ID A0A1A2NC94_9MYCO Unreviewed; 699 AA.
AC A0A1A2NC94;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=SSD domain-containing protein {ECO:0000259|PROSITE:PS50156};
GN ORFNames=A5695_15780 {ECO:0000313|EMBL:OBH12650.1};
OS Mycobacterium sp. E1747.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycobacterium.
OX NCBI_TaxID=1834128 {ECO:0000313|EMBL:OBH12650.1, ECO:0000313|Proteomes:UP000092218};
RN [1] {ECO:0000313|Proteomes:UP000092218}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=E1747 {ECO:0000313|Proteomes:UP000092218};
RA Sutton G., Brinkac L., Sanka R., Adams M., Lau E., Sam S., Sreng N.,
RA Him V., Kerleguer A., Cheng S.;
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the resistance-nodulation-cell division (RND)
CC (TC 2.A.6) family. MmpL subfamily. {ECO:0000256|ARBA:ARBA00010157}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OBH12650.1}.
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DR EMBL; LZJI01000047; OBH12650.1; -; Genomic_DNA.
DR RefSeq; WP_068078608.1; NZ_LZJI01000047.1.
DR AlphaFoldDB; A0A1A2NC94; -.
DR STRING; 1834128.A5695_15780; -.
DR OrthoDB; 2365435at2; -.
DR Proteomes; UP000092218; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR004869; MMPL_dom.
DR InterPro; IPR000731; SSD.
DR PANTHER; PTHR33406; MEMBRANE PROTEIN MJ1562-RELATED; 1.
DR PANTHER; PTHR33406:SF6; MEMBRANE PROTEIN SCO0839-RELATED; 1.
DR Pfam; PF03176; MMPL; 2.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR PROSITE; PS50156; SSD; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 178..196
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 203..226
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 238..258
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 279..302
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 308..333
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 369..388
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 513..530
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 539..561
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 573..594
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 606..639
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 216..333
FT /note="SSD"
FT /evidence="ECO:0000259|PROSITE:PS50156"
SQ SEQUENCE 699 AA; 71216 MW; 6C7BE8D0A704DD11 CRC64;
MVWDRLAAAV TGRCSWLIAL AAVLLGGVFL ALIGANGAAG QAPLSVPTRS DSAKVDAMFR
HFPGGDRVPL ILVVSRTDGA ALGPADVAAA QAARDRMQAA ATPGGATGAA PPQVSADGKA
AISVVPIGAD LSGLDLSDAV ATLRRAASTG LPAQLAAHVT GGPAFGADIA GAFTNANVTL
LAVTASVVAL LLVATYRSPV LWLVPLLVVG FADRVAAAVG TAVASLTGLS FDGATSGITS
VLVFGAGTNY ALLLISRYRQ ELRRHPEHRD ALRRAVRMAG PAIVASNATV VLALLALLFA
STPSTRSLGA LAACGLVVAA VSALVILPPL LALCGRRLFW PFVPRPEDTA TADSGAWQRI
GEWVNRRPAL VATAAIAGLA VLATGLLGTR IGLSQTDQFR VHADSVSGYD IVAAHFPAGL
VNPTLVIAPT VSQMPQAISA TRGVVSATES GRSSSGLSKW SVVIDAPPSS ERAFNIIAAL
RQTTKSASPS ALVGGADAQA LDVRDAATRD RHLLIPAILA VILLVLYVLL RSALAPPTLL
AATILGALAA IGVGGWTSSH VFGFPALDNS TPLFAFLFLA ALGVDYTIFL VTRAREESAE
RGARAGMVAA VSATGGVITS AGIVLAAVFC VLGVLPLIVL TQLGIIVGLG ILLDTFVVRT
LVIPALFALL GDRIWWPSAP RPAKAAATQA ENQPERSIP
//
