ID A0A1A1YP06_9MYCO Unreviewed; 544 AA.
AC A0A1A1YP06;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE SubName: Full=Long-chain fatty acid--CoA ligase {ECO:0000313|EMBL:OBF33013.1};
GN ORFNames=A5724_20540 {ECO:0000313|EMBL:OBF33013.1};
OS Mycobacterium sp. ACS1612.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycobacterium.
OX NCBI_TaxID=1834117 {ECO:0000313|EMBL:OBF33013.1, ECO:0000313|Proteomes:UP000092025};
RN [1] {ECO:0000313|Proteomes:UP000092025}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ACS1612 {ECO:0000313|Proteomes:UP000092025};
RA Sutton G., Brinkac L., Sanka R., Adams M., Lau E., Kiyimba A., Mayanja H.,
RA Musoke P., Ssengooba W., Joloba M.;
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OBF33013.1}.
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DR EMBL; LZHZ01000037; OBF33013.1; -; Genomic_DNA.
DR RefSeq; WP_067804477.1; NZ_LZHZ01000037.1.
DR AlphaFoldDB; A0A1A1YP06; -.
DR STRING; 1834117.A5724_20540; -.
DR OrthoDB; 3671040at2; -.
DR Proteomes; UP000092025; Unassembled WGS sequence.
DR GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR028154; AMP-dep_Lig_C.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR PANTHER; PTHR22754:SF32; DISCO-INTERACTING PROTEIN 2; 1.
DR PANTHER; PTHR22754; DISCO-INTERACTING PROTEIN 2 DIP2 -RELATED; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF14535; AMP-binding_C_2; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 4: Predicted;
KW Ligase {ECO:0000313|EMBL:OBF33013.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000092025}.
FT DOMAIN 28..400
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 444..536
FT /note="AMP-dependent ligase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF14535"
FT REGION 1..23
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..18
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 544 AA; 58318 MW; 42AA924051F838F6 CRC64;
MSRFTETMYR NAQRSSKGMV TGEPHIPVRH SWAEVHDQAR CVAGGLAAAG IGPGDAVAVL
AGAPVEIAPT AQGIWMRGAS VTMLHQPTPR TDLVRWAKET ADVINMITAK AVVISDPFMA
AAPVLYGLGM TVLTAESLLA SAPITPVDTD DDDVALMQLT SGSTGSPKAV QITHANVVAN
AEAMMAGCDF DPDRDVIVSW LPCFHDMGMT GYLTVPMYVG AELVKITPMD FLRDTLLWAR
LIDKYKGTMT AAPNFAYNMF ANRLRKQATV GDFDLSSLRW ALSGAEQVDP VDVEDLCIAG
APFGLKPEAI IPAYGMAETT VAVSFSECGG GMVVDEVDAN LLAVLHRAIP VTGGHTRRLV
TLGRPLQGLE VRVVDEYGAE LPARGVGVIE VRGEPVTRGY TTMGGFISAQ NERGWYDTGD
LGYLTETGSV VVCGRLKDVI IMAGRNIFPT DIERAAGRVK GVRPGCAVAV RLDAGMSRET
FAVAVECQEF ADKQQVRRVE RQVAHEVFAE VDVRPRNVVV LEPGMIPKTP SGKLRRAHAL
SLVT
//
