78760.1};
GN ORFNames=ACMD2_08451 {ECO:0000313|EMBL:OAY78760.1};
OS Ananas comosus (Pineapple) (Ananas ananas).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Bromeliaceae;
OC Bromelioideae; Ananas.
OX NCBI_TaxID=4615 {ECO:0000313|EMBL:OAY78760.1, ECO:0000313|Proteomes:UP000092600};
RN [1] {ECO:0000313|EMBL:OAY78760.1, ECO:0000313|Proteomes:UP000092600}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. MD2 {ECO:0000313|Proteomes:UP000092600};
RC TISSUE=Leaf {ECO:0000313|EMBL:OAY78760.1};
RX PubMed=27374615; DOI=10.1093/dnares/dsw026;
RA Redwan R.M., Saidin A., Kumar S.V.;
RT "The draft genome of MD-2 pineapple using hybrid error correction of long
RT reads.";
RL DNA Res. 0:0-0(2016).
CC -!- SIMILARITY: Belongs to the disease resistance NB-LRR family.
CC {ECO:0000256|ARBA:ARBA00008894}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OAY78760.1}.
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DR EMBL; LSRQ01001221; OAY78760.1; -; Genomic_DNA.
DR STRING; 4615.A0A199VPX9; -.
DR Proteomes; UP000092600; Unassembled WGS sequence.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0006952; P:defense response; IEA:UniProtKB-KW.
DR GO; GO:0051707; P:response to other organism; IEA:UniProt.
DR Gene3D; 1.20.5.4130; -; 3.
DR Gene3D; 1.10.8.430; Helical domain of apoptotic protease-activating factors; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 4.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR042197; Apaf_helical.
DR InterPro; IPR044974; Disease_R_plants.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR041118; Rx_N.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR23155; DISEASE RESISTANCE PROTEIN RP; 1.
DR PANTHER; PTHR23155:SF1237; DISEASE RESISTANCE RPP13-LIKE PROTEIN 1-RELATED; 1.
DR Pfam; PF00560; LRR_1; 1.
DR Pfam; PF00931; NB-ARC; 3.
DR Pfam; PF18052; Rx_N; 3.
DR PRINTS; PR00364; DISEASERSIST.
DR SMART; SM00369; LRR_TYP; 7.
DR SUPFAM; SSF52058; L domain-like; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 3.
DR SUPFAM; SSF52047; RNI-like; 2.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Plant defense {ECO:0000256|ARBA:ARBA00022821};
KW Reference proteome {ECO:0000313|Proteomes:UP000092600};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 272..345
FT /note="Disease resistance N-terminal"
FT /evidence="ECO:0000259|Pfam:PF18052"
FT DOMAIN 404..624
FT /note="NB-ARC"
FT /evidence="ECO:0000259|Pfam:PF00931"
FT DOMAIN 1249..1330
FT /note="Disease resistance N-terminal"
FT /evidence="ECO:0000259|Pfam:PF18052"
FT DOMAIN 1435..1660
FT /note="NB-ARC"
FT /evidence="ECO:0000259|Pfam:PF00931"
FT DOMAIN 2265..2341
FT /note="Disease resistance N-terminal"
FT /evidence="ECO:0000259|Pfam:PF18052"
FT DOMAIN 2429..2500
FT /note="NB-ARC"
FT /evidence="ECO:0000259|Pfam:PF00931"
SQ SEQUENCE 2558 AA; 288931 MW; 6FF3D2BA6DB42F5D CRC64;
MVSSSLGTYL PYLRSVKFDG QLPYLRYLRI KNALAIVTIG PELLGNGVGD GVHTATAFPK
LEFLYMIDMP NWEEWSLVGS ETGNSSSCSL RVMPRLEELR VIDCPKLRAL PKGLQQLRIL
KVELAHSLSV IEDFPFITEL RINTNNNMER VSNLPGLKKL TIWDTPALKC VDSLVALQYL
ELQDYSMESL PEWLLRLVQQ CTHLHDKNPQ LVIRCSAAVI QRCLKGGPDW PIIECFSRVN
TYTEDRSAYL EYAKQIGTNT QMEALEALFG NCSQKLSALI QDEVAMILGV KEELGKLQRR
MKRIDGALKK VGRERTEDTA WLNELQSILH EANDVFDDLR YEGGKLLDNE LPSASSVLSI
LCCLPMFSFF NLIRVHHNLA NRIRALNNRI DEIAKDQWIL NVELVRSESM GGIGKTMLAQ
KVYNSKRIED NFQVRIWICV TQKYSDVRLL QEITRKAGGS HGSAERVSEL LPILRQTLGG
RSIFLVLDDV WRSDVWTDLL RNPLQNGAAR GRVLVTTRDP NVTMRMGAKH VHQVKKMSVD
SGWELLCKRT YLEEGEEDVQ SLRSVGVQIV NKCGGLPLAI KLIAGLLTTK KKSRKEWEKV
LRSNAWSMSK LPEEFRGALY LSYDDLPSHL KPCFLSLCLY PEDDGVYLWD LRRMWVAEGF
VNQEEGLIME ELADQYYFEL IRRSLLQPDP ICGDQRMCKV HDVLRSLAQY LSQSESYYGD
PQSLDSTAIS KLRRLSIAQS REIVTIPGLE TEQLRLRTLL LFMSPPRIPH NLFSRFPYLQ
VLLLNGKGIE CIPDSVGNLI HLRLLDLDRT SITKLPDSIG LLRNLQTLNL QHCQFLNTLP
GSITHLCSLR RLGLYGTPLR SVPEGIGRLQ LLNDLTGFII NAGDSCNTEQ NSWDLEELKS
LCQLRWLQLS ILGGKRNANS MQTTDDLIDQ LLTVTHPRNR VSILEDKSFL KCLFISCTPQ
TERVEVPLYT QEEISRIEDT FEKLRPPTCL EDLLICNFYG HQFSSWMVSS SLGTYLPYLT
YAVFIGLPLC SQLPPLGQLP HLRLLSIEDA LAIVTISSEL LGNGVGDAVH AAIAFPKLEL
LFMMKMPNWE EWSLVGSETG NSSSFSLRVM PRLEQLHVAD CPKLRALPKG LQQLRALRIL
DVERAHSLSV IEDFLFITEL KLEMNNGIEM VSNLPALKKL IIWDSPALKC VDNLVALQYL
ELQDYSMESL PEWLFRLVQQ RVHLQFVMRC SATVIQRCLR GGPDWPIIEC FSRKLAALIH
DKAAAILGVK EELGKLQRRM DRIDCALKDA GWRRTDKDAT TATNCWLSEL KSILHEASDV
FDDCRSEAGK LLDNELPSAS SGLSILHRIP LISNFSSVLL VRNKLADRIR KLNDRIDEVG
KDGWILNLEP VKPEGRAEST SYTRETCEIV EADVVGREIK DATGRLADVI VTNDRRNFQV
TAVTGMGGIG KTTLAQKVYN NPRIGDNFQV RIWICVTQKY SDVRLLQEIT RKAGGSHGSA
ERVSELLPIL SWTLGGRSIF LVLDDGWQSD VWTDLLRNPL QNGAASGCVL VTTRDQNVAM
RMGAKHIHRV EKMSVDSGWE LLCKKTYLEE GGEDAQSLRS VGVQIVDKCG GLPLAIKVIA
GVLTTKEKSR KEWERVLKSN AWSMSELPEE FRGALYLSYD DLPPHLKQCF LSDDVHYIYD
LLRMWAAEGF VNQVEGLIME ELAEQYYFEL IRRSLLQPDP RYVDQRRCEV HDLLRSLAQY
LSQGESYYGD PESLDATAIS KLCRLSIAQS REIVTIPGPE TEQLRLRTLL LIEIPYLQVL
ILNGKGIECI PDSVGSLIHL RLLDLNGTNI SKLPDSIGFL TNLQTLNLQD CKFLNTLPRG
ITRLCSLRRL GLFGTPLRSV PEGIGRLQLL NDLQGFIINA DDSCNTEQNC WDLEELKSLR
QLRWLRLHIL EGKRNANSMQ PTDDTIDQVR TAAPPGNRAF VLANKAFLKK LAVSCTPQTG
SAEAPLYTEE EISKVEDTLE KLHPPRCLEA LSIGNFCGQQ LPSWILSSSL GTYLPYLTYV
SFIGLPLCSQ LPPVGQLPHL RYLEFKNAFA IVTIGPELLS NGVCDGVHTA TAFPKLEFLF
ITDMPNWEEW SLVGSETGNS LSCSLQVMPR PEVLHVIGCP KLRALPKGLQ HLRALRILRA
TMAHSLSVIE DFPFITELQI NGNYNMETKL TIWDSPALKC VDNLVALQYL ELQDYSMESL
PKWLLRQVQQ RVHVHLHDNN LQLVMHCSAA VIQRCLKGGP DWPIIERFSR KLSALIQDEV
AMIRGVKEEL GKLQRRMKRI DGALKKVGRE RTEDTAWMNE LQSILHEAND VFDELRYEGG
KLLDNELPSA SSSGPSKLCG LPMFSCFNLI RVRHNLANRI RALNSRINEV ATDQWILNLK
SEGREASALH SRETCEIMEA DVVGREIEDA TDRLADMIVT NSRGNFQVIA VAGMGGIGKT
TLAQKVYNNS RIGENFQVRI WICVTEKYSD VRLLHEIIGK AEGSHGSADG FPNCSLFLAG
LLEGGASFSF WMMYGDRTYG LIYFEIRCKM EQLADVFW
//
