ID   A0A1A6GL65_NEOLE        Unreviewed;       246 AA.
AC   A0A1A6GL65;
DT   05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2016, sequence version 1.
DT   27-MAR-2024, entry version 18.
DE   RecName: Full=Threonyl/alanyl tRNA synthetase SAD domain-containing protein {ECO:0000259|SMART:SM00863};
GN   ORFNames=A6R68_04540 {ECO:0000313|EMBL:OBS66951.1};
OS   Neotoma lepida (Desert woodrat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea;
OC   Cricetidae; Neotominae; Neotoma.
OX   NCBI_TaxID=56216 {ECO:0000313|EMBL:OBS66951.1, ECO:0000313|Proteomes:UP000092124};
RN   [1] {ECO:0000313|EMBL:OBS66951.1, ECO:0000313|Proteomes:UP000092124}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=417 {ECO:0000313|EMBL:OBS66951.1};
RC   TISSUE=Liver {ECO:0000313|EMBL:OBS66951.1};
RA   Campbell M., Oakeson K.F., Yandell M., Halpert J.R., Dearing D.;
RT   "The Draft Genome Sequence and Annotation of the Desert Woodrat Neotoma
RT   lepida.";
RL   Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|ARBA:ARBA00001947};
CC   -!- SIMILARITY: Belongs to the class-II aminoacyl-tRNA synthetase family.
CC       Alax-L subfamily. {ECO:0000256|ARBA:ARBA00008429}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OBS66951.1}.
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DR   EMBL; LZPO01087168; OBS66951.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1A6GL65; -.
DR   STRING; 56216.A0A1A6GL65; -.
DR   Proteomes; UP000092124; Unassembled WGS sequence.
DR   GO; GO:0002161; F:aminoacyl-tRNA editing activity; IEA:UniProt.
DR   GO; GO:0004812; F:aminoacyl-tRNA ligase activity; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0043039; P:tRNA aminoacylation; IEA:InterPro.
DR   InterPro; IPR018163; Thr/Ala-tRNA-synth_IIc_edit.
DR   InterPro; IPR009000; Transl_B-barrel_sf.
DR   InterPro; IPR012947; tRNA_SAD.
DR   PANTHER; PTHR43462; ALANYL-TRNA EDITING PROTEIN; 1.
DR   PANTHER; PTHR43462:SF1; ALANYL-TRNA EDITING PROTEIN AARSD1; 1.
DR   Pfam; PF07973; tRNA_SAD; 1.
DR   SMART; SM00863; tRNA_SAD; 1.
DR   SUPFAM; SSF55186; ThrRS/AlaRS common domain; 1.
DR   SUPFAM; SSF50447; Translation proteins; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000092124}.
FT   DOMAIN          71..114
FT                   /note="Threonyl/alanyl tRNA synthetase SAD"
FT                   /evidence="ECO:0000259|SMART:SM00863"
SQ   SEQUENCE   246 AA;  26661 MW;  D4C928A9796CACE4 CRC64;
     MAFLCQRDSY ARELTTTVVS CSPAELQTDA SGGKKEVLSG FQVVLEDTLL FPEGGGQVRG
     RGLPDDHAGP IRVVTIKGVD SNMCCGTHVS NLSDLQVIKI LGTEKGKKNK SNLIFLAGNR
     VLKWMERSHG SEKALTTLLK YAPLPPLLPR PAPLGLGILP ARGIQVVEEQ SGWQKQQWQE
     TLLFLTVGDE KAVSLTTSPF SRVAEVLEGK GAGKKGRFQG KATKMSRRAE VQALLQDYVS
     TQSAEE
//