ID A0A1A6H5K3_NEOLE Unreviewed; 451 AA.
AC A0A1A6H5K3;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=Major facilitator superfamily (MFS) profile domain-containing protein {ECO:0008006|Google:ProtNLM};
DE Flags: Fragment;
GN ORFNames=A6R68_15878 {ECO:0000313|EMBL:OBS73584.1};
OS Neotoma lepida (Desert woodrat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea;
OC Cricetidae; Neotominae; Neotoma.
OX NCBI_TaxID=56216 {ECO:0000313|EMBL:OBS73584.1, ECO:0000313|Proteomes:UP000092124};
RN [1] {ECO:0000313|EMBL:OBS73584.1, ECO:0000313|Proteomes:UP000092124}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=417 {ECO:0000313|EMBL:OBS73584.1};
RC TISSUE=Liver {ECO:0000313|EMBL:OBS73584.1};
RA Campbell M., Oakeson K.F., Yandell M., Halpert J.R., Dearing D.;
RT "The Draft Genome Sequence and Annotation of the Desert Woodrat Neotoma
RT lepida.";
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OBS73584.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; LZPO01045255; OBS73584.1; -; Genomic_DNA.
DR STRING; 56216.A0A1A6H5K3; -.
DR Proteomes; UP000092124; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 1.
DR InterPro; IPR036259; MFS_trans_sf.
DR PANTHER; PTHR23121:SF11; MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING 4B5; 1.
DR PANTHER; PTHR23121; SODIUM-DEPENDENT GLUCOSE TRANSPORTER 1; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000092124};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 40..60
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 86..109
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 130..149
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 189..211
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 232..259
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 305..322
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 328..350
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 362..385
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 391..411
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 432..451
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 451
FT /evidence="ECO:0000313|EMBL:OBS73584.1"
SQ SEQUENCE 451 AA; 48792 MW; 4565525A1B8B9C75 CRC64;
MESRXSQAKA VGQRLLQAET PGKNGLQTVS SGQVGRMLRW FTTVVLNAAF LGMGVSAAVL
GPTFPDLARN VNRNISSLSE IFVGRALGYL CGSVVGGVLF DCMNHFLLLG GNVLILNLWG
DKGAPHMQTL HFSFALGAFL APLLAKLAWG TTASTYNHTE PGFDRSALNQ FSEATSDSLF
AVPDDVNLLW AYASIGTYVL VVSVFLFAPL FKQSSKQKKS TMSXQGIRRA KYHWALLCLL
FLFFFFYVGA EVTYSSYIFT FATTHVGMEE TEAAGLNSVF WGTFAACRGL AIFFATLLQP
GTMIVLCNVS SLVSSFFLVL FDKSPLCLWI ATSVYGASMA ATFPSGISWI EQYTSLSGKS
AAFILIGAAL GVMATPALSG ILQGHYPDLP IILYTCLGSA VLTTALFPAM YKLATLRLDC
KQEKIINSEG QKFLPSSSGL QGRKRKDEDK C
//
