ID A0A1A2KQ08_9MYCO Unreviewed; 383 AA.
AC A0A1A2KQ08;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 24-JAN-2024, entry version 27.
DE SubName: Full=Uroporphyrinogen-III synthase {ECO:0000313|EMBL:OBG80618.1};
GN ORFNames=A5699_10240 {ECO:0000313|EMBL:OBG80618.1};
OS Mycobacterium sp. E802.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycobacterium.
OX NCBI_TaxID=1834152 {ECO:0000313|EMBL:OBG80618.1, ECO:0000313|Proteomes:UP000092062};
RN [1] {ECO:0000313|EMBL:OBG80618.1, ECO:0000313|Proteomes:UP000092062}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=E802 {ECO:0000313|EMBL:OBG80618.1,
RC ECO:0000313|Proteomes:UP000092062};
RA Kjaerup R.B., Dalgaard T.S., Juul-Madsen H.R.;
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OBG80618.1}.
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DR EMBL; LZJD01000177; OBG80618.1; -; Genomic_DNA.
DR RefSeq; WP_067775768.1; NZ_LZJD01000177.1.
DR AlphaFoldDB; A0A1A2KQ08; -.
DR Proteomes; UP000092062; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004852; F:uroporphyrinogen-III synthase activity; IEA:InterPro.
DR GO; GO:0000160; P:phosphorelay signal transduction system; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR GO; GO:0006780; P:uroporphyrinogen III biosynthetic process; IEA:InterPro.
DR CDD; cd06578; HemD; 1.
DR CDD; cd00383; trans_reg_C; 1.
DR Gene3D; 3.40.50.10090; -; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR036108; 4pyrrol_syn_uPrphyn_synt_sf.
DR InterPro; IPR003754; 4pyrrol_synth_uPrphyn_synth.
DR InterPro; IPR001867; OmpR/PhoB-type_DNA-bd.
DR InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor.
DR InterPro; IPR039793; UROS/Hem4.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR40082; BLR5956 PROTEIN; 1.
DR PANTHER; PTHR40082:SF1; BLR5956 PROTEIN; 1.
DR Pfam; PF02602; HEM4; 1.
DR Pfam; PF00486; Trans_reg_C; 1.
DR SMART; SM00862; Trans_reg_C; 1.
DR SUPFAM; SSF46894; C-terminal effector domain of the bipartite response regulators; 1.
DR SUPFAM; SSF69618; HemD-like; 1.
DR PROSITE; PS51755; OMPR_PHOB; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|PROSITE-ProRule:PRU01091}.
FT DOMAIN 281..374
FT /note="OmpR/PhoB-type"
FT /evidence="ECO:0000259|PROSITE:PS51755"
FT DNA_BIND 281..374
FT /note="OmpR/PhoB-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01091"
SQ SEQUENCE 383 AA; 40929 MW; 2503452AC33EF27F CRC64;
MSDPDWAPLT GFRVAVTSAR RADELSALLR RRGATVTSAA AITMVPLPDD DELRAHTAAL
IEVPPDIVVA TTGIGFRGWM AAADGWGLDG NLADALATAR IVSRGPKATG ALRAAGLPEE
WSPESESSRE VLRYLIEQGV AGQRVAVQLH GATDEWDPFP EFLDELRAAG AEVVPIRVYR
WHPAPRDGEF DQMVTGIAEK RYDAVSFTSA MAVASVLMRA TEMGLADRVV AALRTDVHAM
CVGPVTARPL VRLGIPSSAP ERMRLGALAR HITDELPLLQ ARTVRVAGHT LEIRGTCVVV
DGVVKSLSPA AMATIRALAH RPGAVVSRFD LLSALPGTGT DTHAVETAVL RLRTALGDKN
IVSTVVKRGY RLAVDEPEMA RAR
//
