ID   A0A1A6GQN8_NEOLE        Unreviewed;       163 AA.
AC   A0A1A6GQN8;
DT   05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2016, sequence version 1.
DT   24-JAN-2024, entry version 19.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:OBS68496.1};
GN   ORFNames=A6R68_02958 {ECO:0000313|EMBL:OBS68496.1};
OS   Neotoma lepida (Desert woodrat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea;
OC   Cricetidae; Neotominae; Neotoma.
OX   NCBI_TaxID=56216 {ECO:0000313|EMBL:OBS68496.1, ECO:0000313|Proteomes:UP000092124};
RN   [1] {ECO:0000313|EMBL:OBS68496.1, ECO:0000313|Proteomes:UP000092124}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=417 {ECO:0000313|EMBL:OBS68496.1};
RC   TISSUE=Liver {ECO:0000313|EMBL:OBS68496.1};
RA   Campbell M., Oakeson K.F., Yandell M., Halpert J.R., Dearing D.;
RT   "The Draft Genome Sequence and Annotation of the Desert Woodrat Neotoma
RT   lepida.";
RL   Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Extremely potent competitive inhibitor of cAMP-dependent
CC       protein kinase activity, this protein interacts with the catalytic
CC       subunit of the enzyme after the cAMP-induced dissociation of its
CC       regulatory chains. {ECO:0000256|ARBA:ARBA00002844}.
CC   -!- SIMILARITY: Belongs to the PKI family. {ECO:0000256|ARBA:ARBA00006393}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OBS68496.1}.
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DR   EMBL; LZPO01075910; OBS68496.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1A6GQN8; -.
DR   STRING; 56216.A0A1A6GQN8; -.
DR   Proteomes; UP000092124; Unassembled WGS sequence.
DR   GO; GO:0004862; F:cAMP-dependent protein kinase inhibitor activity; IEA:InterPro.
DR   InterPro; IPR004171; cAMP_dep_PKI.
DR   PANTHER; PTHR15416:SF5; CAMP-DEPENDENT PROTEIN KINASE INHIBITOR GAMMA; 1.
DR   PANTHER; PTHR15416; CAMP-DEPENDENT PROTEIN KINASE INHIBITOR/PKI; 1.
DR   Pfam; PF02827; PKI; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000092124}.
FT   REGION          34..53
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          82..119
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          140..163
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        91..118
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        148..163
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   163 AA;  17540 MW;  B1D05F9EFC9596F0 CRC64;
     MAPRFCFHIK CLPSPGHRLS EDYNTPDPSY CQMATRPPTG LELSPAQSQG GLTSQPQFQY
     LERDDDHEDL LVFIRQDVFD EGPASADESD GTMKAESSYS DFISCDRTDS QNAVPDIQGD
     SEAVSVQKLA GDMGKLALAG AEGQASGSTL DKEGSSQPES SEN
//