ID A0A1A0HI86_9ASCO Unreviewed; 462 AA.
AC A0A1A0HI86;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 08-NOV-2023, entry version 25.
DE RecName: Full=Citrate synthase {ECO:0000256|RuleBase:RU000441};
GN ORFNames=METBIDRAFT_30031 {ECO:0000313|EMBL:OBA23597.1};
OS Metschnikowia bicuspidata var. bicuspidata NRRL YB-4993.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Metschnikowiaceae; Metschnikowia.
OX NCBI_TaxID=869754 {ECO:0000313|EMBL:OBA23597.1, ECO:0000313|Proteomes:UP000092555};
RN [1] {ECO:0000313|EMBL:OBA23597.1, ECO:0000313|Proteomes:UP000092555}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL YB-4993 {ECO:0000313|EMBL:OBA23597.1,
RC ECO:0000313|Proteomes:UP000092555};
RG DOE Joint Genome Institute;
RA Riley R., Haridas S., Wolfe K.H., Lopes M.R., Hittinger C.T., Goker M.,
RA Salamov A., Wisecaver J., Long T.M., Aerts A.L., Barry K., Choi C.,
RA Clum A., Coughlan A.Y., Deshpande S., Douglass A.P., Hanson S.J.,
RA Klenk H.-P., LaButti K., Lapidus A., Lindquist E., Lipzen A.,
RA Meier-kolthoff J.P., Ohm R.A., Otillar R.P., Pangilinan J., Peng Y.,
RA Rokas A., Rosa C.A., Scheuner C., Sibirny A.A., Slot J.C., Stielow J.B.,
RA Sun H., Kurtzman C.P., Blackwell M., Grigoriev I.V., Jeffries T.W.;
RT "Comparative genomics of biotechnologically important yeasts.";
RL Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the citrate synthase family.
CC {ECO:0000256|ARBA:ARBA00010566, ECO:0000256|RuleBase:RU000441}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OBA23597.1}.
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DR EMBL; LXTC01000001; OBA23597.1; -; Genomic_DNA.
DR RefSeq; XP_018714078.1; XM_018855536.1.
DR AlphaFoldDB; A0A1A0HI86; -.
DR STRING; 869754.A0A1A0HI86; -.
DR GeneID; 30028512; -.
DR OrthoDB; 3513214at2759; -.
DR Proteomes; UP000092555; Unassembled WGS sequence.
DR GO; GO:0004108; F:citrate (Si)-synthase activity; IEA:InterPro.
DR GO; GO:0006101; P:citrate metabolic process; IEA:InterPro.
DR GO; GO:0006099; P:tricarboxylic acid cycle; IEA:InterPro.
DR Gene3D; 1.10.580.10; Citrate Synthase, domain 1; 1.
DR Gene3D; 1.10.230.10; Cytochrome P450-Terp, domain 2; 1.
DR InterPro; IPR016142; Citrate_synth-like_lrg_a-sub.
DR InterPro; IPR016143; Citrate_synth-like_sm_a-sub.
DR InterPro; IPR002020; Citrate_synthase.
DR InterPro; IPR019810; Citrate_synthase_AS.
DR InterPro; IPR010109; Citrate_synthase_euk.
DR InterPro; IPR036969; Citrate_synthase_sf.
DR NCBIfam; TIGR01793; cit_synth_euk; 1.
DR PANTHER; PTHR11739; CITRATE SYNTHASE; 1.
DR PANTHER; PTHR11739:SF8; CITRATE SYNTHASE, MITOCHONDRIAL; 1.
DR Pfam; PF00285; Citrate_synt; 1.
DR PRINTS; PR00143; CITRTSNTHASE.
DR SUPFAM; SSF48256; Citrate synthase; 1.
DR PROSITE; PS00480; CITRATE_SYNTHASE; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000092555};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU000441}.
FT ACT_SITE 296
FT /evidence="ECO:0000256|PIRSR:PIRSR610109-1"
FT ACT_SITE 342
FT /evidence="ECO:0000256|PIRSR:PIRSR610109-1"
FT ACT_SITE 397
FT /evidence="ECO:0000256|PIRSR:PIRSR610109-1"
SQ SEQUENCE 462 AA; 51221 MW; E0EEB38009A04098 CRC64;
MSAVRSFQRS ALRRSLGIRT YATEPILKAR LAEILPEKAE EVKQLKKEHG KTVIGEVLLE
QAYGGMRGIK GLVWEGSVLD PIEGIRFRGR TIPDIQKELP KAPGGSEPLP EALFWLLLTG
ETPSVAQTKA LSEEFAARSA LPKHVEELID RSPSHLHPMA QFSIAVTALE SESQFAKAYA
KGAPKADYWK YTYEDSIDLL AKLPNIAARI YRNVFHDGKL AGEISKDLDY GANLATLLGF
GENKEFVELM RLYLTIHSDH EGGNVSAHTT HLVGSALSSP FLSLAAGLNG LAGPLHGRAN
QEVLEWLFKL RNDLNGDHSK EAIEKYLWDT LNSGRVVPGY GHAVLRKTDP RYTAQREFAL
KHMPNDELFK LVSNIYEVAP GVLTKHGKTK NPWPNVDSHS GVLLQYYGLT EESFYTVLFG
VSRAFGVLPQ LILDRGLGLP IERPKSFSTE KYIELVKSIG KN
//
