ID A0A1A6GJK1_NEOLE Unreviewed; 359 AA.
AC A0A1A6GJK1;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 27-MAR-2024, entry version 15.
DE RecName: Full=Ig-like domain-containing protein {ECO:0000259|PROSITE:PS50835};
DE Flags: Fragment;
GN ORFNames=A6R68_05410 {ECO:0000313|EMBL:OBS66049.1};
OS Neotoma lepida (Desert woodrat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea;
OC Cricetidae; Neotominae; Neotoma.
OX NCBI_TaxID=56216 {ECO:0000313|EMBL:OBS66049.1, ECO:0000313|Proteomes:UP000092124};
RN [1] {ECO:0000313|EMBL:OBS66049.1, ECO:0000313|Proteomes:UP000092124}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=417 {ECO:0000313|EMBL:OBS66049.1};
RC TISSUE=Liver {ECO:0000313|EMBL:OBS66049.1};
RA Campbell M., Oakeson K.F., Yandell M., Halpert J.R., Dearing D.;
RT "The Draft Genome Sequence and Annotation of the Desert Woodrat Neotoma
RT lepida.";
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBUNIT: Alpha-beta TR is a heterodimer composed of an alpha and beta
CC chain; disulfide-linked. The alpha-beta TR is associated with the
CC transmembrane signaling CD3 coreceptor proteins to form the TR-CD3 (TcR
CC or TCR). The assembly of alpha-beta TR heterodimers with CD3 occurs in
CC the endoplasmic reticulum where a single alpha-beta TR heterodimer
CC associates with one CD3D-CD3E heterodimer, one CD3G-CD3E heterodimer
CC and one CD247 homodimer forming a stable octameric structure. CD3D-CD3E
CC and CD3G-CD3E heterodimers preferentially associate with TR alpha and
CC TR beta chains, respectively. The association of the CD247 homodimer is
CC the last step of TcR assembly in the endoplasmic reticulum and is
CC required for transport to the cell surface.
CC {ECO:0000256|ARBA:ARBA00038651}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OBS66049.1}.
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DR EMBL; LZPO01087602; OBS66049.1; -; Genomic_DNA.
DR STRING; 56216.A0A1A6GJK1; -.
DR Proteomes; UP000092124; Unassembled WGS sequence.
DR Gene3D; 2.60.40.10; Immunoglobulins; 3.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR InterPro; IPR013106; Ig_V-set.
DR PANTHER; PTHR19343:SF13; IG-LIKE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR19343; T CELL RECEPTOR ALPHA VARIABLE 1-2; 1.
DR Pfam; PF07686; V-set; 3.
DR SMART; SM00409; IG; 3.
DR SMART; SM00408; IGc2; 2.
DR SMART; SM00406; IGv; 3.
DR SUPFAM; SSF48726; Immunoglobulin; 3.
DR PROSITE; PS50835; IG_LIKE; 3.
PE 4: Predicted;
KW Adaptive immunity {ECO:0000256|ARBA:ARBA00043266};
KW Immunity {ECO:0000256|ARBA:ARBA00043266};
KW Reference proteome {ECO:0000313|Proteomes:UP000092124};
KW T cell receptor {ECO:0000256|ARBA:ARBA00043266}.
FT DOMAIN 5..96
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 132..241
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 242..336
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:OBS66049.1"
FT NON_TER 359
FT /evidence="ECO:0000313|EMBL:OBS66049.1"
SQ SEQUENCE 359 AA; 39317 MW; 2114CCBC903FF278 CRC64;
ESHGEQLKQQ PSTLNVGEGD XAIINCTYTG SAFSXFPWYK QEAGKSPQLV IDILENVDRK
QNQRLTVLLD KKAKHFSLHI TATQPGDSAI YFCAASTHWF PGTCSLFSNL LWGLDPIHIL
CLVMTVKMNS SPGFVTVILL ILGRTHGNSV TQTGGQVTIS EGGFLTINCT YSITTIAYPA
LFWYVRYPGE SLQLLLKVST AGAKGSSRGF EATYDKESTS FHLQKASVQE SDSAVYYCAL
SDTVTETAGE LSINSERQQG ESCVLHCSYT VSPANNLRWY RQDTGRGLVS LAVMTHTENK
KSNGRYSATL DTDAQHSTLH ITASQLEDTA SYICVVGAPC STDACTQYQN LLLEASRRH
//
