ID A0A1A3C4W2_9MYCO Unreviewed; 380 AA.
AC A0A1A3C4W2;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=AI-2E family transporter {ECO:0000313|EMBL:OBI82130.1};
GN ORFNames=A5663_01510 {ECO:0000313|EMBL:OBI82130.1};
OS Mycobacterium sp. E740.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycobacterium.
OX NCBI_TaxID=1834149 {ECO:0000313|EMBL:OBI82130.1, ECO:0000313|Proteomes:UP000092151};
RN [1] {ECO:0000313|Proteomes:UP000092151}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=E740 {ECO:0000313|Proteomes:UP000092151};
RA Sutton G., Brinkac L., Sanka R., Adams M., Lau E., Sam S., Sreng N.,
RA Him V., Kerleguer A., Cheng S.;
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86)
CC family. {ECO:0000256|ARBA:ARBA00009773}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OBI82130.1}.
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DR EMBL; LZKP01000057; OBI82130.1; -; Genomic_DNA.
DR RefSeq; WP_068144971.1; NZ_LZKP01000057.1.
DR AlphaFoldDB; A0A1A3C4W2; -.
DR STRING; 1834149.A5663_01510; -.
DR OrthoDB; 9784366at2; -.
DR Proteomes; UP000092151; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR002549; AI-2E-like.
DR PANTHER; PTHR21716; TRANSMEMBRANE PROTEIN; 1.
DR PANTHER; PTHR21716:SF75; TRANSPORT PROTEIN SLL0063-RELATED; 1.
DR Pfam; PF01594; AI-2E_transport; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000092151};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 20..38
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 45..64
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 159..184
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 220..244
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 250..274
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 281..298
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 318..345
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 361..380
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 380 AA; 39949 MW; D2A293C2188F5A6B CRC64;
MPEGVSLDDE AVSPLVRKAA AWSWRLLLIF AAIFVLLWTI KRLEIIVVPV ALATMLAALL
MPAVDSAPLV NFSWLSRRAW IAASPERSIC SRLSPSGPSI SQVRTPSMLR LTWLVNSGAP
SMNWLIDGPL GLSREQIERS GDAAIQALRD NQEKLTSGAL STAGTVTEIV TGALLVLFTL
IFLLQGGRNI YAFITRIFPS DVRERVRDAG RAGFHSLIGY IRATFLVALV DAIGIGTGLA
IMGVPLALPL ASLVFLGAFV PLVGAVVTGF LAVIVALIAK GMIYALITLG LIIAVQQLEG
HVLQPLVMGR AVSIHPLAIV LVIAGGGVLA GIVGALLAVP TLAFLNSAVR VLTAPNPDAE
AAALESDDGP LVKAESDDVD
//
