ID   A0A199XNS0_9FLAO        Unreviewed;       945 AA.
AC   A0A199XNS0;
DT   05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2016, sequence version 1.
DT   24-JAN-2024, entry version 17.
DE   SubName: Full=Protease 3 {ECO:0000313|EMBL:OAZ02994.1};
DE            EC=3.4.24.55 {ECO:0000313|EMBL:OAZ02994.1};
GN   Name=ptrA_2 {ECO:0000313|EMBL:OAZ02994.1};
GN   ORFNames=FLB_26680 {ECO:0000313|EMBL:OAZ02994.1};
OS   Flavobacterium succinicans.
OC   Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC   Flavobacteriaceae; Flavobacterium.
OX   NCBI_TaxID=29536 {ECO:0000313|EMBL:OAZ02994.1, ECO:0000313|Proteomes:UP000093807};
RN   [1] {ECO:0000313|EMBL:OAZ02994.1, ECO:0000313|Proteomes:UP000093807}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DD5b {ECO:0000313|EMBL:OAZ02994.1,
RC   ECO:0000313|Proteomes:UP000093807};
RA   Poehlein A., Daniel R., Simeonova D.D.;
RT   "Draft genome sequence of Flavobacterium succinicans strain DD5b.";
RL   Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the peptidase M16 family.
CC       {ECO:0000256|ARBA:ARBA00007261, ECO:0000256|RuleBase:RU004447}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OAZ02994.1}.
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DR   EMBL; JMTM01000070; OAZ02994.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A199XNS0; -.
DR   PATRIC; fig|29536.5.peg.2764; -.
DR   OrthoDB; 9811314at2; -.
DR   Proteomes; UP000093807; Unassembled WGS sequence.
DR   GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR   GO; GO:0004222; F:metalloendopeptidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.830.10; Metalloenzyme, LuxS/M16 peptidase-like; 4.
DR   InterPro; IPR011249; Metalloenz_LuxS/M16.
DR   InterPro; IPR011765; Pept_M16_N.
DR   InterPro; IPR001431; Pept_M16_Zn_BS.
DR   InterPro; IPR007863; Peptidase_M16_C.
DR   PANTHER; PTHR43690; NARDILYSIN; 1.
DR   PANTHER; PTHR43690:SF34; ZINC PROTEASE PQQL-LIKE; 1.
DR   Pfam; PF00675; Peptidase_M16; 1.
DR   Pfam; PF05193; Peptidase_M16_C; 2.
DR   SUPFAM; SSF63411; LuxS/MPP-like metallohydrolase; 4.
DR   PROSITE; PS00143; INSULINASE; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:OAZ02994.1};
KW   Metalloprotease {ECO:0000256|ARBA:ARBA00023049};
KW   Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000313|EMBL:OAZ02994.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000093807};
KW   Signal {ECO:0000256|SAM:SignalP}; Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT   SIGNAL          1..28
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           29..945
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5008286724"
FT   DOMAIN          58..177
FT                   /note="Peptidase M16 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00675"
FT   DOMAIN          215..397
FT                   /note="Peptidase M16 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF05193"
FT   DOMAIN          705..874
FT                   /note="Peptidase M16 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF05193"
SQ   SEQUENCE   945 AA;  107714 MW;  7FF895FA6A481C24 CRC64;
     MLSTKHIFMK KFNQFALGIM LFPVAILAQT MDYGQAIPFD PNVKTGKLDN GLTYYIKKNA
     KPEKKVDLRL VVNAGSILED DDQQGLAHFM EHMCFNGTKR FPKNQLVDYL QSIGVKFGQH
     LNAYTSFDET VYFLPIPSDN PEKLEKGFQI LEDWAFNTVL TPEEIDKERG VVLEEYRLGL
     GAQKRMMGRY LPKMMYNSKY ANRLPIGQKE ILEKFKYETL TRFYKDWYRP NLMSVIVVGD
     IDVAEMEKKI KEHFSAYKNP ANEKVRNVFE VPNHKETFVA VESDKEASNT QVQLVYKDYD
     APKKITTIGD FRSYLVEGLF TTLLNNRLEE LTNSATPPFT FGYSYYGGTY ARTKKAYQSV
     AMMAEDKQLS ALKVLVTENE RARKFGFTSG ELDRAKADFL AQIEKNYNDR TKTDSENFVE
     EMQLNFLEQE PLPGIEWTFE TMKKILPTIA LADVNGFIKN YIKEDNRVVV FTGPQKDNLK
     KVTEQEVLET LKVNEADLKP YEDKAVATSL LRKEAKAGTI VKREANATLG TKTLVLSNGV
     KVVYKTTDFK NDEVLFEAVS LGGSNLYSNE VMKKVQFANG ALAEAGFSGL KLNDINKFMT
     GKIARVNPYI GQTTEGLRGN TTPKDLEYLF QMVHAYFTDL NFDPEAFEGF KQKQASFFKN
     MASQPQYYFQ QEFYTYLNKE NPRFNGIMPT DKSWAETDYK LAYDKYKERF ANAADFEFFF
     VGNVDDKTIE AFATKYLASL PTTAAKEKTV DLGYRMLKGD LKKVVNKGTD PKSNVNIMFY
     GEAKYSPKEA LAIEALGEVL TIKLIEQLRE SESGVYGVSA RGSMNKVPYG SYNFTINFPC
     GPDNAEKLTA SALNELQKII TNGPEEKDVA KYKEGELADY RKDSKENRFW LTNFTRSFLY
     GSNPENALKY EAEVNAITAK DIQEVAKKYL TKDKVIGMLM PESKS
//