ID A0A1A3IHM2_9MYCO Unreviewed; 340 AA.
AC A0A1A3IHM2;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 24-JAN-2024, entry version 27.
DE SubName: Full=6-phosphogluconate dehydrogenase (Decarboxylating) {ECO:0000313|EMBL:OBJ59379.1};
GN ORFNames=A9W95_11240 {ECO:0000313|EMBL:OBJ59379.1};
OS Mycobacterium sp. 1423905.2.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycobacterium.
OX NCBI_TaxID=1856859 {ECO:0000313|EMBL:OBJ59379.1, ECO:0000313|Proteomes:UP000092291};
RN [1] {ECO:0000313|Proteomes:UP000092291}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1423905.2 {ECO:0000313|Proteomes:UP000092291};
RA Sutton G., Brinkac L., Sanka R., Adams M., Lau E., Garcia-Basteiro A.,
RA Lopez-Varela E., Palencia S.;
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the 6-phosphogluconate dehydrogenase family.
CC {ECO:0000256|ARBA:ARBA00008419}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OBJ59379.1}.
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DR EMBL; LZLE01000065; OBJ59379.1; -; Genomic_DNA.
DR RefSeq; WP_067409327.1; NZ_LZLE01000065.1.
DR AlphaFoldDB; A0A1A3IHM2; -.
DR Proteomes; UP000092291; Unassembled WGS sequence.
DR GO; GO:0050661; F:NADP binding; IEA:InterPro.
DR GO; GO:0004616; F:phosphogluconate dehydrogenase (decarboxylating) activity; IEA:InterPro.
DR GO; GO:0019521; P:D-gluconate metabolic process; IEA:UniProtKB-KW.
DR GO; GO:0016054; P:organic acid catabolic process; IEA:UniProt.
DR GO; GO:0006098; P:pentose-phosphate shunt; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR004849; 6DGDH_YqeC.
DR InterPro; IPR013328; 6PGD_dom2.
DR InterPro; IPR006114; 6PGDH_C.
DR InterPro; IPR006115; 6PGDH_NADP-bd.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR006183; Pgluconate_DH.
DR NCBIfam; TIGR00872; gnd_rel; 1.
DR PANTHER; PTHR11811; 6-PHOSPHOGLUCONATE DEHYDROGENASE; 1.
DR PANTHER; PTHR11811:SF67; 6-PHOSPHOGLUCONATE DEHYDROGENASE YQEC-RELATED; 1.
DR Pfam; PF00393; 6PGD; 1.
DR Pfam; PF03446; NAD_binding_2; 1.
DR PRINTS; PR00076; 6PGDHDRGNASE.
DR SMART; SM01350; 6PGD; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW Gluconate utilization {ECO:0000256|ARBA:ARBA00023064}.
FT DOMAIN 186..335
FT /note="6-phosphogluconate dehydrogenase C-terminal"
FT /evidence="ECO:0000259|SMART:SM01350"
SQ SEQUENCE 340 AA; 36331 MW; EE1AE2CA862A8476 CRC64;
MQLGMIGLGR MGANIARRVT DDGHECVVYD HNPDAVKAMA GEKNMTGANS LEELRDKLSA
PRVVWVMVPA GTITTGVIDD LAKTLESGDI VIDGGNTYYR DDIKHAKTLS DNGIHLLDCG
TSGGVWGRER GYCLMIGGDA EAVAHAEPIF ASVAPGVDAA PRTPGRDGEV AQAEKGYLHC
GQSGAGHFVK MIHNGIEYGM MASLAEGLNI LRNADIGTRI QQGDAETAPL TYPECYQYNF
DIPDVAEVWR RGSVIGSWLL DLTASALHES PDLKEFSGRV SDSGEGRWTS IAAIDEGVPS
PVLTTALQSR FASRDLDDFA NKALSAMRKQ FGGHAEKPAN
//
