ID   A0A1A6ACH4_9TREE        Unreviewed;       792 AA.
AC   A0A1A6ACH4;
DT   05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2016, sequence version 1.
DT   24-JAN-2024, entry version 28.
DE   RecName: Full=Homeobox domain-containing protein {ECO:0000259|PROSITE:PS50071};
GN   ORFNames=I303_01967 {ECO:0000313|EMBL:OBR87755.1};
OS   Kwoniella dejecticola CBS 10117.
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Tremellomycetes;
OC   Tremellales; Cryptococcaceae; Kwoniella.
OX   NCBI_TaxID=1296121 {ECO:0000313|EMBL:OBR87755.1, ECO:0000313|Proteomes:UP000078595};
RN   [1] {ECO:0000313|EMBL:OBR87755.1, ECO:0000313|Proteomes:UP000078595}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 10117 {ECO:0000313|EMBL:OBR87755.1,
RC   ECO:0000313|Proteomes:UP000078595};
RG   The Broad Institute Genome Sequencing Platform;
RA   Cuomo C., Litvintseva A., Chen Y., Heitman J., Sun S., Springer D.,
RA   Dromer F., Young S.K., Zeng Q., Gargeya S., Fitzgerald M., Abouelleil A.,
RA   Alvarado L., Berlin A.M., Chapman S.B., Dewar J., Goldberg J., Griggs A.,
RA   Gujja S., Hansen M., Howarth C., Imamovic A., Larimer J., McCowan C.,
RA   Murphy C., Pearson M., Priest M., Roberts A., Saif S., Shea T., Sykes S.,
RA   Wortman J., Nusbaum C., Birren B.;
RT   "The Genome Sequence of Cryptococcus dejecticola CBS10117.";
RL   Submitted (JUL-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC       ECO:0000256|PROSITE-ProRule:PRU00108, ECO:0000256|RuleBase:RU000682}.
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DR   EMBL; KI894028; OBR87755.1; -; Genomic_DNA.
DR   RefSeq; XP_018265597.1; XM_018405316.1.
DR   AlphaFoldDB; A0A1A6ACH4; -.
DR   STRING; 1296121.A0A1A6ACH4; -.
DR   GeneID; 28965666; -.
DR   VEuPathDB; FungiDB:I303_01967; -.
DR   OrthoDB; 2908004at2759; -.
DR   Proteomes; UP000078595; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:InterPro.
DR   CDD; cd00086; homeodomain; 1.
DR   Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR017970; Homeobox_CS.
DR   InterPro; IPR001356; Homeobox_dom.
DR   PANTHER; PTHR24324:SF5; HEMATOPOIETICALLY-EXPRESSED HOMEOBOX PROTEIN HHEX; 1.
DR   PANTHER; PTHR24324; HOMEOBOX PROTEIN HHEX; 1.
DR   Pfam; PF00046; Homeodomain; 1.
DR   SMART; SM00389; HOX; 1.
DR   SUPFAM; SSF46689; Homeodomain-like; 1.
DR   PROSITE; PS00027; HOMEOBOX_1; 1.
DR   PROSITE; PS50071; HOMEOBOX_2; 1.
PE   4: Predicted;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW   ProRule:PRU00108};
KW   Homeobox {ECO:0000256|ARBA:ARBA00023155, ECO:0000256|PROSITE-
KW   ProRule:PRU00108};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW   ProRule:PRU00108}; Reference proteome {ECO:0000313|Proteomes:UP000078595}.
FT   DOMAIN          142..202
FT                   /note="Homeobox"
FT                   /evidence="ECO:0000259|PROSITE:PS50071"
FT   DNA_BIND        144..203
FT                   /note="Homeobox"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00108"
FT   REGION          199..251
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          417..452
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          517..544
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          562..778
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        199..220
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        221..236
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        562..709
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        716..773
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   792 AA;  84921 MW;  6069DC6919FAE07B CRC64;
     MSVPLPHGYI PNPNEVFIDQ SQAQAGPSNY ARPPAQGVPA HLQGPPPQTP FYPVNGHMPT
     GFPPQMEQIQ HIPQQQYMPQ YTTSGIIPHI QPGFAYPGME VNGGAAVVPN FHFGSIPQNP
     PYMDEWTDGG MPHEGQEMVY SNLEVKHRRR TTPDQLKILE YWYDINPKPD NALREHLAAQ
     LGMTKRNVQV WFQNRRAKMK GLAKKDEKGD NEEEEKTPEK SSPSQQQPQP QQRVPRPTLI
     TPMGPPMGPP PMARRASLAN GEAAKIEMFV AKRAAAAANG LNRGLRPPGF VSPQRSPLMG
     QAFAARRQSI PYPTPITAGP NGGPNVNGPG PSPKISPVVR VMPSALHLTA MRNNTRRASM
     PGAAQLISSG PFTPPRVITN QHQVGLPREL STIKDDDSHH VGADGTQAQQ QLFSPANQSA
     GYDQSIPFSP NSPLPNPAFS FGTEGHQQLQ GQGVQHLNQV PILDEAEAAR QQQLFLAFQQ
     RGRMGSIASI GTYATDNGNG TDLEDTSLGE WLAQESNSGL GVLPNGQPQG QEGPDGFDPD
     ARRSSAPADL LHQIGIMGLN NTQIRPSPLG THFTPDNYLP QGSGSTSTFE ANQLSTNKMG
     LTSADLDPSP ISMSSMPSSS SGGVSPTDHH LFGQSQSHGS LNFQQNASTG AHHQPVRSIS
     LQQFPPSNLS ANDSGSNNTI LPHGQAHSHS NSSVSPYSDH SSAPPEYAQQ MIGQPNGLFE
     GYQQPASAQP SGGATLNHST SIPMSNSAHQ QAGQGQGQAQ GQGQRQNALS NEGKDDFSFL
     EGLNGETVDI LV
//