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Database: UniProt
Entry: A0A1A5RCI5_9RHIZ
LinkDB: A0A1A5RCI5_9RHIZ
Original site: A0A1A5RCI5_9RHIZ 
ID   A0A1A5RCI5_9RHIZ        Unreviewed;       363 AA.
AC   A0A1A5RCI5;
DT   05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2016, sequence version 1.
DT   08-MAY-2019, entry version 11.
DE   RecName: Full=Phospho-2-dehydro-3-deoxyheptonate aldolase {ECO:0000256|PIRNR:PIRNR001361};
DE            EC=2.5.1.54 {ECO:0000256|PIRNR:PIRNR001361};
GN   ORFNames=A9K71_10405 {ECO:0000313|EMBL:OBQ77424.1};
OS   Mesorhizobium sp. WSM3873.
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales;
OC   Phyllobacteriaceae; Mesorhizobium.
OX   NCBI_TaxID=1854056 {ECO:0000313|EMBL:OBQ77424.1, ECO:0000313|Proteomes:UP000092385};
RN   [1] {ECO:0000313|EMBL:OBQ77424.1, ECO:0000313|Proteomes:UP000092385}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=WSM3873 {ECO:0000313|EMBL:OBQ77424.1,
RC   ECO:0000313|Proteomes:UP000092385};
RA   Lavstsen T., Jespersen J.S.;
RL   Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Stereospecific condensation of phosphoenolpyruvate (PEP)
CC       and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-
CC       arabino-heptulosonate-7-phosphate (DAHP).
CC       {ECO:0000256|PIRNR:PIRNR001361}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=D-erythrose 4-phosphate + H2O + phosphoenolpyruvate = 7-
CC         phospho-2-dehydro-3-deoxy-D-arabino-heptonate + phosphate;
CC         Xref=Rhea:RHEA:14717, ChEBI:CHEBI:15377, ChEBI:CHEBI:16897,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:58394, ChEBI:CHEBI:58702;
CC         EC=2.5.1.54; Evidence={ECO:0000256|PIRNR:PIRNR001361};
CC   -!- PATHWAY: Metabolic intermediate biosynthesis; chorismate
CC       biosynthesis; chorismate from D-erythrose 4-phosphate and
CC       phosphoenolpyruvate: step 1/7. {ECO:0000256|PIRNR:PIRNR001361}.
CC   -!- SIMILARITY: Belongs to the class-I DAHP synthase family.
CC       {ECO:0000256|PIRNR:PIRNR001361}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:OBQ77424.1}.
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DR   EMBL; LYTM01000055; OBQ77424.1; -; Genomic_DNA.
DR   RefSeq; WP_067002870.1; NZ_LYTM01000055.1.
DR   EnsemblBacteria; OBQ77424; OBQ77424; A9K71_10405.
DR   UniPathway; UPA00053; UER00084.
DR   Proteomes; UP000092385; Unassembled WGS sequence.
DR   GO; GO:0003849; F:3-deoxy-7-phosphoheptulonate synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0009073; P:aromatic amino acid family biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0009423; P:chorismate biosynthetic process; IEA:UniProtKB-UniPathway.
DR   Gene3D; 3.20.20.70; -; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR006218; DAHP1/KDSA.
DR   InterPro; IPR006219; DHAP_synth_1.
DR   PANTHER; PTHR21225; PTHR21225; 1.
DR   Pfam; PF00793; DAHP_synth_1; 1.
DR   PIRSF; PIRSF001361; DAHP_synthase; 1.
DR   TIGRFAMs; TIGR00034; aroFGH; 1.
PE   3: Inferred from homology;
KW   Amino-acid biosynthesis {ECO:0000256|PIRNR:PIRNR001361};
KW   Aromatic amino acid biosynthesis {ECO:0000256|PIRNR:PIRNR001361};
KW   Complete proteome {ECO:0000313|Proteomes:UP000092385};
KW   Transferase {ECO:0000256|PIRNR:PIRNR001361,
KW   ECO:0000256|SAAS:SAAS00080156}.
FT   DOMAIN       42    338       DAHP_synth_1. {ECO:0000259|Pfam:PF00793}.
SQ   SEQUENCE   363 AA;  38608 MW;  21949A5948BF06F4 CRC64;
     MLTTTDDLRV KELKVLSTPD DVMREIPRSL TATRTVAASR NAIHSILTGA DDRLVVIVGP
     CSIHDPVAAV DYASRLAALR EALADRLEIV MRVYFEKPRT TVGWKGLIND PDLDGSFNID
     KGLRMARNVL SAVNNLGLPA ATEFLDMTTP QYIADLVAWG AIGARTTESQ IHRELASGLS
     CPVGFKNGTD GNLRIAGEAV KSAAQPHHFM AVTKGGRSAI AATTGNEDCH IILRGGVAPN
     YDAASVDAAA AELGRIGIAP RLMIDVSHAN SGKKPENQPK VAHDVAGQVA AGDERIIGVM
     IESNLVAGRQ DVVPSKQLTY GQSITDGCID WATTETVLHG LAGAVEWRRS VKRELLATRQ
     GAA
//
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