ID A0A1A5NVM5_9ACTN Unreviewed; 758 AA.
AC A0A1A5NVM5;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Serine/threonine protein kinase {ECO:0000313|EMBL:OBQ46897.1};
GN ORFNames=A4U61_16015 {ECO:0000313|EMBL:OBQ46897.1};
OS Streptomyces sp. H-KF8.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1727216 {ECO:0000313|EMBL:OBQ46897.1, ECO:0000313|Proteomes:UP000093719};
RN [1] {ECO:0000313|Proteomes:UP000093719}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=H-KF8 {ECO:0000313|Proteomes:UP000093719};
RA Undabarrena A., Ugalde J.A., Seeger M., Camara B.;
RL Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OBQ46897.1}.
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DR EMBL; LWAB01000011; OBQ46897.1; -; Genomic_DNA.
DR RefSeq; WP_065002467.1; NZ_LWAB01000011.1.
DR AlphaFoldDB; A0A1A5NVM5; -.
DR OrthoDB; 9762169at2; -.
DR Proteomes; UP000093719; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd14014; STKc_PknB_like; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 2.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR017441; Protein_kinase_ATP_BS.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR PANTHER; PTHR46082:SF6; AAA+ ATPASE DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR PANTHER; PTHR46082; ATP/GTP-BINDING PROTEIN-RELATED; 1.
DR Pfam; PF00069; Pkinase; 1.
DR Pfam; PF13374; TPR_10; 2.
DR Pfam; PF13424; TPR_12; 3.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR SUPFAM; SSF48452; TPR-like; 3.
DR PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|PROSITE-ProRule:PRU10141};
KW Kinase {ECO:0000313|EMBL:OBQ46897.1};
KW Nucleotide-binding {ECO:0000256|PROSITE-ProRule:PRU10141};
KW Reference proteome {ECO:0000313|Proteomes:UP000093719};
KW Serine/threonine-protein kinase {ECO:0000313|EMBL:OBQ46897.1};
KW Transferase {ECO:0000313|EMBL:OBQ46897.1}.
FT DOMAIN 11..287
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT REGION 291..351
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 40
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10141"
SQ SEQUENCE 758 AA; 82444 MW; 4F0EE462F20C76D1 CRC64;
MGDGRLLHDR YRLVDPIGRG GMGEVWRARD ESLGREVAVK CLKPAGAQYD HAFGRVLRER
FRREARVAAS LQHRGITVVH DFGEYDGVLY LVMELLQGRD LSRLLEDNKQ HPLPVDEVVE
IAEQVAAALA YTHDQGIVHR DLKPANIVRL TDGTVKICDF GIARLGHDIG FTSRLTGTGV
AMGTPHYMSP EQISGTDVDR RSDLYSFGCV LYEIATGVPP FDLGDAWAVL VGHRDTPPRP
PRGLRAELPE RLERIILDLL AKEPGGRPDS ARELARRIGA LRAAPPLPAA VTARPRPVGA
PGAGGPAAPL PPAARTEPVG RAPRLPSWTR GMTTGRKAAF GGPRTAPPDP AAGLSGEWIA
RPAAGRGGPP PAQERPAPAP EALAALTGRH NAGLSLGRLG RWTEAGEVHR AVAAEREHLL
GPHHPDTLAS RYEVAFTLSR TGRAADALRA YKHVAEARIR TLGSEHPDTL AVRQEMAYVL
ARSGRPLDAH QVYLSVLSAR ERTMGADHPE TLRCRHNLAF NLGRLGRLED SYSTACEVAA
ARARVLGPEH PDTLVTRYEV AHTLGQLGRW AEALETYREV AEARARALGP DHTDTLAARY
EIGIGLGRLG RTAQALDLYR SLVDDRTRAQ GPTHPETLRA RHGLGINLGR LGRWVEALAE
SRAVCALRES TLGADHPDTL VSRREVAVGL GWLGRWEDAL TEYRRVADTR ERLLGADHRD
TLAARNDEAH CLERLGHGDV ATGPYREVAA PKQRRAAG
//
