ID A0A1A6GID0_NEOLE Unreviewed; 1216 AA.
AC A0A1A6GID0;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 24-JAN-2024, entry version 27.
DE RecName: Full=Condensin complex subunit 1 {ECO:0000256|PIRNR:PIRNR017127};
GN ORFNames=A6R68_06386 {ECO:0000313|EMBL:OBS65067.1};
OS Neotoma lepida (Desert woodrat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea;
OC Cricetidae; Neotominae; Neotoma.
OX NCBI_TaxID=56216 {ECO:0000313|EMBL:OBS65067.1, ECO:0000313|Proteomes:UP000092124};
RN [1] {ECO:0000313|EMBL:OBS65067.1, ECO:0000313|Proteomes:UP000092124}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=417 {ECO:0000313|EMBL:OBS65067.1};
RC TISSUE=Liver {ECO:0000313|EMBL:OBS65067.1};
RA Campbell M., Oakeson K.F., Yandell M., Halpert J.R., Dearing D.;
RT "The Draft Genome Sequence and Annotation of the Desert Woodrat Neotoma
RT lepida.";
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Regulatory subunit of the condensin complex, a complex
CC required for conversion of interphase chromatin into mitotic-like
CC condense chromosomes. The condensin complex probably introduces
CC positive supercoils into relaxed DNA in the presence of type I
CC topoisomerases and converts nicked DNA into positive knotted forms in
CC the presence of type II topoisomerases.
CC {ECO:0000256|PIRNR:PIRNR017127}.
CC -!- SUBCELLULAR LOCATION: Chromosome {ECO:0000256|ARBA:ARBA00004286}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the CND1 (condensin subunit 1) family.
CC {ECO:0000256|ARBA:ARBA00009606, ECO:0000256|PIRNR:PIRNR017127}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OBS65067.1}.
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DR EMBL; LZPO01097109; OBS65067.1; -; Genomic_DNA.
DR STRING; 56216.A0A1A6GID0; -.
DR Proteomes; UP000092124; Unassembled WGS sequence.
DR GO; GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR GO; GO:0007076; P:mitotic chromosome condensation; IEA:InterPro.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR026971; CND1/NCAPD3.
DR InterPro; IPR032682; Cnd1_C.
DR InterPro; IPR007673; Condensin_cplx_su1.
DR InterPro; IPR024324; Condensin_cplx_su1_N.
DR PANTHER; PTHR14222; CONDENSIN; 1.
DR PANTHER; PTHR14222:SF2; CONDENSIN COMPLEX SUBUNIT 1; 1.
DR Pfam; PF12717; Cnd1; 1.
DR Pfam; PF12922; Cnd1_N; 1.
DR PIRSF; PIRSF017127; Condensin_D2; 3.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000256|ARBA:ARBA00023306, ECO:0000256|PIRNR:PIRNR017127};
KW Cell division {ECO:0000256|ARBA:ARBA00022618,
KW ECO:0000256|PIRNR:PIRNR017127}; Chromosome {ECO:0000256|ARBA:ARBA00022454};
KW DNA condensation {ECO:0000256|ARBA:ARBA00023067,
KW ECO:0000256|PIRNR:PIRNR017127};
KW Mitosis {ECO:0000256|ARBA:ARBA00022776, ECO:0000256|PIRNR:PIRNR017127};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000092124}.
FT DOMAIN 16..124
FT /note="Condensin complex subunit 1 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF12922"
FT DOMAIN 885..1046
FT /note="Condensin complex subunit 1 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF12717"
FT REGION 407..436
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1111..1216
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 407..433
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1123..1151
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1216 AA; 135898 MW; 4729DD3FCCFA60D0 CRC64;
MKKVNETNSQ ILPLTVVSCH SQELPSILDD VTLSVSDRSA HLNALKMNCY ALIRLLESFE
NVTSRTSLID LDVGGKGKKA RAKAALGFDW EETRQPVLQL LTQLLQLDIR HLWNHSVIEE
EFVRWVKIAA NDRATVKIIQ MLQHFEHLPS VLVAAVSLWA TDYGMKSIVG EINYMMRNAV
LAAVAEMVLQ VLKGDQLEEA ARETRDQFLD ILQAHGHDVN SFVRSRVLQL FTRIVQQKAV
VALAVGRLAD KSVLVCKNAI QLLASFLANN PFSCKLSDTD LAGPLQKEIQ KLQEMRAQRR
TAAASAALDP EEEWEAMLPE LKSTLQQLLQ LPQEGADQQI ADTETAEEVK GRIRQLLAKA
SYKQAIILTR EATSHFQESE PFSHTELEEN SLLTLLGIIF KGPAASTQGS PGDTVSGLMD
SKESPSVSEP EGSQRNDELV KQEMLVQYLQ DAYSFSQKVT EAIGVISKMM YENTTTVVQE
VIEFFVMVFQ FGVPQALFGV RRMLPLIWSK EPGVREAVLN AYRQLYLSPK GDSARATAQA
LIQNLSLLLV DASVGTIQCL EEILCEFVQK DEIKPAVTQL LWERATEKVP CSPLERCSSV
MLLGMMARGK PEIVGSNLDT LVSVGLDEKF PQDYRLAQQV CLAIANISDR RKPSLGERQP
PFRLPQEHKL FERLREMVTK GFAHPDPLWI PFKEVAVTLT YQLAEGPEVI CAQMLQGCAK
QALEKLEKNT PEEDPKETVP RLPTFLLMNL LSLAGDVALQ QLVHLEQAVS GELGRRRVLR
EEQEHRTKEP KEKEELGLVG ATADDTEAEL IRGICEKELL DGNQVLAAFV PLLLKVCNNP
GLYGNPDLCA AASLALGKFC MISATFCDSQ LRLLFTMLEK SSLPTVRSNL MVATGDLAIR
FPNLVDPWTP HLYARLRDPA QQVRRTAGLV MTHLILKDMV KVKGQVSEMA VLLIDPVPQI
AALAKNFFNE LSHKGNAIYN LLPDIISRLS DPEGGVEEEP FHTIMKQLLS YITKDKQTES
LVEKLCQRFR TARTERQYRD LAYCVSQLPL TERGLHKMLD NFDCFGDKLL DESVFNAFLS
VVGKLRRGAK PEGKAVIDEF EQKLRACHTR GMDGIEEVET GQGGSQRALS AKKPSAVSRK
QPLTSVDSDN DFVTPKPRRT NPRRPNTQQP KSKKKAKVVF SXDEASEDEL SAEMTEEETP
KRTTPIRRAS ARRHRS
//
