ID A0A1A0TBW2_9MYCO Unreviewed; 274 AA.
AC A0A1A0TBW2;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=3-alpha-hydroxysteroid dehydrogenase {ECO:0000313|EMBL:OBB55879.1};
GN ORFNames=A5757_02180 {ECO:0000313|EMBL:OBB55879.1};
OS Mycobacterium sp. 852013-51886_SCH5428379.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycobacterium.
OX NCBI_TaxID=1834111 {ECO:0000313|EMBL:OBB55879.1, ECO:0000313|Proteomes:UP000091910};
RN [1] {ECO:0000313|Proteomes:UP000091910}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=852013-51886_SCH5428379 {ECO:0000313|Proteomes:UP000091910};
RA Sutton G., Brinkac L., Sanka R., Adams M., Lau E., Mehaffy C., Tameris M.,
RA Hatherill M., Hanekom W., Mahomed H., Mcshane H.;
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the short-chain dehydrogenases/reductases (SDR)
CC family. {ECO:0000256|ARBA:ARBA00006484}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OBB55879.1}.
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DR EMBL; LZSU01000051; OBB55879.1; -; Genomic_DNA.
DR RefSeq; WP_066837761.1; NZ_LZSU01000051.1.
DR AlphaFoldDB; A0A1A0TBW2; -.
DR STRING; 1834111.A5757_02180; -.
DR OrthoDB; 5786478at2; -.
DR Proteomes; UP000091910; Unassembled WGS sequence.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR001509; Epimerase_deHydtase.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR002347; SDR_fam.
DR PANTHER; PTHR42760:SF135; 2,3-DIHYDRO-2,3-DIHYDROXYBENZOATE DEHYDROGENASE; 1.
DR PANTHER; PTHR42760; SHORT-CHAIN DEHYDROGENASES/REDUCTASES FAMILY MEMBER; 1.
DR Pfam; PF13561; adh_short_C2; 1.
DR Pfam; PF01370; Epimerase; 1.
DR PRINTS; PR00081; GDHRDH.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000091910}.
FT DOMAIN 15..135
FT /note="NAD-dependent epimerase/dehydratase"
FT /evidence="ECO:0000259|Pfam:PF01370"
SQ SEQUENCE 274 AA; 28640 MW; 648E84B4463F4ACC CRC64;
MGGIEQLWRY DGKRVVVTGC ASGIGAHLVR QLGELGAQVV GLDMRRPAVD LDEFVEMDLS
DQASIDHAVA AIGGDVDVVF NVAGVSSGIG DPPLVVRINF LGARHFTEAM LPRLRTGSAV
VSVSSLAAAA YLDNAQTTGE LVRTPTMEDG IAWCGDHPEA LADGGYRLAK EALILYTMRS
AGPLGARGIR INCTGPGVTE TPILDQLRTA YGSAFLDDIP KPLGRVSEPE EQAAVLLFLG
SDAASYITGQ VIWVDGGNLA GRVAATLDAT SEGH
//
