ID A0A1A6C3J1_9GAMM Unreviewed; 166 AA.
AC A0A1A6C3J1;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 24-JAN-2024, entry version 15.
DE RecName: Full=Lipopolysaccharide export system protein LptA {ECO:0000256|HAMAP-Rule:MF_01914};
DE Flags: Precursor;
GN Name=lptA {ECO:0000256|HAMAP-Rule:MF_01914};
GN ORFNames=Thpro_021438 {ECO:0000313|EMBL:OBS09110.1};
OS Acidihalobacter prosperus.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Chromatiales;
OC Ectothiorhodospiraceae; Acidihalobacter.
OX NCBI_TaxID=160660 {ECO:0000313|EMBL:OBS09110.1, ECO:0000313|Proteomes:UP000029273};
RN [1] {ECO:0000313|EMBL:OBS09110.1, ECO:0000313|Proteomes:UP000029273}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 5130 {ECO:0000313|EMBL:OBS09110.1,
RC ECO:0000313|Proteomes:UP000029273};
RX PubMed=25342676;
RA Ossandon F.J., Cardenas J.P., Corbett M., Quatrini R., Holmes D.S.,
RA Watkin E.;
RT "Draft Genome Sequence of the Iron-Oxidizing, Acidophilic, and Halotolerant
RT 'Thiobacillus prosperus' Type Strain DSM 5130.";
RL Genome Announc. 2:0-0(2014).
CC -!- FUNCTION: Involved in the assembly of lipopolysaccharide (LPS).
CC Required for the translocation of LPS from the inner membrane to the
CC outer membrane. May form a bridge between the inner membrane and the
CC outer membrane, via interactions with LptC and LptD, thereby
CC facilitating LPS transfer across the periplasm. {ECO:0000256|HAMAP-
CC Rule:MF_01914}.
CC -!- SUBUNIT: Component of the lipopolysaccharide transport and assembly
CC complex. {ECO:0000256|HAMAP-Rule:MF_01914}.
CC -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000256|HAMAP-Rule:MF_01914}.
CC -!- SIMILARITY: Belongs to the LptA family. {ECO:0000256|HAMAP-
CC Rule:MF_01914}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OBS09110.1}.
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DR EMBL; JQSG02000003; OBS09110.1; -; Genomic_DNA.
DR RefSeq; WP_052064240.1; NZ_JQSG02000003.1.
DR AlphaFoldDB; A0A1A6C3J1; -.
DR OrthoDB; 9795964at2; -.
DR Proteomes; UP000029273; Unassembled WGS sequence.
DR GO; GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
DR GO; GO:0001530; F:lipopolysaccharide binding; IEA:InterPro.
DR GO; GO:0043165; P:Gram-negative-bacterium-type cell outer membrane assembly; IEA:UniProtKB-UniRule.
DR GO; GO:0015920; P:lipopolysaccharide transport; IEA:UniProtKB-UniRule.
DR Gene3D; 2.60.450.10; Lipopolysaccharide (LPS) transport protein A like domain; 1.
DR HAMAP; MF_01914; LPS_assembly_LptA; 1.
DR InterPro; IPR014340; LptA.
DR InterPro; IPR005653; OstA-like_N.
DR NCBIfam; TIGR03002; outer_YhbN_LptA; 1.
DR PANTHER; PTHR36504; LIPOPOLYSACCHARIDE EXPORT SYSTEM PROTEIN LPTA; 1.
DR PANTHER; PTHR36504:SF1; LIPOPOLYSACCHARIDE EXPORT SYSTEM PROTEIN LPTA; 1.
DR Pfam; PF03968; LptD_N; 1.
PE 3: Inferred from homology;
KW Periplasm {ECO:0000256|ARBA:ARBA00022764, ECO:0000256|HAMAP-Rule:MF_01914};
KW Reference proteome {ECO:0000313|Proteomes:UP000029273};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|HAMAP-Rule:MF_01914};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|HAMAP-Rule:MF_01914}.
FT SIGNAL 1..18
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01914"
FT CHAIN 19..166
FT /note="Lipopolysaccharide export system protein LptA"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01914"
FT /id="PRO_5009002883"
FT DOMAIN 29..139
FT /note="Organic solvent tolerance-like N-terminal"
FT /evidence="ECO:0000259|Pfam:PF03968"
SQ SEQUENCE 166 AA; 17691 MW; FF8ED0519DD0B18E CRC64;
MPWRLLFLAA LLPAAAVAAP PVARDAPVHI SADRFHFDQK TGVGIYTGHV RVTQNTLTID
GDRLTVVAPP KGPVERLTMD GNPATFSDVT PKGKPVKGHA AHMLYLPDSR QIQLQGQAEL
SQERNTFSST HIVYDTKNGV VTAGAPGHRV EATLVPDQGT TGKSAP
//
