ID A0A1A0H619_9ASCO Unreviewed; 328 AA.
AC A0A1A0H619;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=Golgi apparatus membrane protein TVP38 {ECO:0000256|ARBA:ARBA00013533};
DE AltName: Full=Golgi apparatus membrane protein tvp38 {ECO:0000256|ARBA:ARBA00020673};
GN ORFNames=METBIDRAFT_45716 {ECO:0000313|EMBL:OBA19476.1};
OS Metschnikowia bicuspidata var. bicuspidata NRRL YB-4993.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Metschnikowiaceae; Metschnikowia.
OX NCBI_TaxID=869754 {ECO:0000313|EMBL:OBA19476.1, ECO:0000313|Proteomes:UP000092555};
RN [1] {ECO:0000313|EMBL:OBA19476.1, ECO:0000313|Proteomes:UP000092555}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL YB-4993 {ECO:0000313|EMBL:OBA19476.1,
RC ECO:0000313|Proteomes:UP000092555};
RG DOE Joint Genome Institute;
RA Riley R., Haridas S., Wolfe K.H., Lopes M.R., Hittinger C.T., Goker M.,
RA Salamov A., Wisecaver J., Long T.M., Aerts A.L., Barry K., Choi C.,
RA Clum A., Coughlan A.Y., Deshpande S., Douglass A.P., Hanson S.J.,
RA Klenk H.-P., LaButti K., Lapidus A., Lindquist E., Lipzen A.,
RA Meier-kolthoff J.P., Ohm R.A., Otillar R.P., Pangilinan J., Peng Y.,
RA Rokas A., Rosa C.A., Scheuner C., Sibirny A.A., Slot J.C., Stielow J.B.,
RA Sun H., Kurtzman C.P., Blackwell M., Grigoriev I.V., Jeffries T.W.;
RT "Comparative genomics of biotechnologically important yeasts.";
RL Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Golgi membrane protein involved in vesicular trafficking and
CC spindle migration. {ECO:0000256|ARBA:ARBA00002978}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the TVP38/TMEM64 family.
CC {ECO:0000256|ARBA:ARBA00008640}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OBA19476.1}.
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DR EMBL; LXTC01000006; OBA19476.1; -; Genomic_DNA.
DR RefSeq; XP_018710004.1; XM_018857952.1.
DR AlphaFoldDB; A0A1A0H619; -.
DR STRING; 869754.A0A1A0H619; -.
DR GeneID; 30030928; -.
DR OrthoDB; 2385736at2759; -.
DR Proteomes; UP000092555; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR032816; VTT_dom.
DR PANTHER; PTHR47549:SF1; GOLGI APPARATUS MEMBRANE PROTEIN TVP38; 1.
DR PANTHER; PTHR47549; GOLGI APPARATUS MEMBRANE PROTEIN TVP38-RELATED; 1.
DR Pfam; PF09335; SNARE_assoc; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000092555};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 29..48
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 68..101
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 107..126
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 223..241
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 89..204
FT /note="VTT"
FT /evidence="ECO:0000259|Pfam:PF09335"
FT REGION 297..328
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 314..328
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 328 AA; 36089 MW; DA7B1B1DF96B7829 CRC64;
MLQTQVQILN DLGRTSSEWF QSQLTKKKAL CIVGGLLGFV AGVTLLVFHK RFIAAMADVS
DLIRASKFGG LALFVAIFFV GFPPLLGFSA LSMLCGMVYG FPGGWPLLAA ASTIGSFASF
MVYRYFLRNQ AERLVARNEK FRAFAEILKE DASLFLLILL RLCPLPYSLS NGALAAIPNL
PASTYLLASV ITSPKMFMHV FIGHTIKNLG DAERPAAAKA LDVFSILLTG CAVSLASYII
YRRMQQKLES YHERGPNNDA MYEDLVFGDF GESPELGTNL ELDAAEFDDD HFIIADDDED
LPAGTNARGL DLLDEPQELG KPPKYRDY
//
