ID A0A1A6H2Y0_NEOLE Unreviewed; 416 AA.
AC A0A1A6H2Y0;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 22-FEB-2023, entry version 18.
DE RecName: Full=Cytosol aminopeptidase domain-containing protein {ECO:0000259|PROSITE:PS00631};
GN ORFNames=A6R68_13259 {ECO:0000313|EMBL:OBS72165.1};
OS Neotoma lepida (Desert woodrat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea;
OC Cricetidae; Neotominae; Neotoma.
OX NCBI_TaxID=56216 {ECO:0000313|EMBL:OBS72165.1, ECO:0000313|Proteomes:UP000092124};
RN [1] {ECO:0000313|EMBL:OBS72165.1, ECO:0000313|Proteomes:UP000092124}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=417 {ECO:0000313|EMBL:OBS72165.1};
RC TISSUE=Liver {ECO:0000313|EMBL:OBS72165.1};
RA Campbell M., Oakeson K.F., Yandell M., Halpert J.R., Dearing D.;
RT "The Draft Genome Sequence and Annotation of the Desert Woodrat Neotoma
RT lepida.";
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase M17 family.
CC {ECO:0000256|ARBA:ARBA00009528}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OBS72165.1}.
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DR EMBL; LZPO01055173; OBS72165.1; -; Genomic_DNA.
DR STRING; 56216.A0A1A6H2Y0; -.
DR Proteomes; UP000092124; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0030145; F:manganese ion binding; IEA:InterPro.
DR GO; GO:0070006; F:metalloaminopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR Gene3D; 3.40.630.10; Zn peptidases; 1.
DR Gene3D; 3.40.50.10590; Zn-dependent exopeptidases; 1.
DR InterPro; IPR011356; Leucine_aapep/pepB.
DR InterPro; IPR041417; NPEPL1_N.
DR InterPro; IPR000819; Peptidase_M17_C.
DR PANTHER; PTHR11963:SF4; AMINOPEPTIDASE NPEPL1-RELATED; 1.
DR PANTHER; PTHR11963; LEUCINE AMINOPEPTIDASE-RELATED; 1.
DR Pfam; PF18295; Pdase_M17_N2; 1.
DR Pfam; PF00883; Peptidase_M17; 1.
DR PRINTS; PR00481; LAMNOPPTDASE.
DR SUPFAM; SSF53187; Zn-dependent exopeptidases; 1.
DR PROSITE; PS00631; CYTOSOL_AP; 1.
PE 3: Inferred from homology;
KW Aminopeptidase {ECO:0000256|ARBA:ARBA00022438};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Protease {ECO:0000256|ARBA:ARBA00022670};
KW Reference proteome {ECO:0000313|Proteomes:UP000092124}.
FT DOMAIN 328..335
FT /note="Cytosol aminopeptidase"
FT /evidence="ECO:0000259|PROSITE:PS00631"
SQ SEQUENCE 416 AA; 44525 MW; 7763B4CB5EA81E70 CRC64;
MASVGLQFQA SAGDADPQSR PLLLLGQLQH LHRVPWSHVR GKLQPRVTEE LWQAALATLN
PNPTDSCPLY LNCATVAALP SRVSRHNSPS AAHFITRLVR TCLPPGTHRC ILMVCEQPEV
FASACALARA FPLFTHRSGA SRRTEKRTVM VEFFLVGQDN GPVEVSTLQC LTNTTEGVRL
AARIVDTPCN EMNTDIFLEE ISQVGKELGI TPTIIRDEQL XARGFGGIYG VGKAALHPPA
LAILSHTPDG ATQTIAWVGK GITTMPGMKR DCGGAAAILG AFRAAIKQGF KDNLHAVFCL
AENAVGPNAT RPDDIHLLYS GKTVEINNTD AEGRLVLADG VSYACKDLGA DIIVDMATLT
GAQGERATGF GVALLLALFG RASEDPLLNL VSPLDCEVDA QEGDDVGRDS KRRRLV
//
