ID A0A1A1WMV0_9MYCO Unreviewed; 341 AA.
AC A0A1A1WMV0;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=TetR family transcriptional regulator {ECO:0000313|EMBL:OBF08240.1};
GN ORFNames=A5730_11110 {ECO:0000313|EMBL:OBF08240.1};
OS Mycobacterium sp. ACS4054.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycobacterium.
OX NCBI_TaxID=1834119 {ECO:0000313|EMBL:OBF08240.1, ECO:0000313|Proteomes:UP000091876};
RN [1] {ECO:0000313|EMBL:OBF08240.1, ECO:0000313|Proteomes:UP000091876}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ACS4054 {ECO:0000313|EMBL:OBF08240.1,
RC ECO:0000313|Proteomes:UP000091876};
RA Kjaerup R.B., Dalgaard T.S., Juul-Madsen H.R.;
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OBF08240.1}.
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DR EMBL; LZHV01000041; OBF08240.1; -; Genomic_DNA.
DR RefSeq; WP_067899171.1; NZ_LZHV01000041.1.
DR AlphaFoldDB; A0A1A1WMV0; -.
DR STRING; 1834119.A5730_11110; -.
DR OrthoDB; 4530117at2; -.
DR Proteomes; UP000091876; Unassembled WGS sequence.
DR GO; GO:0016289; F:CoA hydrolase activity; IEA:UniProt.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:UniProt.
DR CDD; cd03443; PaaI_thioesterase; 1.
DR Gene3D; 3.10.129.10; Hotdog Thioesterase; 1.
DR Gene3D; 1.10.357.10; Tetracycline Repressor, domain 2; 1.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR029069; HotDog_dom_sf.
DR InterPro; IPR001647; HTH_TetR.
DR InterPro; IPR003736; PAAI_dom.
DR InterPro; IPR036271; Tet_transcr_reg_TetR-rel_C_sf.
DR InterPro; IPR006683; Thioestr_dom.
DR NCBIfam; TIGR00369; unchar_dom_1; 1.
DR PANTHER; PTHR47506:SF1; HTH-TYPE TRANSCRIPTIONAL REGULATOR YJDC; 1.
DR PANTHER; PTHR47506; TRANSCRIPTIONAL REGULATORY PROTEIN; 1.
DR Pfam; PF03061; 4HBT; 1.
DR Pfam; PF00440; TetR_N; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR SUPFAM; SSF48498; Tetracyclin repressor-like, C-terminal domain; 1.
DR SUPFAM; SSF54637; Thioesterase/thiol ester dehydrase-isomerase; 1.
DR PROSITE; PS50977; HTH_TETR_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00335}; Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 10..70
FT /note="HTH tetR-type"
FT /evidence="ECO:0000259|PROSITE:PS50977"
FT DNA_BIND 33..52
FT /note="H-T-H motif"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00335"
SQ SEQUENCE 341 AA; 37110 MW; CAD931E59E0F0C8A CRC64;
MADLGDYVEV TRGDRFIRTA VEILGETGRT DFTVQEVVAR SKTSLRAFYQ HFSSKDELLL
ALFDRTIAHS VQTWRAETEG LASTAALKLV IDRISQQPES STQDSLNRAL TLYNQHLAET
RPRDYARVLS PLHRLIRDIV GQGITEGVFN PGLDVAAAAA IVMQTVMGAQ RLHWLGAELN
GAPVDVGHLY EFCSRALGIR DAEESSPPSL SELFAQIGMR PGTREGEFAM TMPVSPAVVN
TSGALQGGLV ATLVDVAAGQ FGLDYLAPGT TMTTADLFVR YLRPIRQGSA FAVPRMLRSG
RRAMVMQVDI YGDDDELLAT ATVNFAVING KTPELPNWPG T
//
