ID A0A1A1YAC1_9MYCO Unreviewed; 467 AA.
AC A0A1A1YAC1;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=MFS transporter {ECO:0000313|EMBL:OBF28261.1};
GN ORFNames=A5724_27975 {ECO:0000313|EMBL:OBF28261.1};
OS Mycobacterium sp. ACS1612.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycobacterium.
OX NCBI_TaxID=1834117 {ECO:0000313|EMBL:OBF28261.1, ECO:0000313|Proteomes:UP000092025};
RN [1] {ECO:0000313|Proteomes:UP000092025}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ACS1612 {ECO:0000313|Proteomes:UP000092025};
RA Sutton G., Brinkac L., Sanka R., Adams M., Lau E., Kiyimba A., Mayanja H.,
RA Musoke P., Ssengooba W., Joloba M.;
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC
CC 2.A.40) family. Azg-like subfamily. {ECO:0000256|ARBA:ARBA00005697}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OBF28261.1}.
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DR EMBL; LZHZ01000063; OBF28261.1; -; Genomic_DNA.
DR RefSeq; WP_067809088.1; NZ_LZHZ01000063.1.
DR AlphaFoldDB; A0A1A1YAC1; -.
DR STRING; 1834117.A5724_27975; -.
DR OrthoDB; 9808458at2; -.
DR Proteomes; UP000092025; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015205; F:nucleobase transmembrane transporter activity; IEA:InterPro.
DR GO; GO:1904823; P:purine nucleobase transmembrane transport; IEA:UniProt.
DR InterPro; IPR045018; Azg-like.
DR InterPro; IPR006043; NCS2.
DR PANTHER; PTHR43337; XANTHINE/URACIL PERMEASE C887.17-RELATED; 1.
DR PANTHER; PTHR43337:SF1; XANTHINE_URACIL PERMEASE C887.17-RELATED; 1.
DR Pfam; PF00860; Xan_ur_permease; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000092025};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 21..39
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 51..71
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 78..97
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 103..122
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 134..157
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 177..197
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 204..222
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 265..283
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 348..367
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 413..431
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 443..461
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 467 AA; 48051 MW; E7617D7B8356B396 CRC64;
MDRFFEISER QSTVAAELRG GVVTFIAMAY IIVLNPIILS SAPDVTGQKL QFAEVSAMTS
LAAGVMTILF GVIARLPFAF AAGLGINSFL ATTVVGSVTW AEAMGLVVID GLIIVLLAAT
GLRRLVFDAV PLQLKLAITA GIGLFILFIG LVDAGFIGAT GQPSPPVGLG HGGVGSINTV
PAVVFVFTLL VTAILVVRRV RGGILIGLVI GTLLAVAIEA IWHLGSATEH PGGWSLSVPT
LSGSPFALPD LSLAGDFSFG SFGRIGVLAA VMLVFTLVFA NFFDAMGTFT GLAREANLAD
AQGTFPRLRS ALIVEGAGAV VGGATSSSSN TVFIESGAGI EEGARTGLAS LVTGVLFLAA
MFVSPLASIV PTEVAAAALV IVGVMMMSQL RHIDISEFSV AVPVVLTVAV MPFSYSIANG
IGVGFIAWVV LRSAAGKARE ISPLLWVVAA GFVLYFARGW IETLIGL
//
