ID A0A1A6A9B9_9TREE Unreviewed; 1759 AA.
AC A0A1A6A9B9;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE RecName: Full=Pre-rRNA-processing protein fhl1 {ECO:0008006|Google:ProtNLM};
GN ORFNames=I303_02662 {ECO:0000313|EMBL:OBR86652.1};
OS Kwoniella dejecticola CBS 10117.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Tremellomycetes;
OC Tremellales; Cryptococcaceae; Kwoniella.
OX NCBI_TaxID=1296121 {ECO:0000313|EMBL:OBR86652.1, ECO:0000313|Proteomes:UP000078595};
RN [1] {ECO:0000313|EMBL:OBR86652.1, ECO:0000313|Proteomes:UP000078595}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 10117 {ECO:0000313|EMBL:OBR86652.1,
RC ECO:0000313|Proteomes:UP000078595};
RG The Broad Institute Genome Sequencing Platform;
RA Cuomo C., Litvintseva A., Chen Y., Heitman J., Sun S., Springer D.,
RA Dromer F., Young S.K., Zeng Q., Gargeya S., Fitzgerald M., Abouelleil A.,
RA Alvarado L., Berlin A.M., Chapman S.B., Dewar J., Goldberg J., Griggs A.,
RA Gujja S., Hansen M., Howarth C., Imamovic A., Larimer J., McCowan C.,
RA Murphy C., Pearson M., Priest M., Roberts A., Saif S., Shea T., Sykes S.,
RA Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Cryptococcus dejecticola CBS10117.";
RL Submitted (JUL-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00089}.
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DR EMBL; KI894029; OBR86652.1; -; Genomic_DNA.
DR RefSeq; XP_018264494.1; XM_018406000.1.
DR STRING; 1296121.A0A1A6A9B9; -.
DR GeneID; 28966361; -.
DR VEuPathDB; FungiDB:I303_02662; -.
DR OrthoDB; 5385885at2759; -.
DR Proteomes; UP000078595; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0060962; P:regulation of ribosomal protein gene transcription by RNA polymerase II; IEA:InterPro.
DR CDD; cd00059; FH_FOX; 1.
DR Gene3D; 2.60.200.20; -; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR000253; FHA_dom.
DR InterPro; IPR045178; Fhl1/FHA1.
DR InterPro; IPR001766; Fork_head_dom.
DR InterPro; IPR008984; SMAD_FHA_dom_sf.
DR InterPro; IPR030456; TF_fork_head_CS_2.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR21712:SF29; PRE-RRNA-PROCESSING PROTEIN FHL1; 1.
DR PANTHER; PTHR21712; UNCHARACTERIZED; 1.
DR Pfam; PF00498; FHA; 1.
DR Pfam; PF00250; Forkhead; 1.
DR PRINTS; PR00053; FORKHEAD.
DR SMART; SM00339; FH; 1.
DR SUPFAM; SSF49879; SMAD/FHA domain; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50006; FHA_DOMAIN; 1.
DR PROSITE; PS00658; FORK_HEAD_2; 1.
DR PROSITE; PS50039; FORK_HEAD_3; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00089};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00089}; Reference proteome {ECO:0000313|Proteomes:UP000078595}.
FT DOMAIN 411..456
FT /note="FHA"
FT /evidence="ECO:0000259|PROSITE:PS50006"
FT DOMAIN 1157..1254
FT /note="Fork-head"
FT /evidence="ECO:0000259|PROSITE:PS50039"
FT DNA_BIND 1157..1254
FT /note="Fork-head"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00089"
FT REGION 65..112
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 200..223
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 288..315
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 350..371
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 391..411
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 565..683
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 701..1110
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1239..1278
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1423..1514
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1571..1759
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 70..95
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 200..221
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 295..312
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 393..408
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 573..591
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 707..789
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 805..823
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 849..916
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 993..1013
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1040..1106
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1240..1278
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1433..1465
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1578..1626
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1670..1692
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1705..1745
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1759 AA; 182572 MW; 64B9AAB5079C98DF CRC64;
MSEQYVLNNN AYQLDDQYNY AGATVGAGPS NPTTTATAMF SPGDGGDFSG PAPMSTPMPM
PMRSMGQDVF SSAAGPSNSN MNSTGQGQGQ GLGQGPNQWY PPIPSLASLP VDKSKTDPKP
AYYKLQFGDE VTGFSYYVRT LAVMIGRNVD RHGSALPPPS ITAPSVPINP PLDPNQPSPP
LIASVEDIMM PQIALAEFPT PPLPPAHTSF SVPPQSPPHP SSAPLSTTFL NDGFAVPPRA
QSEGMIDHAG PPDLSFLQDE DYPDIDMGGF GVLEELAEAV RAESIKAASM ERSVEPDSRM
SQSLSIPPNG SQEGGLSDFM VKLEEGVKAE SAELDFIGTG DRQIPIVIDE PSGSAGPQAM
EVDHSQSQSQ RQVMNDISAM DMDLSQVKLE HLDDLPPPPP PPPPKSSAPV EHVDVDLGPL
KSVSRNHAKI EYKADLGHFC LEIFGRNGAW VDDRYFVKGS IVPLAQGSQI QIATRIFSFV
LPPSPVSSPT YTHYALDGVT PEIAEDLPYP YNLPPSEVGY HEFYGEPGPG PSSAASMAAR
APPAFNAFAA ADGYGLGIEG VGENSWVGWG SDDDDGGDSE EDEEELDESG EEWEPSPPKS
VKPKKTKMKS KASKGGLVPG EEESELSSVA SEGEDTKKKP KKQTLPATAP TTTSHVIRPK
PIAPAPAPSQ IVPPPIAASI TAPGQLPTTI APADMILPPA DVKAAESRKS SVADNPKANK
DAEGKLTSPK KVKKKKDKDK EKEKEKEMDK AQDKGKAQDK DKDETQGKDK NKPEDKAGNT
KDNEPKTGDV VVDKNTIQAT DNATKVNETK DKSAADGAKG DDPKKKKKKK KPKPDEDTVK
VEAVDTTAIN GDGKEKDKDA AAATPKKAKK SKNAEVDKTA GAAEDIKPEI SEKKKKKKKP
KADADADGKA ADGKADSAKQ LDTPAVPAEP PTLAAALPPP ATVGTAASAA QPMPTLAAAM
GPTSTPKPPN AVSAASHQPA AQPPPAPITQ RPGQQLAPVQ PGQPGQPTHV QAGQSIPVRP
PMPGVRPPSQ LQLPNGQHVR PPIPGQPQTP PNYPPGQVPH PQHQPVGPGQ PHPSQIARPP
PFGHPMQPQN RSTPPAAPPS PVPLPPFYCT ELNETPGQPG HIIVNVPIPP SGAGPRPPPG
PLLGLDGNVF IGPPPLKPTQ TFATIIHRSL QCLPRGRGTL GEVCNWVAGE WEWFRLNVDS
GWQNSIRHNL SLNKAFLKVP RIPEDDPESK GSVWIIDPEE GPLFEEKQKK DAQKSASKDK
NAESRREKER IRAEERAKKQ REAAIEAARN PPQMIQRTIP VAPRPIPRPV PVAQPAAPPA
PPAPVSANAK GILQPKAKIV VVMQPITAAM RARSVISTTD ANGNLLPFVC DGTTLVLDQS
TFGHLTSDIM DKLTLLGAAG AVDVLSAWVI NKNKQQATKA AQAKAGTGAT AGVKNGMTAN
TTGSAKPGVS SATSTSATTS AARPLAATPT AAATANKPSA PAAATPGAPA KPVVGAKPAV
NSATGKPIPG PAPPGTSLTK VIGMIAAVAN AKGDVNTVGP NASALLRYIR VVGVDIDLRV
AERIWATGVV PPLPQKKAPT KSNASGTNAA NGNATTAKAA TPAHTTNPSA KPGSASNAVS
ASKVPSPAGP TPSPASATSA LKPPAPTVSA APAINKSPAP APASAPLSQA EAAVPNTNKA
SVGASPTATA VSTGVKRKLE DGDDNVSALS STKGTGTGSS ASNPIVIGGS AGASGSNTIL
GASGEQQENK KPRLETSGA
//
