ID   A0A1A6GT00_NEOLE        Unreviewed;       686 AA.
AC   A0A1A6GT00;
DT   05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2016, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   RecName: Full=PID domain-containing protein {ECO:0000259|SMART:SM00462};
GN   ORFNames=A6R68_02667 {ECO:0000313|EMBL:OBS68790.1};
OS   Neotoma lepida (Desert woodrat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea;
OC   Cricetidae; Neotominae; Neotoma.
OX   NCBI_TaxID=56216 {ECO:0000313|EMBL:OBS68790.1, ECO:0000313|Proteomes:UP000092124};
RN   [1] {ECO:0000313|EMBL:OBS68790.1, ECO:0000313|Proteomes:UP000092124}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=417 {ECO:0000313|EMBL:OBS68790.1};
RC   TISSUE=Liver {ECO:0000313|EMBL:OBS68790.1};
RA   Campbell M., Oakeson K.F., Yandell M., Halpert J.R., Dearing D.;
RT   "The Draft Genome Sequence and Annotation of the Desert Woodrat Neotoma
RT   lepida.";
RL   Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OBS68790.1}.
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DR   EMBL; LZPO01075865; OBS68790.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1A6GT00; -.
DR   STRING; 56216.A0A1A6GT00; -.
DR   Proteomes; UP000092124; Unassembled WGS sequence.
DR   GO; GO:0001540; F:amyloid-beta binding; IEA:InterPro.
DR   CDD; cd01272; PTB1_Fe65; 1.
DR   Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR   InterPro; IPR039576; APBB1/2/3.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR006020; PTB/PI_dom.
DR   PANTHER; PTHR14058; AMYLOID BETA A4 PRECURSOR PROTEIN-BINDING FAMILY B; 1.
DR   PANTHER; PTHR14058:SF11; AMYLOID BETA PRECURSOR PROTEIN BINDING FAMILY B MEMBER 2; 1.
DR   Pfam; PF00640; PID; 1.
DR   SMART; SM00462; PTB; 1.
DR   SUPFAM; SSF50729; PH domain-like; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000092124}.
FT   DOMAIN          564..678
FT                   /note="PID"
FT                   /evidence="ECO:0000259|SMART:SM00462"
FT   REGION          346..447
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        382..397
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        421..445
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   686 AA;  75068 MW;  091FFDB710D4E4AE CRC64;
     MDDFNESGVG ISSVGAQLHR LACLLIPETP LDTPFAKSLS MFLAPFVRQL GDRLPHFTLG
     QSQNQDRYRP QSIRPVSVPF VQAFTASYCE VSYTHLDVYK RQTPEVKQVS GIAAGVGNAH
     QLGLHLLQLK GTREKQYLYI VTIANYNRFP TPLLTPRDPC QKYFQKLTWQ LMRADSGVDT
     LAVFMASSGT TDVANRNSPA TPPNTLNLRS SHNELLNAEI KHSDAKNSTP PKCRKKYALT
     NIQAAMGLSD PAVQPLLGNG SANIKLVKNG ENQLRKAAEQ GQQDPNKNIS PTAVINLTSE
     KLEVKDLHPP ESSGCEILPS QPRRTKSFLN YYADLETSAR ELGQNLGPCQ GVGEEKAQPG
     PGQAPVVIGN GDLLIQKPDR PQSSPEDGQV ATVSSSPETK KDHPKTGAKT DCALHRIQNL
     APSDEESSWT TLSQDSASPS SPDETGEDFS AAVHANLFFF GLWFRKETIS GVTIHFRRIR
     IYHLAGKESV TLPGPIIGTS QQERLSGNGL SPSQWTSRDL HAATVNPDPS LKEFEGATLR
     YASLKLRNAP HADDDDSCSV NSDPEAKCFA VRSLGWVEMA EEDLAPGKSS VAVNNCIRQL
     SYCKNDIRDT VGIWGEGKDM YLILENDMLS LVDPMDRSVL HSQPIVSIRV WGVGRDNGRV
     VAKAVSRSKI RQQGATYPVI IIGLLF
//