ID A0A1A6H1P0_NEOLE Unreviewed; 893 AA.
AC A0A1A6H1P0;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE RecName: Full=Transcription factor E2F7 {ECO:0000256|ARBA:ARBA00039675};
GN ORFNames=A6R68_13241 {ECO:0000313|EMBL:OBS72184.1};
OS Neotoma lepida (Desert woodrat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea;
OC Cricetidae; Neotominae; Neotoma.
OX NCBI_TaxID=56216 {ECO:0000313|EMBL:OBS72184.1, ECO:0000313|Proteomes:UP000092124};
RN [1] {ECO:0000313|EMBL:OBS72184.1, ECO:0000313|Proteomes:UP000092124}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=417 {ECO:0000313|EMBL:OBS72184.1};
RC TISSUE=Liver {ECO:0000313|EMBL:OBS72184.1};
RA Campbell M., Oakeson K.F., Yandell M., Halpert J.R., Dearing D.;
RT "The Draft Genome Sequence and Annotation of the Desert Woodrat Neotoma
RT lepida.";
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU003796}.
CC -!- SIMILARITY: Belongs to the E2F/DP family.
CC {ECO:0000256|ARBA:ARBA00010940, ECO:0000256|RuleBase:RU003796}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OBS72184.1}.
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DR EMBL; LZPO01055164; OBS72184.1; -; Genomic_DNA.
DR STRING; 56216.A0A1A6H1P0; -.
DR Proteomes; UP000092124; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005667; C:transcription regulator complex; IEA:InterPro.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 2.
DR InterPro; IPR015633; E2F.
DR InterPro; IPR003316; E2F_WHTH_DNA-bd_dom.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR12081; TRANSCRIPTION FACTOR E2F; 1.
DR PANTHER; PTHR12081:SF25; TRANSCRIPTION FACTOR E2F7; 1.
DR Pfam; PF02319; E2F_TDP; 2.
DR SMART; SM01372; E2F_TDP; 2.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
PE 3: Inferred from homology;
KW Activator {ECO:0000256|ARBA:ARBA00023159};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU003796};
KW Nucleus {ECO:0000256|RuleBase:RU003796};
KW Reference proteome {ECO:0000313|Proteomes:UP000092124};
KW Repressor {ECO:0000256|ARBA:ARBA00022491};
KW Transcription {ECO:0000256|ARBA:ARBA00023163,
KW ECO:0000256|RuleBase:RU003796};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015,
KW ECO:0000256|RuleBase:RU003796}.
FT DOMAIN 143..212
FT /note="E2F/DP family winged-helix DNA-binding"
FT /evidence="ECO:0000259|SMART:SM01372"
FT DOMAIN 283..359
FT /note="E2F/DP family winged-helix DNA-binding"
FT /evidence="ECO:0000259|SMART:SM01372"
FT REGION 253..282
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 499..519
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 550..635
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 788..893
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 578..596
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 598..623
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 788..809
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 878..893
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 893 AA; 97888 MW; D4BF4DDF692D0B9F CRC64;
MEVXCLTLKD LISPRQARLD FAVEDAENAQ KENIFVDRSK MTPKTPMKNE PMDLSKQRIF
TPERSPITPV KPVDRQPQME PWTPTANLKM LISAASPDIR DREKKKGXFR PIENXEDAFV
NSLQLDVVGD GTSDDYEKQR PSRKQKSLGL LCQKFLARYP SYPLSTEKTT ISLDEVAVSL
GVERRRIYDI VNVLESLHLV SRVAKNQYGW HGRHSLPKTL RTLQRLGEEQ KYQEQMACLQ
QKELDLVDYR FGERRKDGSP DPQDQHLLDF SESDYPSSSA NSRKDKSLRI MSQKFVMLFL
VSKTKIVTLD VAAKILIEES QDTPDHSKFK TNVLTSLALI KKVHVTEERG RKPAFKWIGP
VDFXAIDEEL LDVSASVLPE WKKETYGQIR VCAKQRLARH GSFNTVQTSE KILRKVSSEP
SSPQGGKQGS AYSLEIGSLA AIYRQKVEDN LQGEAFTSKR VVPPAGSLDP AHPADSEYRV
KPLAHPVFSV AQTDLQTFPA PNGLNGQVGG HLPSAASDGE SLKPALLAGQ PLVYVPSSLF
MLYGSLQEGL SPESRSEEDG GSEVPADLSL ASSAQKRLCE ERSPREEDEP AMKRQSQEFE
DSPLSLVXPK RPSNSTALAS PVTMGDGRST PLEDAGVKGQ LPAAEEVSGR AVANCCFMTS
ECGNLLRNPD AEKSSSENGX AKDSSLPQYL YVQSPAGLNG FNMLLPGSQT PHTVGPSSGQ
LPPFGVPCMF LPSPSLAPFP VLYSPTIPGP LSSAPGTLPN TGPMNFGLSP LGSTAHLLLS
PAAMVNPKSS SIPSTDPQLQ CQPSLNLSPG MPGSHGVVHP ESPGYMRHPV SMIKAEQSPA
PATPKSIHQR HRETFFKTPG SLGDPVFRKR ERNQSRNTSS XQRRLEISSS GPD
//
