ID A0A1A1YG44_9MYCO Unreviewed; 554 AA.
AC A0A1A1YG44;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE SubName: Full=GMC oxidoreductase {ECO:0000313|EMBL:OBF30289.1};
GN ORFNames=A5724_24030 {ECO:0000313|EMBL:OBF30289.1};
OS Mycobacterium sp. ACS1612.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycobacterium.
OX NCBI_TaxID=1834117 {ECO:0000313|EMBL:OBF30289.1, ECO:0000313|Proteomes:UP000092025};
RN [1] {ECO:0000313|Proteomes:UP000092025}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ACS1612 {ECO:0000313|Proteomes:UP000092025};
RA Sutton G., Brinkac L., Sanka R., Adams M., Lau E., Kiyimba A., Mayanja H.,
RA Musoke P., Ssengooba W., Joloba M.;
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974,
CC ECO:0000256|PIRSR:PIRSR000137-2};
CC -!- SIMILARITY: Belongs to the GMC oxidoreductase family.
CC {ECO:0000256|ARBA:ARBA00010790, ECO:0000256|RuleBase:RU003968}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OBF30289.1}.
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DR EMBL; LZHZ01000054; OBF30289.1; -; Genomic_DNA.
DR RefSeq; WP_067806886.1; NZ_LZHZ01000054.1.
DR AlphaFoldDB; A0A1A1YG44; -.
DR STRING; 1834117.A5724_24030; -.
DR OrthoDB; 9785276at2; -.
DR Proteomes; UP000092025; Unassembled WGS sequence.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR GO; GO:0016614; F:oxidoreductase activity, acting on CH-OH group of donors; IEA:InterPro.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR Gene3D; 3.30.560.10; Glucose Oxidase, domain 3; 1.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR012132; GMC_OxRdtase.
DR InterPro; IPR000172; GMC_OxRdtase_N.
DR InterPro; IPR007867; GMC_OxRtase_C.
DR PANTHER; PTHR11552:SF147; CHOLINE DEHYDROGENASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR11552; GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE; 1.
DR Pfam; PF05199; GMC_oxred_C; 1.
DR Pfam; PF00732; GMC_oxred_N; 1.
DR PIRSF; PIRSF000137; Alcohol_oxidase; 1.
DR SUPFAM; SSF54373; FAD-linked reductases, C-terminal domain; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR PROSITE; PS00623; GMC_OXRED_1; 1.
DR PROSITE; PS00624; GMC_OXRED_2; 1.
PE 3: Inferred from homology;
KW FAD {ECO:0000256|ARBA:ARBA00022827, ECO:0000256|PIRSR:PIRSR000137-2};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630,
KW ECO:0000256|RuleBase:RU003968};
KW Reference proteome {ECO:0000313|Proteomes:UP000092025}.
FT DOMAIN 93..116
FT /note="Glucose-methanol-choline oxidoreductase N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS00623"
FT DOMAIN 265..279
FT /note="Glucose-methanol-choline oxidoreductase N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS00624"
FT BINDING 103..106
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR000137-2"
SQ SEQUENCE 554 AA; 60197 MW; 0DA672BEEDBAB86B CRC64;
MPAFDYVILG AGAAGCVLAN RLSEDPRTEV LLVEAGPPAR GPYFAIPMMG AGLFEQRTDH
PDPHAYEGYK HSFVYQLQPY GAADKLNERW VRGKAVGGST AINGLVYNRG NREDYDELER
LGNHGWGWDN ILPVFKAFED NQFGPSPTRG VGGPLHISQP RFPDELSQYI IDAAANTGLH
SVEDYNESDD ERVGPAMAMI RRGLRVSAAK AFLDPVLKRP NLHLATDTYA QRLIFENGRA
VGAEIRTGGN TSEVRARREV IVAMGALHTP KILQLSGVGP RDVLEKAGVP VYLERDNVGR
RMTEHFCAIV TYRLKDDLGY NRQLRTTVGK ALAALKFAAT RRGPLATPTG DVMAIFKTRP
ELDRVDGQFL ARLMSVADVS GGERGQIDSH GGVSCAAEIL RPTSEGRVWI TSPDPGAALS
IEPNYLATDY DRTTMVGVVR KIRQIFEQSP LAEHVEKETT PGKGVQTDEE IIDATIKTGA
TGSHAAGTCM MGPTDDEIVD DQLRVRGIDG LRIVDCSIMP KQMSGNLAGP MLAMAGRAAE
LILDTAPAEK ARRA
//
