ID A0A1A6AGI4_9TREE Unreviewed; 1401 AA.
AC A0A1A6AGI4;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:OBR89185.1};
GN ORFNames=I303_01009 {ECO:0000313|EMBL:OBR89185.1};
OS Kwoniella dejecticola CBS 10117.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Tremellomycetes;
OC Tremellales; Cryptococcaceae; Kwoniella.
OX NCBI_TaxID=1296121 {ECO:0000313|EMBL:OBR89185.1, ECO:0000313|Proteomes:UP000078595};
RN [1] {ECO:0000313|EMBL:OBR89185.1, ECO:0000313|Proteomes:UP000078595}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 10117 {ECO:0000313|EMBL:OBR89185.1,
RC ECO:0000313|Proteomes:UP000078595};
RG The Broad Institute Genome Sequencing Platform;
RA Cuomo C., Litvintseva A., Chen Y., Heitman J., Sun S., Springer D.,
RA Dromer F., Young S.K., Zeng Q., Gargeya S., Fitzgerald M., Abouelleil A.,
RA Alvarado L., Berlin A.M., Chapman S.B., Dewar J., Goldberg J., Griggs A.,
RA Gujja S., Hansen M., Howarth C., Imamovic A., Larimer J., McCowan C.,
RA Murphy C., Pearson M., Priest M., Roberts A., Saif S., Shea T., Sykes S.,
RA Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Cryptococcus dejecticola CBS10117.";
RL Submitted (JUL-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the sorting nexin family.
CC {ECO:0000256|ARBA:ARBA00010883}.
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DR EMBL; KI894027; OBR89185.1; -; Genomic_DNA.
DR RefSeq; XP_018267027.1; XM_018404373.1.
DR STRING; 1296121.A0A1A6AGI4; -.
DR GeneID; 28964708; -.
DR VEuPathDB; FungiDB:I303_01009; -.
DR OrthoDB; 5392990at2759; -.
DR Proteomes; UP000078595; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0043226; C:organelle; IEA:UniProt.
DR GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR Gene3D; 3.30.1520.10; Phox-like domain; 1.
DR Gene3D; 1.10.167.10; Regulator of G-protein Signalling 4, domain 2; 1.
DR InterPro; IPR003114; Phox_assoc.
DR InterPro; IPR001683; PX_dom.
DR InterPro; IPR036871; PX_dom_sf.
DR InterPro; IPR016137; RGS.
DR InterPro; IPR036305; RGS_sf.
DR InterPro; IPR044926; RGS_subdomain_2.
DR InterPro; IPR013937; Sorting_nexin_C.
DR PANTHER; PTHR22775; SORTING NEXIN; 1.
DR PANTHER; PTHR22775:SF3; SORTING NEXIN-13; 1.
DR Pfam; PF08628; Nexin_C; 1.
DR Pfam; PF00787; PX; 1.
DR Pfam; PF02194; PXA; 1.
DR Pfam; PF00615; RGS; 1.
DR SMART; SM00312; PX; 1.
DR SMART; SM00313; PXA; 1.
DR SMART; SM00315; RGS; 1.
DR SUPFAM; SSF64268; PX domain; 1.
DR SUPFAM; SSF48097; Regulator of G-protein signaling, RGS; 1.
DR PROSITE; PS50195; PX; 1.
DR PROSITE; PS51207; PXA; 1.
DR PROSITE; PS50132; RGS; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000078595};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..25
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 32..53
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 112..291
FT /note="PXA"
FT /evidence="ECO:0000259|PROSITE:PS51207"
FT DOMAIN 455..604
FT /note="RGS"
FT /evidence="ECO:0000259|PROSITE:PS50132"
FT DOMAIN 1006..1135
FT /note="PX"
FT /evidence="ECO:0000259|PROSITE:PS50195"
FT REGION 315..344
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 631..776
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 835..864
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 655..718
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 743..765
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 835..849
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 850..864
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1401 AA; 154947 MW; 2E2D2D190F091B1C CRC64;
MSFFFANSFA FRISLVVLAF SLIFPRFKIL QTLLFTPMHI SSAVCLSISY VLWLTVRSDR
RVSPKATQPV ARTKHALRQL RFTTPAAWSA VLTRQAWEEN VLAYPPMNGD ASTSLNDRLN
SFLRLIRLHF ILPWYGRISA SPAFSHSVEG LLRHVIGDIT GRAENVDWPD MMVHKVLPII
SDHVQHYRSV EHLASTSAAA TPNPALPLPL PRKSHPALSH HPLTAAGTSP SIAAHLRGTL
ARIVERVIPQ QDQSEVVSTI VREIALGAVL LPVFEMLCDP DFWNRQIDEK GGRYLREREQ
VDKFLTALSA LPASSKTNTP LPSSKSHKFR KTPSTPSSTS ISANSSSKQF DAFLKSISKL
KTLGDARRLR ADVERELRTA KLVLADEVRR EENGKDGNKI LRRAQKYVQR LERAKVDIDH
RVGLLSGQPN NPRSSLERSP MSSMILEANS GEAVNLYSIL SDPSSLAYWL EHMDRRGRSR
LVQYWLTVEG FKDPLEVAGL NNATDGTSQS DKAKDNSPAH QTIAEDVAFL YEMYFAAGQS
EVGITAKHRT IIEEYAERSQ TSLSEIDAQI VKHAVFASQK EVYEMMVEDD WPSFKKGQLY
IKAVADLQRT GTTSPVLPSN AQLPAVLLPS FGAQSQPDRS GKRPPVKPIP HESSRSLFSL
LSPSLRSRQS NKQAENTPVG PPTPTASFHV SPPLVNRSSA EGTHFPLLLS SSASSPGAGG
HDDASVKISG LATPPPIERR SSHLDFLIAE GEDGDSPKER DRLFGGEEEE ENEDRLAEAQ
RIEAIQAALN DIIASDDMNS SRSVDRAHSA DLDEKLRSPA ASLVLFDRSP VKESKYSRLT
SKSAEDLKTA RTGKASSSAP ASRLPSVAVS DVKTLTKRRS TQKLSLSPEK TSKHIFDDEL
MDDDQVSLEG EEVDEANELI KLAEPGDLQL SVEIARLQDK ITELVQQDHL LDTLIRQAEL
TGNQAELRIL QRSQSSVRRE QRTAIFQKAQ FEQQEEENRL IPGRTRVTIP SSVITTEDGE
SGKQVVRYTI EVSQVDEDQK VVLGWVVARR YNEFYELDKA LKEWALDKSE DLALLDDMKN
KVVEIPGKRL VPNTSASFVE SRRAGLERYL QSLLASHVIC DSTILRSFLS RSSVPLQAGS
SDYLTSSTAS LANLAPHNIV KSLYKTMATS LDDASLGPSM LDMMYTTLSR QLNDFGGLVG
LGGEELVGLL PSALTGGPYT PQWLRHDPIA SPANPSKQRI GPMGGESGMT SFTGPICDLF
IEVFDLKENN WLRRQAIVVI LQQFLGSTIE SRKVRDSFRA AISSESLEKI VSSLEETLFP
GGERRPPSVA RMESEKLATR IRASKKLGLL IPDIAANMIG RSNARRAARR VFGALQDTRL
NQHLILSIMD EVLNAMFPSS P
//
