ID A0A199WA14_ANACO Unreviewed; 943 AA.
AC A0A199WA14;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=ACMD2_05497 {ECO:0000313|EMBL:OAY86071.1};
OS Ananas comosus (Pineapple) (Ananas ananas).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Bromeliaceae;
OC Bromelioideae; Ananas.
OX NCBI_TaxID=4615 {ECO:0000313|EMBL:OAY86071.1, ECO:0000313|Proteomes:UP000092600};
RN [1] {ECO:0000313|EMBL:OAY86071.1, ECO:0000313|Proteomes:UP000092600}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. MD2 {ECO:0000313|Proteomes:UP000092600};
RC TISSUE=Leaf {ECO:0000313|EMBL:OAY86071.1};
RX PubMed=27374615; DOI=10.1093/dnares/dsw026;
RA Redwan R.M., Saidin A., Kumar S.V.;
RT "The draft genome of MD-2 pineapple using hybrid error correction of long
RT reads.";
RL DNA Res. 0:0-0(2016).
CC -!- FUNCTION: Cytokinin receptor related to bacterial two-component
CC regulators. Functions as a histidine kinase and transmits the stress
CC signal to a downstream MAPK cascade. {ECO:0000256|ARBA:ARBA00002427}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OAY86071.1}.
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DR EMBL; LSRQ01000011; OAY86071.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A199WA14; -.
DR STRING; 4615.A0A199WA14; -.
DR Proteomes; UP000092600; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:EnsemblPlants.
DR GO; GO:0004673; F:protein histidine kinase activity; IEA:UniProtKB-EC.
DR GO; GO:0043424; F:protein histidine kinase binding; IEA:EnsemblPlants.
DR GO; GO:0071215; P:cellular response to abscisic acid stimulus; IEA:EnsemblPlants.
DR GO; GO:0070417; P:cellular response to cold; IEA:EnsemblPlants.
DR GO; GO:0016036; P:cellular response to phosphate starvation; IEA:EnsemblPlants.
DR GO; GO:0071329; P:cellular response to sucrose stimulus; IEA:EnsemblPlants.
DR GO; GO:0009736; P:cytokinin-activated signaling pathway; IEA:UniProtKB-KW.
DR GO; GO:0042742; P:defense response to bacterium; IEA:EnsemblPlants.
DR GO; GO:0010150; P:leaf senescence; IEA:EnsemblPlants.
DR GO; GO:0034757; P:negative regulation of iron ion transport; IEA:EnsemblPlants.
DR GO; GO:0010087; P:phloem or xylem histogenesis; IEA:EnsemblPlants.
DR GO; GO:0000160; P:phosphorelay signal transduction system; IEA:UniProtKB-KW.
DR GO; GO:0010271; P:regulation of chlorophyll catabolic process; IEA:EnsemblPlants.
DR GO; GO:0009909; P:regulation of flower development; IEA:EnsemblPlants.
DR GO; GO:0048509; P:regulation of meristem development; IEA:EnsemblPlants.
DR GO; GO:0010029; P:regulation of seed germination; IEA:EnsemblPlants.
DR GO; GO:0009651; P:response to salt stress; IEA:EnsemblPlants.
DR GO; GO:0009414; P:response to water deprivation; IEA:EnsemblPlants.
DR GO; GO:0080117; P:secondary growth; IEA:EnsemblPlants.
DR CDD; cd16922; HATPase_EvgS-ArcB-TorS-like; 1.
DR CDD; cd17546; REC_hyHK_CKI1_RcsC-like; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 6.10.250.1190; -; 1.
DR Gene3D; 3.30.450.350; CHASE domain; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR006189; CHASE_dom.
DR InterPro; IPR042240; CHASE_sf.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR PANTHER; PTHR43719:SF73; HISTIDINE KINASE 3; 1.
DR PANTHER; PTHR43719; TWO-COMPONENT HISTIDINE KINASE; 1.
DR Pfam; PF03924; CHASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00072; Response_reg; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM01079; CHASE; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00448; REC; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF52172; CheY-like; 2.
DR PROSITE; PS50839; CHASE; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 2.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Cytokinin signaling pathway {ECO:0000256|ARBA:ARBA00022864};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:OAY86071.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553, ECO:0000256|PROSITE-
KW ProRule:PRU00169}; Reference proteome {ECO:0000313|Proteomes:UP000092600};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT TRANSMEM 62..80
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 362..384
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 129..353
FT /note="CHASE"
FT /evidence="ECO:0000259|PROSITE:PS50839"
FT DOMAIN 418..635
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT DOMAIN 652..774
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT DOMAIN 800..937
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT COILED 391..421
FT /evidence="ECO:0000256|SAM:Coils"
FT MOD_RES 703
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
FT MOD_RES 850
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 943 AA; 106517 MW; CFF25C059B1FE910 CRC64;
MVFWWDFPKF PMTWFIDAEV MEEKARLLRN KRNLSFRCWR NHLYSHYFGS KKVRETWWRK
LLLLWVVGWV LCSLWIFMFM SSHANEKRRE TLANMCDERA RMLQDQFNVS MNHLQALAIL
VSTFHHSKHP SAVDQMTFAR YADRTAFERP LTSGVAYAVK VLRSEREQFE KQQGWTIKKM
YSSKQSPNRE NGRVHEIQEI SPPAEEYAPV IFAQDAYKHV VSLDMLTGKE DRENILRARE
SGKGVLTAPL QLVKSNRLGV ILTYAVYKSD LPSNATPTER IQAAIGYLGG IFDIESLVDK
LLHQLACNQS IIVDVYDTTN GKISMYGSNE TASGLYHKSM LNFGDPLRKH EMHCRFKQKP
PLPWLGITTS IGALVIALLI GYIFHATVNR IVKVEDDYRE MMELKKRAEA ADVAKSQAKI
ESGKLELEAV PFDLRAVLDD ILSLFCGKAQ EKELELAAFV SEQVPETLIG DPGRIRQIIT
NLIGNSIKFT EKGHIYLTVH LVEEVMIPLE VETEVQPMST VSGFPVADRR KSWERFKIFN
KEFSTSEKPF PATSPDQINL IISVEDTGAG IPFEAQSRVF TPFMQVGPSI SRIHGGTGIG
LSISKCLVNL MKGEIGFASK PQVGSTFTFT AVLSRAKTNS TEYKSFEFRG LTALVVDHRP
ARAKVTKYHL ERLGMHVDFS TNFSLVLPKI TSGNLGLKIV LVDKETWLKE SSQWPIFMNK
LRIGGQLDIP KLFILANSSS PIKSSLLSSN GFNYTIIMKP LRACMLQVSL RRALGGGDSE
NNRSGGLSSN SLHGLLHGRK ILVVDDNIVN IRVAAGALKK YGAEVTCADS GKKAIALLTP
PHDFDACFMD IQMPEMDGFE ATRRIREMET TLNDRIQHKE VSLEACGNKL HWHIPILAMT
ADVIQATHEE CLRCGMDGYV SKPFEGEQLY REVARFFNIT VKN
//
