ID A0A1A3BB21_9MYCO Unreviewed; 632 AA.
AC A0A1A3BB21;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=Acetoacetate-CoA ligase {ECO:0000313|EMBL:OBI72110.1};
GN ORFNames=A5663_08460 {ECO:0000313|EMBL:OBI72110.1};
OS Mycobacterium sp. E740.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycobacterium.
OX NCBI_TaxID=1834149 {ECO:0000313|EMBL:OBI72110.1, ECO:0000313|Proteomes:UP000092151};
RN [1] {ECO:0000313|Proteomes:UP000092151}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=E740 {ECO:0000313|Proteomes:UP000092151};
RA Sutton G., Brinkac L., Sanka R., Adams M., Lau E., Sam S., Sreng N.,
RA Him V., Kerleguer A., Cheng S.;
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OBI72110.1}.
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DR EMBL; LZKP01000214; OBI72110.1; -; Genomic_DNA.
DR RefSeq; WP_068153617.1; NZ_LZKP01000214.1.
DR AlphaFoldDB; A0A1A3BB21; -.
DR STRING; 1834149.A5663_08460; -.
DR OrthoDB; 9803968at2; -.
DR Proteomes; UP000092151; Unassembled WGS sequence.
DR GO; GO:0030729; F:acetoacetate-CoA ligase activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR005914; Acac_CoA_synth.
DR InterPro; IPR032387; ACAS_N.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR NCBIfam; TIGR01217; ac_ac_CoA_syn; 1.
DR PANTHER; PTHR42921; ACETOACETYL-COA SYNTHETASE; 1.
DR PANTHER; PTHR42921:SF1; ACETOACETYL-COA SYNTHETASE; 1.
DR Pfam; PF16177; ACAS_N; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000313|EMBL:OBI72110.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000092151}.
FT DOMAIN 37..88
FT /note="Acetyl-coenzyme A synthetase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16177"
FT DOMAIN 95..452
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 519..594
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 632 AA; 68346 MW; 852FAB4895D71047 CRC64;
MTTAPQWTPT DADIADARVT DFAQFVRGRT GKDLADYRSL WEWSIDDPGA FWAALWDYFD
LGERPDTVLT SAEMPGAQWF PRTTLNYVDQ VVRNARSDRP AIVYLTEGGG RTEVSWSELL
SRTAEFAHRL QSIGVTAGDR VIGYLPNIPE AVIAFLASAS IGAVWSACGQ DYSAKAALDR
LGQLEPTVLV TTDGYTYGGK FHDKSADIAV LQDGLPTLRA TVMASELTGA ADGAGLTTTP
VDFAHPLWIL FSSGTTGLPK GMMHGHGGVL LEHLKAIALQ ADIGPDDTFF WYTSPSWMMW
NFQVAGLLVG ATIVCYDGSP SAPRTDALWD LAAGVKATVL GTSPGYVLAC AKAGAVPAKE
HDLSALRTVG ITGASLPPSS SLWLRDNVGG HVQVSSISGG TDVVSAFIGG VRTVPVWPGE
LSAPYLGCAL DSWDESGKPV RNEVGELVIT KPLPSMPVGF WNDPDGSRYR AAYFEMFPGV
WRHGDWITIT DRGSVIVHGR SDSTLNRHGI RMGSADIYQA VERLPEIAEA LIIGVEQPDG
GYWMPLFVVL ASGTELTDDL CDRVKQTIRE EVSPRHVPDE IIAAPGVPHT RTGKKLEVPI
KKLFQGADPS KVVERSAVDD PDLLEWYVRH KR
//
