ID A0A1A6H9H7_NEOLE Unreviewed; 432 AA.
AC A0A1A6H9H7;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=FAM69 N-terminal domain-containing protein {ECO:0000259|SMART:SM01299};
GN ORFNames=A6R68_14514 {ECO:0000313|EMBL:OBS74949.1};
OS Neotoma lepida (Desert woodrat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea;
OC Cricetidae; Neotominae; Neotoma.
OX NCBI_TaxID=56216 {ECO:0000313|EMBL:OBS74949.1, ECO:0000313|Proteomes:UP000092124};
RN [1] {ECO:0000313|EMBL:OBS74949.1, ECO:0000313|Proteomes:UP000092124}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=417 {ECO:0000313|EMBL:OBS74949.1};
RC TISSUE=Liver {ECO:0000313|EMBL:OBS74949.1};
RA Campbell M., Oakeson K.F., Yandell M., Halpert J.R., Dearing D.;
RT "The Draft Genome Sequence and Annotation of the Desert Woodrat Neotoma
RT lepida.";
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000256|ARBA:ARBA00004648}; Single-pass type II membrane protein
CC {ECO:0000256|ARBA:ARBA00004648}. Membrane
CC {ECO:0000256|ARBA:ARBA00004606}; Single-pass type II membrane protein
CC {ECO:0000256|ARBA:ARBA00004606}.
CC -!- SIMILARITY: Belongs to the DIPK family.
CC {ECO:0000256|ARBA:ARBA00006338}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OBS74949.1}.
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DR EMBL; LZPO01044266; OBS74949.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1A6H9H7; -.
DR STRING; 56216.A0A1A6H9H7; -.
DR Proteomes; UP000092124; Unassembled WGS sequence.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR022049; FAM69_kinase_dom.
DR InterPro; IPR029244; FAM69_N.
DR PANTHER; PTHR21093:SF3; DIVERGENT PROTEIN KINASE DOMAIN 1B; 1.
DR PANTHER; PTHR21093; UNCHARACTERIZED; 1.
DR Pfam; PF12260; PIP49_C; 1.
DR Pfam; PF14875; PIP49_N; 1.
DR SMART; SM01299; PIP49_N; 1.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000092124};
KW Signal {ECO:0000256|SAM:SignalP};
KW Signal-anchor {ECO:0000256|ARBA:ARBA00022968};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..432
FT /note="FAM69 N-terminal domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5008346207"
FT TRANSMEM 29..49
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 23..181
FT /note="FAM69 N-terminal"
FT /evidence="ECO:0000259|SMART:SM01299"
SQ SEQUENCE 432 AA; 49034 MW; 3F5A379229443878 CRC64;
MRRLRRLVHL VLLCPFSKGL QQGRLPGLRI KYVLLVWLGI FVGSWMVYVH YSSYSELCRG
HVCQVVICDQ YHKGIISGSV CQDLCELQKV EWRTCLSSAP GQQVYSGLWQ DKEVTIKCGI
EEALNSKAWP DAVPRRELVL FDKPTRGTSI KEFREMILSF LKVNLGDLPT LPALVDQILL
MADFNKDSRV SLAEAKSVWA LLQRNEFLLL LSLQEKEHAS RLLGYCGDLY LTEGIPHGSW
HGAVLLPALR PLLPSVLHRA LQQWFGPAWP WRAKIAIGLL EFVEELFHGS YGTFYMCETT
LANVGYTATY DFKMADLQQV APEATVRRFL QGRHCEQSSD CIYGRDCRAP CDRLMRQCKG
DLIQPNLAKV CELLRDYLLP GAPADLREEL GKQLRTCTTL SGLASQVEAH HSLVLSHLKT
LLWREISNTN YS
//
