ID   A0A1A6C2H9_9GAMM        Unreviewed;       498 AA.
AC   A0A1A6C2H9;
DT   02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT   02-NOV-2016, sequence version 1.
DT   27-MAR-2024, entry version 13.
DE   SubName: Full=Glutamate synthase {ECO:0000313|EMBL:OBS08771.1};
GN   ORFNames=Thpro_023021 {ECO:0000313|EMBL:OBS08771.1};
OS   Acidihalobacter prosperus.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Chromatiales;
OC   Ectothiorhodospiraceae; Acidihalobacter.
OX   NCBI_TaxID=160660 {ECO:0000313|EMBL:OBS08771.1, ECO:0000313|Proteomes:UP000029273};
RN   [1] {ECO:0000313|EMBL:OBS08771.1, ECO:0000313|Proteomes:UP000029273}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 5130 {ECO:0000313|EMBL:OBS08771.1,
RC   ECO:0000313|Proteomes:UP000029273};
RX   PubMed=25342676;
RA   Ossandon F.J., Cardenas J.P., Corbett M., Quatrini R., Holmes D.S.,
RA   Watkin E.;
RT   "Draft Genome Sequence of the Iron-Oxidizing, Acidophilic, and Halotolerant
RT   'Thiobacillus prosperus' Type Strain DSM 5130.";
RL   Genome Announc. 2:0-0(2014).
CC   -!- SIMILARITY: Belongs to the glutamate synthase family.
CC       {ECO:0000256|ARBA:ARBA00009716, ECO:0000256|PIRNR:PIRNR006429}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OBS08771.1}.
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DR   EMBL; JQSG02000006; OBS08771.1; -; Genomic_DNA.
DR   RefSeq; WP_038091210.1; NZ_JQSG02000006.1.
DR   AlphaFoldDB; A0A1A6C2H9; -.
DR   OrthoDB; 9758182at2; -.
DR   Proteomes; UP000029273; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0015930; F:glutamate synthase activity; IEA:InterPro.
DR   GO; GO:0006537; P:glutamate biosynthetic process; IEA:InterPro.
DR   CDD; cd02808; GltS_FMN; 1.
DR   Gene3D; 3.20.20.70; Aldolase class I; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR024188; GltB.
DR   InterPro; IPR002932; Glu_synthdom.
DR   PANTHER; PTHR43819:SF1; ARCHAEAL GLUTAMATE SYNTHASE [NADPH]; 1.
DR   PANTHER; PTHR43819; ARCHAEAL-TYPE GLUTAMATE SYNTHASE [NADPH]; 1.
DR   Pfam; PF01645; Glu_synthase; 1.
DR   PIRSF; PIRSF006429; GOGAT_lg_2; 1.
DR   SUPFAM; SSF51395; FMN-linked oxidoreductases; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000029273};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        6..28
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          138..457
FT                   /note="Glutamate synthase"
FT                   /evidence="ECO:0000259|Pfam:PF01645"
SQ   SEQUENCE   498 AA;  54362 MW;  DB03B3EAE9E33772 CRC64;
     MELVWGLAVI FIFALGLLMV TAVVLYVLDV TQTTHAIRRN YPLIGRFRGL FETLGTFFRQ
     YFFAMDREEM PFNRAQRAWV YRAAKALNTN QSFGSTRDLR PSGTLLFVNC PFPMLERDIA
     VPGPVTIGPG CAEPYVTASL FNISGMSYGA ISRPAIQALA AGAREAGCWL NTGEGGLAPE
     HLAGGCDLVF QIGTAKYGVR EADGSLSDER LRAVAAHPQV RMFELKLSQG AKPGKGGILP
     GSKVTPEVAR IRGIPVGLDS ISPNRFPEID SEEDLLDLIA HVREVTGKPV GFKCVLGAYG
     WLDDLFALIC RRGAASAPDF ITLDSAEGGT GSAPVSLMDY MGLPLRESLP RLIDKLHEYG
     LHERIRVIAS GKLVNPADVA WALCVGADFV TSARGFMFAL GCIQSLRCHT NHCPTGITTH
     DPRLQKGLDP TLKAERVAHY AREIVREVGI IAHSCGVRQP RQLGRMHCRV VGEDGRSLSL
     DELYPIPETR TEYLRAVR
//