ID A0A1A6H6Y9_NEOLE Unreviewed; 463 AA.
AC A0A1A6H6Y9;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=Tripartite motif-containing protein 65 {ECO:0008006|Google:ProtNLM};
GN ORFNames=A6R68_12049 {ECO:0000313|EMBL:OBS73372.1};
OS Neotoma lepida (Desert woodrat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea;
OC Cricetidae; Neotominae; Neotoma.
OX NCBI_TaxID=56216 {ECO:0000313|EMBL:OBS73372.1, ECO:0000313|Proteomes:UP000092124};
RN [1] {ECO:0000313|EMBL:OBS73372.1, ECO:0000313|Proteomes:UP000092124}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=417 {ECO:0000313|EMBL:OBS73372.1};
RC TISSUE=Liver {ECO:0000313|EMBL:OBS73372.1};
RA Campbell M., Oakeson K.F., Yandell M., Halpert J.R., Dearing D.;
RT "The Draft Genome Sequence and Annotation of the Desert Woodrat Neotoma
RT lepida.";
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OBS73372.1}.
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DR EMBL; LZPO01046803; OBS73372.1; -; Genomic_DNA.
DR STRING; 56216.A0A1A6H6Y9; -.
DR Proteomes; UP000092124; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0002376; P:immune system process; IEA:UniProtKB-KW.
DR CDD; cd19835; Bbox2_TRIM65_C-IV; 1.
DR CDD; cd16609; RING-HC_TRIM65_C-IV; 1.
DR CDD; cd12896; SPRY_PRY_TRIM65; 1.
DR Gene3D; 2.60.120.920; -; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR001870; B30.2/SPRY.
DR InterPro; IPR043136; B30.2/SPRY_sf.
DR InterPro; IPR003879; Butyrophylin_SPRY.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR006574; PRY.
DR InterPro; IPR003877; SPRY_dom.
DR InterPro; IPR048222; TRIM65_SPRY_PRY.
DR InterPro; IPR000315; Znf_B-box.
DR InterPro; IPR018957; Znf_C3HC4_RING-type.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR017907; Znf_RING_CS.
DR PANTHER; PTHR25465; B-BOX DOMAIN CONTAINING; 1.
DR PANTHER; PTHR25465:SF29; TRIPARTITE MOTIF-CONTAINING PROTEIN 65; 1.
DR Pfam; PF00622; SPRY; 1.
DR Pfam; PF00643; zf-B_box; 1.
DR Pfam; PF00097; zf-C3HC4; 1.
DR PRINTS; PR01407; BUTYPHLNCDUF.
DR SMART; SM00336; BBOX; 1.
DR SMART; SM00589; PRY; 1.
DR SMART; SM00184; RING; 1.
DR SMART; SM00449; SPRY; 1.
DR SUPFAM; SSF57845; B-box zinc-binding domain; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS50188; B302_SPRY; 1.
DR PROSITE; PS00518; ZF_RING_1; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Immunity {ECO:0000256|ARBA:ARBA00022859};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000092124};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT DOMAIN 12..51
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT DOMAIN 257..450
FT /note="B30.2/SPRY"
FT /evidence="ECO:0000259|PROSITE:PS50188"
SQ SEQUENCE 463 AA; 51684 MW; A0DDE93C6301D5FA CRC64;
MAARLLEEDL ACSICLGRYR DPVTLPCGHS FCGGCIQDSW RCCEKTCPEC RQPFPEGAKL
CRNVTLSTLL QALQAQPAAI PRPEPDAGHS ERCPRHGRPL EFFCRTDGLC VCSACTVHEC
RHHERALLDV ERRVRESSAC TLASVVSNRF SSLLQALEKL QALTLGNIEV AKKQALGQAL
SEIQRLTGHL EALTQYDHSV QDLLGQVDDY IFFQELQQLS EPVESLGPLT ALQWDEEQXL
NNVNEVLSPL CELLLEEKPP RVAGKAAHAG PVDYRNLTFD PDTANQYLYL SHKDQQVTHH
FQAQGSARPG SFELWQVQCT QSFQTGRHYW EVRASDHSVT LGITYPKLSR RKVGTHTDNI
GRGPSSWGLC IQEDSIQAWH NGKAQRLHGV PGRLLGIDLN LTSGCLTFYS LEPQTQRLHT
FYAVFSQPLF PVFWLLEGRT LTLCXQPEAK LPPGPTEEAS ALT
//
