ID A0A1A6A105_9TREE Unreviewed; 711 AA.
AC A0A1A6A105;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 13-SEP-2023, entry version 27.
DE RecName: Full=U3 small nucleolar RNA-associated protein 25 {ECO:0000256|ARBA:ARBA00015422, ECO:0000256|RuleBase:RU365070};
DE Short=U3 snoRNA-associated protein 25 {ECO:0000256|RuleBase:RU365070};
GN ORFNames=I303_06019 {ECO:0000313|EMBL:OBR83739.1};
OS Kwoniella dejecticola CBS 10117.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Tremellomycetes;
OC Tremellales; Cryptococcaceae; Kwoniella.
OX NCBI_TaxID=1296121 {ECO:0000313|EMBL:OBR83739.1, ECO:0000313|Proteomes:UP000078595};
RN [1] {ECO:0000313|EMBL:OBR83739.1, ECO:0000313|Proteomes:UP000078595}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 10117 {ECO:0000313|EMBL:OBR83739.1,
RC ECO:0000313|Proteomes:UP000078595};
RG The Broad Institute Genome Sequencing Platform;
RA Cuomo C., Litvintseva A., Chen Y., Heitman J., Sun S., Springer D.,
RA Dromer F., Young S.K., Zeng Q., Gargeya S., Fitzgerald M., Abouelleil A.,
RA Alvarado L., Berlin A.M., Chapman S.B., Dewar J., Goldberg J., Griggs A.,
RA Gujja S., Hansen M., Howarth C., Imamovic A., Larimer J., McCowan C.,
RA Murphy C., Pearson M., Priest M., Roberts A., Saif S., Shea T., Sykes S.,
RA Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Cryptococcus dejecticola CBS10117.";
RL Submitted (JUL-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: DEAD-box RNA helicase-like protein required for pre-18S rRNA
CC processing, specifically at sites A0, A1, and A2.
CC {ECO:0000256|ARBA:ARBA00002883, ECO:0000256|RuleBase:RU365070}.
CC -!- SUBUNIT: Component of the ribosomal small subunit (SSU) processome
CC composed of at least 40 protein subunits and snoRNA U3.
CC {ECO:0000256|RuleBase:RU365070}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC {ECO:0000256|ARBA:ARBA00004604, ECO:0000256|RuleBase:RU365070}.
CC -!- SIMILARITY: Belongs to the UTP25 family.
CC {ECO:0000256|ARBA:ARBA00009223, ECO:0000256|RuleBase:RU365070}.
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DR EMBL; KI894033; OBR83739.1; -; Genomic_DNA.
DR RefSeq; XP_018261581.1; XM_018409308.1.
DR AlphaFoldDB; A0A1A6A105; -.
DR STRING; 1296121.A0A1A6A105; -.
DR GeneID; 28969718; -.
DR VEuPathDB; FungiDB:I303_06019; -.
DR OrthoDB; 5473087at2759; -.
DR Proteomes; UP000078595; Unassembled WGS sequence.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:1990904; C:ribonucleoprotein complex; IEA:UniProtKB-KW.
DR GO; GO:0034511; F:U3 snoRNA binding; IEA:InterPro.
DR GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
DR InterPro; IPR010678; UTP25.
DR PANTHER; PTHR12933; ORF PROTEIN-RELATED; 1.
DR PANTHER; PTHR12933:SF0; U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 25 HOMOLOG; 1.
DR Pfam; PF06862; UTP25; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU365070};
KW Reference proteome {ECO:0000313|Proteomes:UP000078595};
KW Ribonucleoprotein {ECO:0000256|ARBA:ARBA00023274,
KW ECO:0000256|RuleBase:RU365070};
KW Ribosome biogenesis {ECO:0000256|RuleBase:RU365070};
KW rRNA processing {ECO:0000256|RuleBase:RU365070}.
FT REGION 19..121
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 44..60
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 77..92
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 104..121
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 711 AA; 79352 MW; 8765F9BD57694640 CRC64;
MSTAQEIKLL TLLNVSAVKR PRELDIPGGH RGSPSFSKTP SLVLESEDGK EPKKRRKSVV
FGGEVGPSGS TYGKGKGKGK AKKDDDLIAV NGVKDSEVDT SNTGNDEVFE EEGESDDEAE
SSALANNDLF NVHFGAAPPI LTKEGVALAE EHKWKAERKS LKGFGRAVEL KTGASSTDGD
LRTRITPSIS AALKASSSSY PLLSTSLAHL GTYKDFYLHS LDGEADGTET QILGEQKEAM
RLAAVVHALN HVLKTRRKII RNNEKLAHAA ASDDSSSMPE PPRDQSFTRP KILLLLPFRS
LALHYIKTHL LPLAPAGTQI ENQRPFLTSF ALPEDEEDPL ASTSARDNYP LDHLVNFRGN
SDDNFRFGIK FTRKAWRIVM PPANEEKLLD CDILIASPLG FKMAAEREDS TDLLSSIEIL
IADGLDTMAM QNWEHVQFIF NNMNKIPKSP HGCDFSRVKP WYLESQAQYL RQTILLSRYD
TPETRALFNR NCQNLQGKVR LEKVDHHGVL DLVRPGVRQI FERIDIDGSK ALNGEAAVEE
VDNRVEWLTK KTIPALLRSA ISRQNTLIIV PSYFDFVRLN NYLRKNDAAT YAAISEYSSN
SEISKARTLF FKGKKSFLII TERLHFYRRY KIRGAKTVVF YSLPDHAQFY SEFMSTPFLG
SKGQGEVEVD EAEVSSRVLF SRFDALKLER VVGSGSARRM LTSGEGRFEF I
//
