ID A0A1A6GN31_NEOLE Unreviewed; 521 AA.
AC A0A1A6GN31;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=Interleukin-13 receptor subunit alpha-1 {ECO:0008006|Google:ProtNLM};
DE Flags: Fragment;
GN ORFNames=A6R68_04339 {ECO:0000313|EMBL:OBS67125.1};
OS Neotoma lepida (Desert woodrat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea;
OC Cricetidae; Neotominae; Neotoma.
OX NCBI_TaxID=56216 {ECO:0000313|EMBL:OBS67125.1, ECO:0000313|Proteomes:UP000092124};
RN [1] {ECO:0000313|EMBL:OBS67125.1, ECO:0000313|Proteomes:UP000092124}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=417 {ECO:0000313|EMBL:OBS67125.1};
RC TISSUE=Liver {ECO:0000313|EMBL:OBS67125.1};
RA Campbell M., Oakeson K.F., Yandell M., Halpert J.R., Dearing D.;
RT "The Draft Genome Sequence and Annotation of the Desert Woodrat Neotoma
RT lepida.";
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OBS67125.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; LZPO01087149; OBS67125.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1A6GN31; -.
DR STRING; 56216.A0A1A6GN31; -.
DR Proteomes; UP000092124; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004896; F:cytokine receptor activity; IEA:InterPro.
DR Gene3D; 2.60.40.10; Immunoglobulins; 3.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR040566; Il13Ra_Ig.
DR InterPro; IPR003532; Short_hematopoietin_rcpt_2_CS.
DR InterPro; IPR015321; TypeI_recpt_CBD.
DR PANTHER; PTHR23037; CYTOKINE RECEPTOR; 1.
DR PANTHER; PTHR23037:SF28; ERYTHROPOIETIN RECEPTOR; 1.
DR Pfam; PF18001; Il13Ra_Ig; 1.
DR Pfam; PF09240; IL6Ra-bind; 1.
DR SUPFAM; SSF49265; Fibronectin type III; 2.
DR PROSITE; PS01356; HEMATOPO_REC_S_F2; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000092124};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 330..353
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 19..112
FT /note="Interleukin-13 receptor subunit alpha-1 Ig-like"
FT /evidence="ECO:0000259|Pfam:PF18001"
FT DOMAIN 118..209
FT /note="Type I cytokine receptor cytokine-binding"
FT /evidence="ECO:0000259|Pfam:PF09240"
FT NON_TER 521
FT /evidence="ECO:0000313|EMBL:OBS67125.1"
SQ SEQUENCE 521 AA; 58638 MW; 2D8C0068F5995B70 CRC64;
MIHTSSFACE GVATKSEAQP PVTNLSVSVE NLCTITWTWS PPEGANPNCS LRYLSHFDDK
QDKKIAPETR RSKEVPLNEK ICLQVASQCS ANESEKPSAL MTKCISPPEG DPESAATELQ
CIWHNLSYMK CSWLPGRNAS PDTNYTLYYW YSSLGKILQC ENIYREGQRI GCSFKLTKED
SSFEQQSIQI MVKDNAGKIR PSFKIVSLTS YVKPGPPHIK HLFLKNDALF VQWKNPQNFF
SRCLSSEVEV NSSQTQLHSP FSVEEDKCQN SGSERNTEGT SCFILPGVLP ETVYTVRVRV
KTNRLCFDDN HLWSNWSEAQ SIGEEPNSTF YITMLLIIPV IVAGAIIVLL LYLKRLKIII
FPPIPDPGKI FKEMFGDQND DTLHWKKYDI HEKQSKEETD SVVLIENLKK IAIARLLNFP
SPMLIPCYAY SPILFHVGTK RNLASVVVVV VEEHCALAFQ EMGVHGVIDA QGSHKHPYDE
KCPSVLSFFG GLMMPVSGEL LKSLRRDNGW KNPASECKGS Q
//
