ID   A0A1A6C1K0_9GAMM        Unreviewed;       495 AA.
AC   A0A1A6C1K0;
DT   05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2016, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   RecName: Full=PDZ domain-containing protein {ECO:0000259|PROSITE:PS50106};
GN   ORFNames=Thpro_022696 {ECO:0000313|EMBL:OBS08446.1};
OS   Acidihalobacter prosperus.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Chromatiales;
OC   Ectothiorhodospiraceae; Acidihalobacter.
OX   NCBI_TaxID=160660 {ECO:0000313|EMBL:OBS08446.1, ECO:0000313|Proteomes:UP000029273};
RN   [1] {ECO:0000313|EMBL:OBS08446.1, ECO:0000313|Proteomes:UP000029273}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 5130 {ECO:0000313|EMBL:OBS08446.1,
RC   ECO:0000313|Proteomes:UP000029273};
RX   PubMed=25342676;
RA   Ossandon F.J., Cardenas J.P., Corbett M., Quatrini R., Holmes D.S.,
RA   Watkin E.;
RT   "Draft Genome Sequence of the Iron-Oxidizing, Acidophilic, and Halotolerant
RT   'Thiobacillus prosperus' Type Strain DSM 5130.";
RL   Genome Announc. 2:0-0(2014).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OBS08446.1}.
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DR   EMBL; JQSG02000006; OBS08446.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1A6C1K0; -.
DR   STRING; 160660.BJI67_03405; -.
DR   Proteomes; UP000029273; Unassembled WGS sequence.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   CDD; cd00987; PDZ_serine_protease; 2.
DR   Gene3D; 2.30.42.10; -; 2.
DR   Gene3D; 2.40.10.120; -; 1.
DR   InterPro; IPR001478; PDZ.
DR   InterPro; IPR036034; PDZ_sf.
DR   InterPro; IPR011782; Pept_S1C_Do.
DR   InterPro; IPR009003; Peptidase_S1_PA.
DR   InterPro; IPR001940; Peptidase_S1C.
DR   NCBIfam; TIGR02037; degP_htrA_DO; 1.
DR   PANTHER; PTHR22939; SERINE PROTEASE FAMILY S1C HTRA-RELATED; 1.
DR   PANTHER; PTHR22939:SF129; SERINE PROTEASE HTRA2, MITOCHONDRIAL; 1.
DR   Pfam; PF13180; PDZ_2; 1.
DR   Pfam; PF13365; Trypsin_2; 1.
DR   PRINTS; PR00834; PROTEASES2C.
DR   SMART; SM00228; PDZ; 2.
DR   SUPFAM; SSF50156; PDZ domain-like; 2.
DR   SUPFAM; SSF50494; Trypsin-like serine proteases; 1.
DR   PROSITE; PS50106; PDZ; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Protease {ECO:0000256|ARBA:ARBA00022670};
KW   Reference proteome {ECO:0000313|Proteomes:UP000029273};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Signal {ECO:0000256|ARBA:ARBA00022729}.
FT   DOMAIN          292..347
FT                   /note="PDZ"
FT                   /evidence="ECO:0000259|PROSITE:PS50106"
FT   ACT_SITE        135
FT                   /note="Charge relay system"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR611782-1"
FT   ACT_SITE        165
FT                   /note="Charge relay system"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR611782-1"
FT   ACT_SITE        239
FT                   /note="Charge relay system"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR611782-1"
SQ   SEQUENCE   495 AA;  52527 MW;  59113FCC31EA4ABE CRC64;
     MKWKMLPRRR HRAPRIWLNA FLAAVFGIGM GMSGWAFAGK PDLPIHPDTS PQRQLVNLPD
     FTPIIKRVGD AVVNISSTSS RVVHEGPQDP FPPGSPFHQF FRQFMAPGGQ QHEKVTDLGS
     GFILSSNGYI VTAGHVVRHA SHIVVTLTNH RSYPAKLVGL SVRYDTALLK IDAHDLPTAP
     IGNSNNLKVG QWLLAVGAPF GFFNTVTQGV VSAINRTLPH DDEYIPFIQS DVPINPGNSG
     GPLLNMSGQV VGINDQIYTS SGGYMGLSFS IPIDTVMHVV DDFKQHKPVQ FGWLGVEVQD
     VTTQMAKALN LKEPVGALVA SVSHHSPAAM AGLKPGDVIV TFNGQPVDTV GQLPPMVGNT
     LPGTKVDIGI LRNGKAMTLH ATVGVLPQNA GGGNGSTVNG NISRLHIQVQ SLSEKDKKHF
     GVGHGVLVIG VGNGPAANAG ITPGMVILDL AGEPIRSPEQ LKRLVDGLPA GHSIAVRVKA
     HGQTLFTAIT LPPAD
//