ID   A0A1A6AA83_9TREE        Unreviewed;      1041 AA.
AC   A0A1A6AA83;
DT   05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2016, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   RecName: Full=CNH domain-containing protein {ECO:0000259|PROSITE:PS50219};
GN   ORFNames=I303_02989 {ECO:0000313|EMBL:OBR86967.1};
OS   Kwoniella dejecticola CBS 10117.
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Tremellomycetes;
OC   Tremellales; Cryptococcaceae; Kwoniella.
OX   NCBI_TaxID=1296121 {ECO:0000313|EMBL:OBR86967.1, ECO:0000313|Proteomes:UP000078595};
RN   [1] {ECO:0000313|EMBL:OBR86967.1, ECO:0000313|Proteomes:UP000078595}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 10117 {ECO:0000313|EMBL:OBR86967.1,
RC   ECO:0000313|Proteomes:UP000078595};
RG   The Broad Institute Genome Sequencing Platform;
RA   Cuomo C., Litvintseva A., Chen Y., Heitman J., Sun S., Springer D.,
RA   Dromer F., Young S.K., Zeng Q., Gargeya S., Fitzgerald M., Abouelleil A.,
RA   Alvarado L., Berlin A.M., Chapman S.B., Dewar J., Goldberg J., Griggs A.,
RA   Gujja S., Hansen M., Howarth C., Imamovic A., Larimer J., McCowan C.,
RA   Murphy C., Pearson M., Priest M., Roberts A., Saif S., Shea T., Sykes S.,
RA   Wortman J., Nusbaum C., Birren B.;
RT   "The Genome Sequence of Cryptococcus dejecticola CBS10117.";
RL   Submitted (JUL-2013) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; KI894029; OBR86967.1; -; Genomic_DNA.
DR   RefSeq; XP_018264809.1; XM_018406315.1.
DR   AlphaFoldDB; A0A1A6AA83; -.
DR   STRING; 1296121.A0A1A6AA83; -.
DR   GeneID; 28966688; -.
DR   VEuPathDB; FungiDB:I303_02989; -.
DR   OrthoDB; 38195at2759; -.
DR   Proteomes; UP000078595; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR   GO; GO:0043231; C:intracellular membrane-bounded organelle; IEA:UniProt.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:UniProtKB-UniRule.
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
DR   InterPro; IPR000547; Clathrin_H-chain/VPS_repeat.
DR   InterPro; IPR001180; CNH_dom.
DR   InterPro; IPR032914; Vam6/VPS39/TRAP1.
DR   InterPro; IPR019452; VPS39/TGF_beta_rcpt-assoc_1.
DR   InterPro; IPR019453; VPS39/TGF_beta_rcpt-assoc_2.
DR   PANTHER; PTHR12894; CNH DOMAIN CONTAINING; 1.
DR   PANTHER; PTHR12894:SF27; TRANSFORMING GROWTH FACTOR-BETA RECEPTOR-ASSOCIATED PROTEIN 1; 1.
DR   Pfam; PF00637; Clathrin; 1.
DR   Pfam; PF10366; Vps39_1; 1.
DR   Pfam; PF10367; Vps39_2; 1.
DR   PROSITE; PS50236; CHCR; 1.
DR   PROSITE; PS50219; CNH; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000078595}.
FT   DOMAIN          14..356
FT                   /note="CNH"
FT                   /evidence="ECO:0000259|PROSITE:PS50219"
FT   REGION          537..557
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1041 AA;  113799 MW;  D5975A9CDE962BDE CRC64;
     MAGFSIHPLL PSVKAKITAI YQHDDRLYVG LASGSLQIHS YTIPKDDDKP KAELLKTHTL
     GKRPIDQIGI LGESKQIIIL SDTVVTLYSL PDLPKKSSIV LNQARSAHCF AHTTYLPKGL
     KKSSDSTLDN GMKDLLVVGC RKKVVVYGTG KGGLKEGWEL NLPHSPRTII FPSPPSTSLP
     ETIDLLFTPQ TSVLLHINPA SSANRLSVSD VTTSPPPPSS SASLIAEEGG STGITMGMGA
     LSGLGGYVGL GSKSAAPLGT RTVGGEVLLA RDGAFLSSEG NYTRTESLQW PGPPDALGFA
     NPYIYSVVPV LPSSSASTSS AIPIPTIQIH LAPTLILRQA LTLPSPSAGG LSVSHMMTTI
     KASPSTVPAE NMVSSTKMLV VSTPTDKQLS QAEGSSIWAL NSGEIGDEVD QLVKEGRVSD
     AIGLVEAVGE NGLSPSRRLP HLQTLQAVTQ MAKGEYQSAM ETFLIFNVNP ALILSLFPAE
     TISGRLHVPK DQWMELFGAV EGAKLAPHIE TDKEEGTARG ILKSVAGLGG LSKKGSINGL
     REMGDNASIR SGKSVDKNGE QEKVPIMKEE DGIAALEALM YFLSDRRQKL AGAISTNHLP
     PESEYPPLSS LSAKEQHNLP SIPFTELTPE QLLRVAQVIY TGLIKVYLVA RPILVGSLCR
     IENWCDVEEV EELLKAQKKF GDLIDLYQGK KMHGKALKML HELAKEEEDK LDRYPPTIRY
     LQKLGPSQLS LILKSSDWIF DEDPKMGLQI FTADEPEVES LPRSEVMQFL EKTNQEACIG
     YLEHVIHTLG EEGSDFHDKL AELYHARVKA EEGKNGSIEL RQEYYAKLLE FLEASKTYRP
     YRLISKLAAD EMPEARAFLL GRMGKHEEAL RIYVYRLEDY PQAELYCVRA YPTNDDIFLL
     LLRIYLRPSA NSGKEALLSP ALSLLSKYST SLPPSPVLDL LPPLVPMQEV DKFFLLTLRD
     THTKQNEARL LKNLVKGRNE ELDRLVLGLE GKRVRITDQR ICPQCHKRLG NSAIAVHSPR
     GEVTHLHCKD SFSAKLSKSR G
//