ID A0A1A3QL86_9MYCO Unreviewed; 412 AA.
AC A0A1A3QL86;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 24-JAN-2024, entry version 39.
DE RecName: Full=DNA (cytosine-5-)-methyltransferase {ECO:0000256|ARBA:ARBA00011975};
DE EC=2.1.1.37 {ECO:0000256|ARBA:ARBA00011975};
GN ORFNames=A5655_09265 {ECO:0000313|EMBL:OBK46865.1};
OS Mycobacterium sp. 1081908.1.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycobacterium.
OX NCBI_TaxID=1834066 {ECO:0000313|EMBL:OBK46865.1, ECO:0000313|Proteomes:UP000092324};
RN [1] {ECO:0000313|Proteomes:UP000092324}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1081908.1 {ECO:0000313|Proteomes:UP000092324};
RA Sutton G., Brinkac L., Sanka R., Adams M., Lau E., Garcia-Basteiro A.,
RA Lopez-Varela E., Palencia S.;
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the class I-like SAM-binding methyltransferase
CC superfamily. C5-methyltransferase family. {ECO:0000256|PROSITE-
CC ProRule:PRU01016}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OBK46865.1}.
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DR EMBL; LZLY01000104; OBK46865.1; -; Genomic_DNA.
DR RefSeq; WP_067011977.1; NZ_LZLY01000104.1.
DR AlphaFoldDB; A0A1A3QL86; -.
DR STRING; 1834066.A5655_09265; -.
DR OrthoDB; 9813719at2; -.
DR Proteomes; UP000092324; Unassembled WGS sequence.
DR GO; GO:0003886; F:DNA (cytosine-5-)-methyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0009307; P:DNA restriction-modification system; IEA:UniProtKB-KW.
DR Gene3D; 3.90.120.10; DNA Methylase, subunit A, domain 2; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR018117; C5_DNA_meth_AS.
DR InterPro; IPR001525; C5_MeTfrase.
DR InterPro; IPR031303; C5_meth_CS.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR10629; CYTOSINE-SPECIFIC METHYLTRANSFERASE; 1.
DR PANTHER; PTHR10629:SF52; DNA (CYTOSINE-5)-METHYLTRANSFERASE 1; 1.
DR Pfam; PF00145; DNA_methylase; 2.
DR PRINTS; PR00105; C5METTRFRASE.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS00094; C5_MTASE_1; 1.
DR PROSITE; PS00095; C5_MTASE_2; 1.
DR PROSITE; PS51679; SAM_MT_C5; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603, ECO:0000256|PROSITE-
KW ProRule:PRU01016}; Restriction system {ECO:0000256|ARBA:ARBA00022747};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691,
KW ECO:0000256|PROSITE-ProRule:PRU01016};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|PROSITE-
KW ProRule:PRU01016}.
FT ACT_SITE 105
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01016"
SQ SEQUENCE 412 AA; 45721 MW; 17310ADD9BA6D77E CRC64;
MTVVGRKHAG GRGVLRVGTS IELFTGTGGL ALAMHRAGFR HQLAVEVDRR ACATLLANVA
SDVDAGTLLL QDSNDLWPLV EGDIRKVDFT PLEGKADVVA GGVPCQPWSL GGVHRGFDDS
RNMWPELFRC VREVRPRAVI AENVKGLLRP SFRPYYDYIL RELAAPFEQR IEGEEWFDHD
KRLVKALKTD GVDPTERYDV HFRLVNAADY GVPQQRWRVF VVAFRRDLGL GGWKFPKSTH
SESALLHEQM SGEYWADHDI APRAPGADLT RAGLPPDDGL ARWQTLRDAI GDLPEPIGYK
VDHPSWLHHV GWPGARIYAG HTPNELDRPA KTVKAGVHGV PGGESVLRKD DGAIRYLTVR
EVARIMTFPD NWWLAGPRGE QMRQLGNAVP VELGLVMANA VAKALRSTKI VN
//
