ID A0A1A6GXI8_NEOLE Unreviewed; 394 AA.
AC A0A1A6GXI8;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=IRF tryptophan pentad repeat domain-containing protein {ECO:0000259|PROSITE:PS51507};
GN ORFNames=A6R68_00545 {ECO:0000313|EMBL:OBS70876.1};
OS Neotoma lepida (Desert woodrat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea;
OC Cricetidae; Neotominae; Neotoma.
OX NCBI_TaxID=56216 {ECO:0000313|EMBL:OBS70876.1, ECO:0000313|Proteomes:UP000092124};
RN [1] {ECO:0000313|EMBL:OBS70876.1, ECO:0000313|Proteomes:UP000092124}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=417 {ECO:0000313|EMBL:OBS70876.1};
RC TISSUE=Liver {ECO:0000313|EMBL:OBS70876.1};
RA Campbell M., Oakeson K.F., Yandell M., Halpert J.R., Dearing D.;
RT "The Draft Genome Sequence and Annotation of the Desert Woodrat Neotoma
RT lepida.";
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OBS70876.1}.
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DR EMBL; LZPO01066266; OBS70876.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1A6GXI8; -.
DR STRING; 56216.A0A1A6GXI8; -.
DR Proteomes; UP000092124; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0000976; F:transcription cis-regulatory region binding; IEA:InterPro.
DR GO; GO:0045893; P:positive regulation of DNA-templated transcription; IEA:UniProt.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:UniProt.
DR CDD; cd00103; IRF; 1.
DR Gene3D; 2.60.200.10; -; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR019817; Interferon_reg_fac_CS.
DR InterPro; IPR001346; Interferon_reg_fact_DNA-bd_dom.
DR InterPro; IPR019471; Interferon_reg_factor-3.
DR InterPro; IPR017855; SMAD-like_dom_sf.
DR InterPro; IPR008984; SMAD_FHA_dom_sf.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR11949; INTERFERON REGULATORY FACTOR; 1.
DR PANTHER; PTHR11949:SF2; INTERFERON REGULATORY FACTOR 7; 1.
DR Pfam; PF00605; IRF; 1.
DR Pfam; PF10401; IRF-3; 1.
DR PRINTS; PR00267; INTFRNREGFCT.
DR SMART; SM00348; IRF; 1.
DR SMART; SM01243; IRF-3; 1.
DR SUPFAM; SSF49879; SMAD/FHA domain; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS00601; IRF_1; 1.
DR PROSITE; PS51507; IRF_2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000092124}.
FT DOMAIN 9..123
FT /note="IRF tryptophan pentad repeat"
FT /evidence="ECO:0000259|PROSITE:PS51507"
SQ SEQUENCE 394 AA; 44325 MW; 23D9280EF324F587 CRC64;
MATERGPQRM LFGEWLLGEV SSGQYEGLRW LDEAHTVFRV PWKHFGRRDL DEADARIFKA
WAVARGRWPP SGGNLPLPEA EAAERAGWKT NFRCALHSTG RFILRQDNSG DPADPHKVYE
LSLELGSTEG PAMENREDVA LSNALPTQAL QYSLLEDHLL EYESGANSVP SQDPERNLGF
LDVTIMYKGR TVLQAMVGHP SCVFLYSPMS SVINSEPQQV IFPSPAELPD QKQLHYTETL
LQHVSPGLQL ELRGPSLWAL RMGKCKVYWE VGSPMGSTNP STPAQLLERN CDTPIFDFST
FFRELEEFRA RRRQGSPHYT IYLGFGQDLS AGRPKEKSLI LVKLEPWLCK AYLEGVQREG
VSSLDSSSLG LCLSSTNSLY DDIEHFLMDM GQWA
//
