ID A0A1A2L3N6_9MYCO Unreviewed; 341 AA.
AC A0A1A2L3N6;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=2-dehydropantoate 2-reductase {ECO:0000313|EMBL:OBG84770.1};
GN ORFNames=A5699_25905 {ECO:0000313|EMBL:OBG84770.1};
OS Mycobacterium sp. E802.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycobacterium.
OX NCBI_TaxID=1834152 {ECO:0000313|EMBL:OBG84770.1, ECO:0000313|Proteomes:UP000092062};
RN [1] {ECO:0000313|EMBL:OBG84770.1, ECO:0000313|Proteomes:UP000092062}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=E802 {ECO:0000313|EMBL:OBG84770.1,
RC ECO:0000313|Proteomes:UP000092062};
RA Kjaerup R.B., Dalgaard T.S., Juul-Madsen H.R.;
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the ketopantoate reductase family.
CC {ECO:0000256|ARBA:ARBA00007870}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OBG84770.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; LZJD01000094; OBG84770.1; -; Genomic_DNA.
DR RefSeq; WP_067770380.1; NZ_LZJD01000094.1.
DR AlphaFoldDB; A0A1A2L3N6; -.
DR Proteomes; UP000092062; Unassembled WGS sequence.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR013328; 6PGD_dom2.
DR InterPro; IPR013752; KPA_reductase.
DR InterPro; IPR013332; KPR_N.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR43765; 2-DEHYDROPANTOATE 2-REDUCTASE-RELATED; 1.
DR PANTHER; PTHR43765:SF2; 2-DEHYDROPANTOATE 2-REDUCTASE-RELATED; 1.
DR Pfam; PF02558; ApbA; 1.
DR Pfam; PF08546; ApbA_C; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
FT DOMAIN 10..146
FT /note="Ketopantoate reductase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02558"
FT DOMAIN 187..301
FT /note="Ketopantoate reductase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF08546"
SQ SEQUENCE 341 AA; 36363 MW; 09678DD42B7B24D8 CRC64;
MARTLTRPFV VYGVGAIGGV IAGQLRLAGY DVTAVARGAH LNAIRTCGLT LVTQAGTDVV
DLPAAADAGE VDWSTRPVVI LAVKSHQTAA ALDDLSAHAP ADTPVFVAQN GVANEAAALR
RFANVYGVTV MLPAAHLDPG VVIQQSHPVA GILDLGRYPT GRDALAEQIC SALRVARFES
QVRDDVMAWK YRKLIANLGN GVIAAYRPGP QADTLIARAR EEAERVLTAA GISFVTAEQD
AQRRGDLLQG RVHDDYFSST WQSVARGHTQ VETDWFNGEI VLQARLHGQS APVNELIQRV
TAEHARVGRP VRSLDAAAAL KKLGPEPDAQ FRHDIVVTTS A
//
